scholarly journals Complete Eradication of Xenograft Hepatoma by Oncolytic Adenovirus ZD55 Harboring TRAIL-IETD-Smac Gene with Broad Antitumor Effect

2012 ◽  
Vol 23 (9) ◽  
pp. 992-1002 ◽  
Author(s):  
Shi-bing Wang ◽  
Yuan Tan ◽  
Wen Lei ◽  
Yi-gang Wang ◽  
Xiu-mei Zhou ◽  
...  
2017 ◽  
Vol 28 (8) ◽  
pp. 690-700 ◽  
Author(s):  
Sujing Yuan ◽  
Yu Wu ◽  
Yigang Wang ◽  
Jianhua Chen ◽  
Liang Chu

Gene Therapy ◽  
2008 ◽  
Vol 15 (7) ◽  
pp. 484-494 ◽  
Author(s):  
L Chu ◽  
J Gu ◽  
L Sun ◽  
Q Qian ◽  
C Qian ◽  
...  

Open Medicine ◽  
2018 ◽  
Vol 14 (1) ◽  
pp. 1-9
Author(s):  
Jiali Hao ◽  
Wenjie Xie ◽  
Hui Li ◽  
Runsheng Li

AbstractProstate cancer (PCa) is the second most diagnosed cancer in Western male population. In this study, we insert mK5 (the mutational kringle5 of human plasminogen) into a DD3-promoted (differential display code 3) oncolytic adenovirus to construct OncoAd.mK5.DD3. E1A.dE1B, briefly, OAd.DD3.mK5. DD3 is one of the most prostate cancer specific promoters which can transcriptionally control adenoviral replication. mK5 has been proved to be able to inhibit the tumor angiogenesis and inhibit cell proliferation. Our results suggested that targeting PCa with OAd.DD3.mK5 elicited strong antitumor effect.


2009 ◽  
Vol 54 (7) ◽  
pp. 1606-1606 ◽  
Author(s):  
Juming Ma ◽  
Xiaoping He ◽  
Weiguo Wang ◽  
Yao Huang ◽  
Lin Chen ◽  
...  

2017 ◽  
Vol 03 (01) ◽  
Author(s):  
Xin Yuan Liu ◽  
Kang Jian Zhang ◽  
Jin Fa Gu ◽  
Xian Long Fangi ◽  
Ai min Ni ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document