scholarly journals Removal of Synthetic Estrogen from Water by Adsorption on Modified Bentonites

2020 ◽  
Author(s):  
Halima Gallouze ◽  
Djamal-Eddine Akretche ◽  
Carla Daniel ◽  
Isabel Coelhoso ◽  
João G. Crespo
Keyword(s):  
Synthetic Estrogen

2,4,2′,4′-Tetrahydroxyazobenzene, Synthetic Estrogen of a New Type

1953 ◽  
Vol 26 (3) ◽  
pp. 162-163 ◽  
Author(s):  
Yoshiyuki Urushibara ◽  
Takeyoshi Takahashi
Keyword(s):  
Synthetic Estrogen ◽  
New Type

Effect of synthetic estrogen on platelet aggregation and vascular release of PGI2-like material in the rabbit

1980 ◽  
Vol 20 (6) ◽  
pp. 1039-1051 ◽  
Author(s):  
M.B. Elam ◽  
G.E. Limscomb ◽  
C.M. Chesney ◽  
D.A. Terragno ◽  
N.A. Terragno
Keyword(s):  
Platelet Aggregation ◽  
Synthetic Estrogen

Microbial transformation of synthetic estrogen 17α-ethinylestradiol

2009 ◽  
Vol 157 (12) ◽  
pp. 3325-3335 ◽  
Author(s):  
Tomáš Cajthaml ◽  
Zdena Křesinová ◽  
Kateřina Svobodová ◽  
Karel Sigler ◽  
Tomáš Řezanka
Keyword(s):  
Microbial Transformation ◽  
Synthetic Estrogen

Assay of the synthetic estrogen fosfestrol in pharmaceutical formulations using capillary electrophoresis

2005 ◽  
Vol 39 (3-4) ◽  
pp. 559-563 ◽  
Author(s):  
Demetrius G. Themelis ◽  
Anastasios V. Trellopoulos ◽  
Paraskevas D. Tzanavaras ◽  
Bo Karlberg
Keyword(s):  
Capillary Electrophoresis ◽  
Pharmaceutical Formulations ◽  
Synthetic Estrogen

scholarly journals Effect of alimentary synthetic estrogen on cell compensatory mechanisms in rats of different ages

Biologija ◽  
2017 ◽  
Vol 63 (2) ◽  
Author(s):  
Oleh Yermishev ◽  
Tatyana Lykholat ◽  
Olena Lykholat
Keyword(s):  
Lipid Peroxidation ◽  
Female Rats ◽  
Compensatory Mechanisms ◽  
Neurotransmitter System ◽  
Enzyme Systems ◽  
Synthetic Estrogen ◽  
System Components ◽  
Different Ages ◽  
Peroxidation Processes ◽  
Cholinergic Neurotransmitter

Results of a study of lipid peroxidation, antioxidant system components, and cholinergic neurotransmitter system in the organs of experimental rats of different ages exposed to alimentary synthetic estrogen are presented. Given the state of peroxidation processes and AChE activities in female rats exposed to xenoestrogen, it is possible to assume the possibility of the restructuring of the functioning of mediator and enzyme systems and additional strengthening of pathological symptoms. In the future, such phenomena may trigger the reduction of potential of compensatory mechanisms in compromising the health of the consumers. In puberty, females were more sensitive to nutritional synthetic estrogen than mature animals, thus proving that age is another factor in xenoestrogen exposure. Because of the changes in the rates of reactions to detoxification but not to the metabolism of estrogen received into the organism, particularly with food, with age the animals were less susceptible to the effects of these substances.

scholarly journals Dietary Intake of 17α-Ethinylestradiol Promotes HCC Progression in Humanized Male Mice Expressing Sex Hormone-Binding Globulin

2021 ◽  
Vol 22 (22) ◽  
pp. 12557
Author(s):  
Sang R. Lee ◽  
Su Hee Jeong ◽  
Jun H. Heo ◽  
Seong Lae Jo ◽  
Je-Won Ko ◽  
...  
Keyword(s):  
High Plasma ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Action ◽  
Male Mice ◽  
Hormone Binding ◽  
Wild Type ◽  
Synthetic Estrogen ◽  
Androgen Binding ◽  
Old Mice

