scholarly journals Effect of synthetic estrogen on protein anabolic action of ruminants

1971 ◽  
Vol 42 (6) ◽  
pp. 263-267
Author(s):  
Toyokazu FUKUSHIMA ◽  
Soichi TSUJI ◽  
Hideo SHIBANO
Keyword(s):  
Synthetic Estrogen ◽  
Anabolic Action

scholarly journals Effect of synthetic estrogen on protein anabolic action of ruminants

1972 ◽  
Vol 43 (6) ◽  
pp. 303-308
Author(s):  
Soichi TSUJI ◽  
Motoo IGUCHI ◽  
Tamio SASAO
Keyword(s):  
Synthetic Estrogen ◽  
Anabolic Action

2,4,2′,4′-Tetrahydroxyazobenzene, Synthetic Estrogen of a New Type

1953 ◽  
Vol 26 (3) ◽  
pp. 162-163 ◽  
Author(s):  
Yoshiyuki Urushibara ◽  
Takeyoshi Takahashi
Keyword(s):  
Synthetic Estrogen ◽  
New Type

Effect of synthetic estrogen on platelet aggregation and vascular release of PGI2-like material in the rabbit

1980 ◽  
Vol 20 (6) ◽  
pp. 1039-1051 ◽  
Author(s):  
M.B. Elam ◽  
G.E. Limscomb ◽  
C.M. Chesney ◽  
D.A. Terragno ◽  
N.A. Terragno
Keyword(s):  
Platelet Aggregation ◽  
Synthetic Estrogen

Microbial transformation of synthetic estrogen 17α-ethinylestradiol

2009 ◽  
Vol 157 (12) ◽  
pp. 3325-3335 ◽  
Author(s):  
Tomáš Cajthaml ◽  
Zdena Křesinová ◽  
Kateřina Svobodová ◽  
Karel Sigler ◽  
Tomáš Řezanka
Keyword(s):  
Microbial Transformation ◽  
Synthetic Estrogen

scholarly journals Parathyroid hormone induces bone formation in phosphorylation-deficient PTHR1 knockin mice

2012 ◽  
Vol 302 (10) ◽  
pp. E1183-E1188 ◽  
Author(s):  
Nabanita S. Datta ◽  
Tareq A. Samra ◽  
Abdul B. Abou-Samra
Keyword(s):  
Parathyroid Hormone ◽  
Bone Formation ◽  
Physiological Role ◽  
Receptor Internalization ◽  
Mineral Density ◽  
Trabecular Thickness ◽  
Receptor Complexes ◽  
Diaphyseal Bone ◽  
Anabolic Action

Activation of G protein-coupled receptors by agonists leads to receptor phosphorylation, internalization of ligand receptor complexes, and desensitization of hormonal response. The role of parathyroid hormone (PTH) receptor 1, PTHR1, is well characterized and known to regulate cellular responsiveness in vitro. However, the role of PTHR1 phosphorylation in bone formation is yet to be investigated. We have previously demonstrated that impaired internalization and sustained cAMP stimulation of phosphorylation-deficient (PD) PTHR1 leads to exaggerated cAMP response to subcutaneous PTH infusion in a PD knockin mouse model. To understand the physiological role of receptor internalization on PTH bone anabolic action, we examined bone parameters of wild-type (WT) and PD knockin female and male mice following PTH treatment. We found a decrease in total and diaphyseal bone mineral density in female but not in male PD mice compared with WT controls at 3–6 mo of age. This effect was attenuated at older age groups. PTH administration displayed increased bone volume and trabecular thickness in the vertebrae and distal femora of both WT and PD animals. These results suggest that PTHR1 phosphorylation does not play a major role in the anabolic action of PTH.

scholarly journals Improving bone health by optimizing the anabolic action of Wnt inhibitor multi‐targeting

JBMR Plus ◽  
2021 ◽  
Author(s):  
Roy B. Choi ◽  
Whitney A. Bullock ◽  
April M. Hoggatt ◽  
Gabriela G. Loots ◽  
Damian C. Genetos ◽  
...  
Keyword(s):  
Bone Health ◽  
Anabolic Action ◽  
Wnt Inhibitor

scholarly journals Parathyroid hormone 1-34 and skeletal anabolic action

2017 ◽  
Vol 6 (1) ◽  
pp. 14-21 ◽  
Author(s):  
L. Osagie-Clouard ◽  
A. Sanghani ◽  
M. Coathup ◽  
T. Briggs ◽  
M. Bostrom ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Anabolic Action

Assay of the synthetic estrogen fosfestrol in pharmaceutical formulations using capillary electrophoresis

2005 ◽  
Vol 39 (3-4) ◽  
pp. 559-563 ◽  
Author(s):  
Demetrius G. Themelis ◽  
Anastasios V. Trellopoulos ◽  
Paraskevas D. Tzanavaras ◽  
Bo Karlberg
Keyword(s):  
Capillary Electrophoresis ◽  
Pharmaceutical Formulations ◽  
Synthetic Estrogen
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