Transurethral resection of superficial bladder cancer using 5-aminolevulinic acid: are there any long-term benefits?

2006 ◽  
Vol 3 (5) ◽  
pp. 254-255 ◽  
Author(s):  
Ralph W deVere White
Keyword(s):  
Bladder Cancer ◽  
Transurethral Resection ◽  
Aminolevulinic Acid ◽  
Superficial Bladder Cancer

Short Schedule Intravesical Mitomycin Preceding Transurethral Resection for Recurrent Ta-T1, G1-G2 Bladder Cancer

1995 ◽  
Vol 81 (3) ◽  
pp. 191-193
Author(s):  
Massimo Maffezzini ◽  
Alchiede Simonato ◽  
Cristina Lodolo ◽  
Marco Raber ◽  
Giorgio Carmignani
Keyword(s):  
Bladder Cancer ◽  
Transurethral Resection ◽  
Small Volume ◽  
Superficial Bladder Cancer ◽  
Residual Disease ◽  
Intravesical Chemotherapy ◽  
Number Of Patients ◽  
Intravesical Instillations ◽  
Short Schedule

Aims and Background Intravesical instillations commonly follow resection, when all visible lesions have been removed, making impossible any direct assessment of efficacy. The study was conceived to evaluate the ablative effect on the tumor and the efficacy in reducing the risk of recurrence of short schedule intravesical chemotherapy administered before endoscopic resection. Study design Four weekly intravesical instillations of mitomycin C followed by transurethral resection (TUR) were administered to 31 patients with recurrent small volume superficial bladder cancer. Results At TUR no evidence of disease was found in 22 patients (70.9%) and residual disease in the remaining 9 (29.1%). At a median follow-up of 15 months (range, 3-33) 16 of 31 patients (51.6%) had recurrence of disease. The treatment was well tolerated. Conclusions Short-schedule intravesical chemotherapy can completely ablate small volume recurrent superficial bladder cancer in a relevant number of patients but is probably not sufficient to obtain long-term prophylaxis.

Effect of Routine Repeat Transurethral Resection for Superficial Bladder Cancer: A Long-term Observational Study

2003 ◽  
Vol 170 (2) ◽  
pp. 433-437 ◽  
Author(s):  
MARC-OLIVER GRIMM ◽  
CHRISTINE STEINHOFF ◽  
XENIA SIMON ◽  
PHILIPP SPIEGELHALDER ◽  
ROLF ACKERMANN ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Observational Study ◽  
Transurethral Resection ◽  
Superficial Bladder Cancer
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