scholarly journals Large-Scale Production of High-Quality Helper-Dependent Adenoviral Vectors Using Adherent Cells in Cell Factories

2010 ◽  
Vol 21 (1) ◽  
pp. 120-126 ◽  
Author(s):  
Masataka Suzuki ◽  
Racel Cela ◽  
Christian Clarke ◽  
Terry K. Bertin ◽  
Susana Mouriño ◽  
...  
Keyword(s):  
Large Scale ◽  
Adenoviral Vectors ◽  
Adherent Cells ◽  
Scale Production ◽  
High Quality ◽  
Cell Factories ◽  
Large Scale Production

Thermal Laser Separation – A Novel Dicing Technology Fulfilling the Demands of Volume Manufacturing of 4H-SiC Devices

2015 ◽  
Vol 821-823 ◽  
pp. 528-532 ◽  
Author(s):  
Dirk Lewke ◽  
Karl Otto Dohnke ◽  
Hans Ulrich Zühlke ◽  
Mercedes Cerezuela Barret ◽  
Martin Schellenberger ◽  
...  
Keyword(s):  
Experimental Data ◽  
Process Control ◽  
Tool Wear ◽  
Large Scale ◽  
State Of The Art ◽  
Scale Production ◽  
High Quality ◽  
Large Scale Production ◽  
Laser Separation

One challenge for volume manufacturing of 4H-SiC devices is the state-of-the-art wafer dicing technology – the mechanical blade dicing which suffers from high tool wear and low feed rates. In this paper we discuss Thermal Laser Separation (TLS) as a novel dicing technology for large scale production of SiC devices. We compare the latest TLS experimental data resulting from fully processed 4H-SiC wafers with results obtained by mechanical dicing technology. Especially typical product relevant features like process control monitoring (PCM) structures and backside metallization, quality of diced SiC-devices as well as productivity are considered. It could be shown that with feed rates up to two orders of magnitude higher than state-of-the-art, no tool wear and high quality of diced chips, TLS has a very promising potential to fulfill the demands of volume manufacturing of 4H-SiC devices.

Large-scale production of high-quality reduced graphene oxide

2013 ◽  
Vol 233 ◽  
pp. 297-304 ◽  
Author(s):  
Shichoon Lee ◽  
Sung Hun Eom ◽  
Jin Suk Chung ◽  
Seung Hyun Hur
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Large Scale ◽  
Scale Production ◽  
High Quality ◽  
Large Scale Production ◽  
Reduced Graphene

scholarly journals Extensive Screening of Green Solvents for Safe and Sustainable UiO-66 Synthesis

2020 ◽  
Author(s):  
Diletta Morelli Venturi ◽  
Filippo Campana ◽  
Fabio Marmottini ◽  
Ferdinando Costantino ◽  
Luigi Vaccaro
Keyword(s):  
Large Scale ◽  
Low Cost ◽  
Metal Organic Framework ◽  
Dimethyl Formamide ◽  
Scale Production ◽  
Green Solvents ◽  
High Quality ◽  
Color Code ◽  
Large Scale Production ◽  
Metal Organic

<p>Zirconium based Metal-Organic Framework UiO-66 is to date considered one of the benchmark compound among stable MOFs and it has attracted a huge attention for its employment in many strategic applications. Large scale production of UiO-66 for industrial purposes requires the use of safe and green solvents, fulfilling the green chemistry principles and able to replace the use of <i>N,N</i>-Dimethyl-Formamide (DMF), which, despite its toxicity, is still considered the most efficient solvent for obtaining UiO-66 of high quality. Herein we report on a survey of about 40 different solvents with different polarity, boiling point and acidity, used for the laboratory scale synthesis of high quality UiO-66 crystals. The solvents were chosen according the European REACH Regulation 1907/2006 among those having low cost, low toxicity and fully biodegradable. Concerning MOF synthesis, the relevant parameters chosen for establishing the quality of the results obtained are the degree are the crystallinity, microporosity and specific surface area, yield and solvent recyclability. Taking into account also the chemical physical properties of all the solvents, a color code was assigned in order to give a final green assessment for the UiO-66 synthesis. Defectivity of the obtained products, the use of acidic modulators and the use of alternative Zr-salts have been also taken into consideration. Preliminary results lead to conclude that GVL (γ-valerolactone) is among the most promising solvents for replacing DMF in UiO-66 MOF synthesis. </p>

scholarly journals Extensive Screening of Green Solvents for Safe and Sustainable UiO-66 Synthesis

