Incidence and predictors of acute mountain sickness among trekkers on Mount Kilimanjaro

2010 ◽  
Vol 11 (3) ◽  
pp. 217-222 ◽  
Author(s):  
Stewart J. Jackson ◽  
James Varley ◽  
Claudia Sellers ◽  
Katherine Josephs ◽  
Lucy Codrington ◽  
...  
Keyword(s):  
Acute Mountain Sickness ◽  
Mount Kilimanjaro ◽  
Mountain Sickness

Mountain neurology

2019 ◽  
Vol 19 (5) ◽  
pp. 404-411 ◽  
Author(s):  
Marieke Cornelia Johanna Dekker ◽  
Mark H Wilson ◽  
William Patrick Howlett
Keyword(s):  
High Altitude ◽  
Acute Mountain Sickness ◽  
Free Standing ◽  
Mount Kilimanjaro ◽  
Northern Tanzania ◽  
Neurological Conditions ◽  
Mountain Sickness ◽  
Low Altitude ◽  
Mountain Climbers ◽  
Altitude Illnesses

Mountain climbers may develop specific illnesses that largely depend on the altitude reached and the rate of ascent. The popularity of travel to high altitude destinations, extreme tourist activities and mountain climbing means that neurologists in low-altitude countries are increasingly likely to encounter neurological problems and disorders in people exposed to high altitude. Additionally, they may have to advise patients with pre-existing neurological conditions on the risks of ascent to altitude. This article focuses on neurological-related high-altitude illnesses: acute mountain sickness and high-altitude cerebral oedema, as well as high-altitude retinopathy and other neurological disorders. This overview combines current understood pathogenesis with the experience of managing altitude-related illness at the foot of Mount Kilimanjaro in northern Tanzania, the tallest free-standing mountain in the world.

Cysteinyl Leukotriene Blockade Does Not Prevent Acute Mountain Sickness

2004 ◽  
Author(s):  
S. R. Muza ◽  
D. Kaminsky ◽  
C. S. Fulco ◽  
L. E. Banderet ◽  
A. Cymerman
Keyword(s):  
Acute Mountain Sickness ◽  
Cysteinyl Leukotriene ◽  
Mountain Sickness

Optic nerve sheath diameter changes at high altitude and in acute mountain sickness: meta-regression analyses

2020 ◽  
pp. bjophthalmol-2020-317717
Author(s):  
Tou-Yuan Tsai ◽  
George Gozari ◽  
Yung-Cheng Su ◽  
Yi-Kung Lee ◽  
Yu-Kang Tu
Keyword(s):  
Optic Nerve ◽  
High Altitude ◽  
Acute Mountain Sickness ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Cochrane Library ◽  
Regression Analyses ◽  
Spline Regression ◽  
Nerve Sheath ◽  
Mountain Sickness

Background/aimsTo assess changes in optic nerve sheath diameter (ONSD) at high altitude and in acute mountain sickness (AMS).MethodsCochrane Library, EMBASE, Google Scholar and PubMed were searched for articles published from their inception to 31st of July 2020. Outcome measures were mean changes of ONSD at high altitude and difference in ONSD change between subjects with and without AMS. Meta-regressions were conducted to investigate the relation of ONSD change to altitude and time spent at that altitude.ResultsEight studies with 248 participants comparing ONSD from sea level to high altitude, and five studies with 454 participants comparing subjects with or without AMS, were included. ONSD increased by 0.14 mm per 1000 m after adjustment for time (95% CI: 0.10 to 0.18; p<0.01). Restricted cubic spline regression revealed an almost linear relation between ONSD change and time within 2 days. ONSD was greater in subjects with AMS (mean difference=0.47; 95% CI: 0.14 to 0.80; p=0.01; I2=89.4%).ConclusionOur analysis shows that ONSD changes correlate with altitude and tend to increase in subjects with AMS. Small study number and high heterogeneity are the limitations of our study. Further large prospective studies are required to verify our findings.

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