Objective: The aim of the present study is to investigate the effect of paradoxical sleep deprivation (SD) on learning and memory impairment and anxiety-like behavior in female Wistar albino rats.
Methods: Eight-arm radial maze, open-field test, and light and dark test were used to assess the animals learning and memory and anxiety-like behavior.
Results: SD associated with weaker learning and memory and increased anxiety- and depressive-like behavior in animals.
Conclusion: Animals were exposed to SD showed learning and memory impairment and also exhibited increased anxiety- and depressive-like behavior when compared to control animals.
Sleep Deprivation in the Rat: IV. Paradoxical Sleep Deprivation