Short-Term Results Analysis in the Allogenic Transplantation of Limbal Stem Cells Expanded on Amniotic Membrane in Patients with Bilateral Limbal Stem Cell Deficiency

2020 ◽  
Vol 36 (4) ◽  
pp. 238-246
Author(s):  
Juan Carlos Serna-Ojeda ◽  
Mariana García-Mejía ◽  
Enrique O. Graue-Hernández ◽  
Alejandro Navas ◽  
Yonathan Garfias
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Amniotic Membrane ◽  
Limbal Stem Cell Deficiency ◽  
Short Term ◽  
Limbal Stem Cells ◽  
Allogenic Transplantation ◽  
Limbal Stem Cell

scholarly journals Limbal stem cell deficiency: special focus on tracking limbal stem cells

2016 ◽  
Vol 40 ◽  
pp. 1059-1067
Author(s):  
Santhosh KACHAM ◽  
Bhaskar BIRRU ◽  
Sreenivasa Rao PARCHA ◽  
Ramaraju BAADHE
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Limbal Stem Cell Deficiency ◽  
Special Focus ◽  
Limbal Stem Cells ◽  
Limbal Stem Cell

scholarly journals Corneal epithelial changes following reconstruction by transplantation of limbal stem cells in goats with total limbal stem cell deficiency

Cell Research ◽  
2008 ◽  
Vol 18 (S1) ◽  
pp. S72-S72
Author(s):  
Shengli Mi ◽  
Zhongying Dou ◽  
Qingmei Zhao ◽  
Xueyi Yang ◽  
Lei Qu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Limbal Stem Cell Deficiency ◽  
Limbal Stem Cells ◽  
Corneal Epithelial ◽  
Limbal Stem Cell

scholarly journals Current approaches to the problem of carrier selection for limbal stem cells cultivation in the treatment of limbal stem cell deficiency

2018 ◽  
Vol 11 (2) ◽  
pp. 48-56 ◽  
Author(s):  
Alexey N. Kulikov ◽  
Sergey V. Churashov ◽  
Valeriy F. Chernysh ◽  
Miralda I. Blinova ◽  
Olga I. Alexandrova ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Ocular Surface ◽  
Contact Lenses ◽  
Ex Vivo ◽  
Limbal Stem Cell Deficiency ◽  
Epithelial Stem Cells ◽  
Limbal Stem Cells ◽  
Carrier Selection ◽  
Limbal Stem Cell

Diseases and damages of the ocular surface are one of the common causes of decreased vision and blindness. Dysfunction or death of limbal epithelial stem cells (LESC) plays an important role in the development of pathological processes in these conditions, which leads to the development of the limbal stem cell deficiency (LSCD). Currently, one of the methods to treat LSCD is a transplantation of cultured ex vivo LESC. The most common carriers for the cultivation of LESC in the world is the amniotic membrane (AM). However, the presence of certain disadvantages in using AM for the cultivation of LESC compels to search new types of carriers made from biological or synthetic materials. In this review, we have analyzed various types of carriers: collagen, fibrin, chitosan with gelatin, silk fibroin, keratin, contact lenses, polylactide-co-glycolide, polycaprolactone, and the possibility of their application as carriers for the LESC cultivation followed by transplantation on the ocular surface is considered.

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