Symptoms and Needs of Head and Neck Cancer Patients at Diagnosis of Incurability - Prevalences, Clinical Implications, and Feasibility of a Prospective Longitudinal Multicenter Cohort Study

2016 ◽  
Vol 39 (4) ◽  
pp. 186-191 ◽  
Author(s):  
Bernd Alt-Epping ◽  
Wiebke Seidel ◽  
Jeannette Vogt ◽  
Anja Mehnert ◽  
Michael Thomas ◽  
...  
BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Chien-Liang Lin ◽  
Shang-Yin Wu ◽  
Wen-Tsung Huang ◽  
Yin-Hsun Feng ◽  
Ching-Yi Yiu ◽  
...  

2016 ◽  
Vol 34 (8) ◽  
pp. 326-330 ◽  
Author(s):  
Fernanda Aurora Stabile Gonnelli ◽  
Luiz Felipe Palma ◽  
Adelmo José Giordani ◽  
Aline Lima Silva Deboni ◽  
Rodrigo Souza Dias ◽  
...  

2007 ◽  
Vol 77 (6) ◽  
pp. 382-388
Author(s):  
Djuric ◽  
Ronis ◽  
Fowler ◽  
Ren ◽  
Duffy

Smoking negatively affects serum carotenoid levels, and it is a negative prognostic factor for head and neck cancer. In this study, micronutrient levels were examined in 60 smoking and non-smoking head and neck cancer patients. The goal was to determine if oxidation of the carotenoid lycopene would occur to a greater extent in smokers. Subjects were drawn from a prospective cohort study and matched on seven demographic factors. Serum levels of α-carotene, zeaxanthin, and 2,6-cyclolycopene-1,5-diol A, an oxidation product of lycopene, were all lower in smokers versus non-smokers (18%, 22%, and 8%, respectively) while β-carotene, β-cryptoxanthin, and lutein were about the same in the two groups. Levels of lycopene, γ-tocopherol, and α-tocopherol were higher in smokers, and notably serum α-tocopherol was 48% higher in smokers. The majority of vitamin E intake was from supplements. The higher levels of α-tocopherol in smokers were interesting in that higher α-tocopherol levels have been associated with higher mortality in head and neck cancer. Although this was a pilot investigation, there was no evidence that 2,6-cyclolycopene-1,5-diol A formation was appreciably affected by smoking status, but α-tocopherol levels were higher in smokers.


2014 ◽  
Vol 110 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Charlotte Rotbøl Bøje ◽  
Susanne O. Dalton ◽  
Hanne Primdahl ◽  
Claus A. Kristensen ◽  
Elo Andersen ◽  
...  

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