Retrospective Analysis of Transurethral Resection, Second-Look Resection, and Long-Term Chemo-Metaphylaxis for Superficial Bladder Cancer: Indications and Efficacy of a Differentiated Approach

2007 ◽  
Vol 21 (12) ◽  
pp. 1533-1542 ◽  
Author(s):  
Michael Schulze ◽  
Nicoletta Stotz ◽  
Jens Rassweiler
Keyword(s):  
Bladder Cancer ◽  
Retrospective Analysis ◽  
Transurethral Resection ◽  
Superficial Bladder Cancer ◽  
Second Look

The importance of second-look transurethral resection for superficial bladder cancer

2014 ◽  
Vol 8 (5) ◽  
pp. 299-305
Author(s):  
Ehab El-Barky ◽  
Ahmed Sebaey ◽  
Magdy Eltabey ◽  
Ahmed Aboutaleb ◽  
Sundus Hussein ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Transurethral Resection ◽  
Superficial Bladder Cancer ◽  
Second Look

scholarly journals Evaluation of Second-Look Transurethral Resection in Re-Staging of Patients With Superficial Bladder Cancer

2020 ◽  
Vol 18 (1) ◽  
pp. 16-22
Author(s):  
Md Masud Zaman ◽  
Md Sajid Hasan ◽  
Golam Mowla Chowdhury ◽  
Md Shafiqur Rahman ◽  
AKM Mahbubur Rahman
Keyword(s):  
Risk Factors ◽  
Bladder Cancer ◽  
Transurethral Resection ◽  
Treatment Strategy ◽  
Superficial Bladder Cancer ◽  
Bladder Tumour ◽  
Malignant Tissue ◽  
Second Look ◽  
Muscle Invasive ◽  
Initial Resection

Objective: The Objective of this study was to evaluate the second-look transurethral resection (TUR) from the base of the previously resected bladder tumour in avoidance of staging errors, possibility of changing treatment strategy, and determination of risk factors of up-staging in patients with a diagnosis of superficial bladder cancer. Materials and Methods: In this cross sectional study, 50 cases of superficial bladder cancers (pTa and pT1) were included where muscle coat were absent in histopathologic report of first TURBT. A second-look TUR from the tumour site were done after 4 weeks following the initial resection. At the second-look TUR, resection from the base of the previously resected area was performed for restaging. Finally, histopathologic findings of the second TURBT were compared with those of the initial one by appropriate statistical analysis. Results: Out of 50 patients, 27 (54%) had residual malignant tissue in histopathological report of second-look TUR, while 23 (46%) were tumour free (no residual malignant tissue) at second-look TUR. In this study, total up-staging of tumour found in 18 (36%) patients. Out of them, 6 (12%) and 2(4%) patients were up-staged from pTa to pT1 and PT2 respectively. 10 (20%) were up-staged from PT1 to muscle-invasive (pT2). So, total percentage of staging errors (under staging) detected in second-look TUR was 36% cases. Appearance (sessile), size (>3 cm) and stage (pT1) of the tumour at the initial resection were independent risk factors for up-staging to muscle invasive disease detected at second-look TURBT. Conclusions: Second-look TURBT is a valuable procedure for detection of residual tumour and accurate staging of non-muscle invasive bladder tumour. It also changed the treatment strategy of a significant proportion of patients. It is useful for tumours at high risk of recurrence and progression such as large size, sessile, multiple and T1 high grade tumours, particularly when there is inadequate or no muscularis propria in the specimen. Bangladesh Journal of Urology, Vol. 18, No. 1, Jan 2015 p.16-22

Short Schedule Intravesical Mitomycin Preceding Transurethral Resection for Recurrent Ta-T1, G1-G2 Bladder Cancer

1995 ◽  
Vol 81 (3) ◽  
pp. 191-193
Author(s):  
Massimo Maffezzini ◽  
Alchiede Simonato ◽  
Cristina Lodolo ◽  
Marco Raber ◽  
Giorgio Carmignani
Keyword(s):  
Bladder Cancer ◽  
Transurethral Resection ◽  
Small Volume ◽  
Superficial Bladder Cancer ◽  
Residual Disease ◽  
Intravesical Chemotherapy ◽  
Number Of Patients ◽  
Intravesical Instillations ◽  
Short Schedule

Aims and Background Intravesical instillations commonly follow resection, when all visible lesions have been removed, making impossible any direct assessment of efficacy. The study was conceived to evaluate the ablative effect on the tumor and the efficacy in reducing the risk of recurrence of short schedule intravesical chemotherapy administered before endoscopic resection. Study design Four weekly intravesical instillations of mitomycin C followed by transurethral resection (TUR) were administered to 31 patients with recurrent small volume superficial bladder cancer. Results At TUR no evidence of disease was found in 22 patients (70.9%) and residual disease in the remaining 9 (29.1%). At a median follow-up of 15 months (range, 3-33) 16 of 31 patients (51.6%) had recurrence of disease. The treatment was well tolerated. Conclusions Short-schedule intravesical chemotherapy can completely ablate small volume recurrent superficial bladder cancer in a relevant number of patients but is probably not sufficient to obtain long-term prophylaxis.

Effect of Routine Repeat Transurethral Resection for Superficial Bladder Cancer: A Long-term Observational Study

2003 ◽  
Vol 170 (2) ◽  
pp. 433-437 ◽  
Author(s):  
MARC-OLIVER GRIMM ◽  
CHRISTINE STEINHOFF ◽  
XENIA SIMON ◽  
PHILIPP SPIEGELHALDER ◽  
ROLF ACKERMANN ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Observational Study ◽  
Transurethral Resection ◽  
Superficial Bladder Cancer
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