2020 ◽  
Author(s):  
Diletta Morelli Venturi ◽  
Filippo Campana ◽  
Fabio Marmottini ◽  
Ferdinando Costantino ◽  
Luigi Vaccaro
Keyword(s):  
Large Scale ◽  
Low Cost ◽  
Metal Organic Framework ◽  
Dimethyl Formamide ◽  
Scale Production ◽  
Green Solvents ◽  
High Quality ◽  
Color Code ◽  
Large Scale Production ◽  
Metal Organic

<p>Zirconium based Metal-Organic Framework UiO-66 is to date considered one of the benchmark compound among stable MOFs and it has attracted a huge attention for its employment in many strategic applications. Large scale production of UiO-66 for industrial purposes requires the use of safe and green solvents, fulfilling the green chemistry principles and able to replace the use of <i>N,N</i>-Dimethyl-Formamide (DMF), which, despite its toxicity, is still considered the most efficient solvent for obtaining UiO-66 of high quality. Herein we report on a survey of about 40 different solvents with different polarity, boiling point and acidity, used for the laboratory scale synthesis of high quality UiO-66 crystals. The solvents were chosen according the European REACH Regulation 1907/2006 among those having low cost, low toxicity and fully biodegradable. Concerning MOF synthesis, the relevant parameters chosen for establishing the quality of the results obtained are the degree are the crystallinity, microporosity and specific surface area, yield and solvent recyclability. Taking into account also the chemical physical properties of all the solvents, a color code was assigned in order to give a final green assessment for the UiO-66 synthesis. Defectivity of the obtained products, the use of acidic modulators and the use of alternative Zr-salts have been also taken into consideration. Preliminary results lead to conclude that GVL (γ-valerolactone) is among the most promising solvents for replacing DMF in UiO-66 MOF synthesis. </p>

scholarly journals Large-scale production of lentiviral vectors using multilayer cell factories

2018 ◽  
Vol 5 (2) ◽  
pp. 90 ◽  
Author(s):  
Nathan Rout-Pitt ◽  
Alexandra McCarron ◽  
Chantelle McIntyre ◽  
David Parsons ◽  
Martin Donnelley
Keyword(s):  
Large Scale ◽  
Lentiviral Vectors ◽  
Scale Production ◽  
Cell Factories ◽  
Large Scale Production

Preparation of high-quality graphene using triggered microwave reduction under an air atmosphere

2018 ◽  
Vol 6 (7) ◽  
pp. 1829-1835 ◽  
Author(s):  
Wen-Shuai Jiang ◽  
Chao Yang ◽  
Guo-Xing Chen ◽  
Xiao-Qing Yan ◽  
Shao-Nan Chen ◽  
...  
Keyword(s):  
Large Scale ◽  
Reduction Method ◽  
Low Cost ◽  
Scale Production ◽  
High Quality ◽  
Air Atmosphere ◽  
Large Scale Production

High-quality intrinsic graphene can be prepared by a simple triggered microwave reduction method under air conditions, which provides a simple and low-cost route for large-scale production of high-quality graphene.

Large-scale production of high-quality graphene using glucose and ferric chloride

2014 ◽  
Vol 5 (12) ◽  
pp. 4656-4660 ◽  
Author(s):  
Binbin Zhang ◽  
Jinliang Song ◽  
Guanying Yang ◽  
Buxing Han
Keyword(s):  
Ferric Chloride ◽  
Large Scale ◽  
Scale Production ◽  
High Quality ◽  
Large Scale Production ◽  
Novel Method

A novel method to prepare high-quality graphene is developed using simple calcination of a mixture of glucose and FeCl3.

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