Three Genetic Polymorphisms of Homocysteine-Metabolizing Enzymes and Risk of Coronary Heart Disease: A Meta-Analysis Based on 23 Case–Control Studies

2012 ◽  
Vol 31 (2) ◽  
pp. 238-249 ◽  
Author(s):  
Ling Chen ◽  
Liu Liu ◽  
Kui Hong ◽  
Jianxin Hu ◽  
Xiaoshu Cheng
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Polymorphisms ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies ◽  
Metabolizing Enzymes

Soy Consumption with Risk of Coronary Heart Disease and Stroke: A Meta-Analysis of Observational Studies

2016 ◽  
Vol 46 (4) ◽  
pp. 242-252 ◽  
Author(s):  
Danfei Lou ◽  
Yuehua Li ◽  
Guoliang Yan ◽  
Jianhong Bu ◽  
Haihui Wang
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cohort Studies ◽  
Observational Studies ◽  
Meta Analysis ◽  
Case Control ◽  
Inverse Association ◽  
Case Control Studies ◽  
Relative Risks ◽  
Product Consumption

Background: The association of soy product consumption with the relative risk of cardiovascular disease remains controversial. This meta-analysis aimed at investigating whether an association exists between soy consumption and the risk of stroke and coronary heart disease (CHD) in observational studies. Methods: A systematic search of the PubMed and EMBASE databases was performed for case-control and cohort studies that assessed soy consumption and the risk of stroke and CHD. Summary relative risks (SRRs) and 95% CIs were combined by using a random-effects model. Results: Of a total of 1,266 abstracts, 5 prospective cohort and 6 case-control studies met our inclusion criteria, and comprised 4,954 stroke and 7,616 CHD events. Based on the high vs. low analyses, combining cohort studies showed no association between soy intake and risk of stroke (SRR 0.92; 95% CI 0.70-1.10; Pheterogeneity = 0.236; I2 = 29.4%) or CHD (SRR 0.97; 95% CI 0.74-1.27; Pheterogeneity = 0.020; I2 = 62.7%), although a significantly inverse association between soy intake and the risk of stroke (SRR 0.54; 95% CI 0.34-0.87; Pheterogeneity = 0.001; I2 = 79.3%) and CHD (SRR 0.66; 95% CI 0.56-0.77; Pheterogeneity = 0.421; I2 = 0) was observed in case-control studies. No association between soy isoflavone intake and the risk of stroke and CHD was identified. Conclusion: There was limited evidence to indicate that soy consumption was inversely associated with the risk of stroke and CHD, although further studies, with prospective designs that use validated questionnaires and control for important confounders, are warranted.

scholarly journals Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

PLoS Medicine ◽  
2012 ◽  
Vol 9 (2) ◽  
pp. e1001177 ◽  
Author(s):  
Robert Clarke ◽  
Derrick A. Bennett ◽  
Sarah Parish ◽  
Petra Verhoef ◽  
Mariska Dötsch-Klerk ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Publication Bias ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies

scholarly journals Human AGT -p.Met268Thr and coronary heart disease risk: a case-control study and meta-analysis

2018 ◽  
Vol 20 (1) ◽  
pp. 17-24
Author(s):  
Hanieh Mohammadi ◽  
Narges Razavi ◽  
Ali Abbasi ◽  
Faezeh Babaei ◽  
Ensiyeh Seyedrezazadeh ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Case Control Study ◽  
Disease Risk ◽  
Meta Analysis ◽  
Case Control ◽  
Heart Disease Risk ◽  
Control Study

Religion, Spirituality and Risk of Coronary Heart Disease: A Matched Case–Control Study and Meta-Analysis

2018 ◽  
Vol 58 (4) ◽  
pp. 1203-1216 ◽  
Author(s):  
Rohoullah Hemmati ◽  
Zeinab Bidel ◽  
Milad Nazarzadeh ◽  
Maryam Valadi ◽  
Somayeh Berenji ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals TGFB1 genetic polymorphisms and coronary heart disease risk: a meta-analysis

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Yingchang Lu ◽  
◽  
Jolanda MA Boer ◽  
Roza M Barsova ◽  
Olga Favorova ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Genetic Polymorphisms ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Meta Analysis ◽  
Heart Disease Risk
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