Hepatocellular carcinoma (HCC) is a male-oriented malignancy; its progression is affected by sex hormones. 17α-ethinylestradiol (EE2) is a synthetic estrogen widely used as an oral contraceptive; however, it is unknown whether EE2 regulates sex hormone action in HCC. We investigated whether EE2 influences HCC risk in male androgenic environments, using mice expressing human sex hormone-binding globulin (SHBG). Two-week-old male mice were injected with diethyl-nitrosamine (DEN, 25 mg/kg) and fed an EE2 diet for 10 weeks from 30 weeks of age. Development and characteristics of liver cancer were evaluated in 40-week-old mice via molecular and histological analyses. Although EE2 did not increase HCC progression in wild-type mice, SHBG mice exhibited remarkably higher HCC risk when fed EE2. The livers of EE2-treated SHBG mice exhibited substantially increased pro-inflammatory necrosis with high plasma levels of ALT and HMGB1, and intrahepatic injury and fibers. Additionally, increased androgen response and androgen-mediated proliferation in the livers of EE2-treated SHBG mice and EE2-exposed hepatocytes under SHBG conditions were observed. As a competitor of SHBG-androgen binding, EE2 could bind with SHBG and increase the bioavailability of androgen. Our results revealed that EE2 is a novel risk factor in androgen-dominant men, predisposing them to HCC risk.

scholarly journals Effect of synthetic estrogen on protein anabolic action of ruminants

1971 ◽  
Vol 42 (6) ◽  
pp. 263-267
Author(s):  
Toyokazu FUKUSHIMA ◽  
Soichi TSUJI ◽  
Hideo SHIBANO
Keyword(s):  
Synthetic Estrogen ◽  
Anabolic Action

ADH-induced water permeability and particle aggregates: alteration by a synthetic estrogen

1991 ◽  
Vol 261 (1) ◽  
pp. F144-F152 ◽  
Author(s):  
G. Calamita ◽  
Y. Le Guevel ◽  
J. Bourguet
Keyword(s):  
Urinary Bladder ◽  
Water Flow ◽  
Water Permeability ◽  
Glucose Transporter ◽  
Apical Membrane ◽  
Selective Inhibition ◽  
Synthetic Estrogen ◽  
Permeability Changes ◽  
Particle Aggregates ◽  
Amphibian Urinary Bladder

In the amphibian urinary bladder, the increase in water permeability induced by antidiuretic hormone (ADH) is accompanied by the appearance of apical intramembrane particle (IMP) aggregates that are believed to contain specific channels for water. In a previous work, we have shown that 3,3'-diallyldiethylstilbestrol (DADES), a synthetic estrogen which is a blocker of the glucose transporter, also inhibits the hydrosmotic response to ADH in the bladder. Our aim in the present study was to analyze the alterations of the membrane fine structure further and to correlate them with the water permeability changes. The results point to a selective inhibition of the ADH-induced net water flow, probably due to an interference with one of the last steps of the response to the hormone. This inhibition is associated with an increase in the density of the apical IMP aggregates, which are thus probably not operational. The resting net water flow is not inhibited and, surprisingly, typical IMP aggregates are frequently observed in the apical membrane after DADES treatment. The compound also induces the appearance of unusual loose IMP clusters that can only be seen on the apical membrane of the granular cells and that share several ultrastructural similarities with the ADH-induced aggregates. These results suggest that 1) apical DADES treatment stimulates the insertion of IMP aggregates in the apical membrane of the urinary bladder and 2) DADES inhibits the ADH-induced water flow by interfering with the aggregates and thus probably by blocking the specific water channels.

scholarly journals Structural diversity of synthetic estrogen solvates

2007 ◽  
Vol 63 (a1) ◽  
pp. s208-s209
Author(s):  
J. Smits ◽  
C. Guguta ◽  
I. Eeuwijk ◽  
R. de Gelder
Keyword(s):  
Structural Diversity ◽  
Synthetic Estrogen
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