Continuous Glucose Monitoring and Glycemic Patterns in Pregnant Women with Gestational Diabetes Mellitus

2020 ◽  
Vol 22 (4) ◽  
pp. 271-277
Author(s):  
Rosa Márquez-Pardo ◽  
Isabel Torres-Barea ◽  
Juan-Antonio Córdoba-Doña ◽  
Concepcion Cruzado-Begines ◽  
Lourdes García-García-Doncel ◽  
...  
Author(s):  
Martina Gáborová ◽  
Viera Doničová ◽  
Ivana Bačová ◽  
Mária Pallayová ◽  
Martin Bona ◽  
...  

Background: The aim of the study was to compare the continuous glucose monitoring (CGM)-determined glycaemic variability (GV) of pregnant women with gestational diabetes mellitus (GDM) and without GDM (CG; control group). The secondary aim was to evaluate the association between risk factors of diabetes in pregnancy and parameters of glyceamic control. Methods: Demographic, biometric and biochemical parameters were obtained for pregnant women (20–38 years old) who after an oral glucose tolerance test were examined by 7-day continuous glucose monitoring using a iPro®2 Professional CGM. Results: The differences in GV between women with GDM and CG compared by total area under glucose curve (total AUC, (mmol·day/L) was statistically significant (p = 0.006). Other parameters of glycaemic control such as mean glucose, standard deviation, coefficient of variation, J-index, % time-above target range 7.8 mmol/L (%TAR), % time-in range 3.5–7.8 mmol/L (%TIR), time-below target range 3.5 mmol/L (%TBR), glycated haemoglobin were not significantly different in the study groups. Risk factors (a family history of diabetes, pre-pregnancy BMI, higher weight gain and age) correlated with parameters of glycaemic control. Conclusions: We found a significant difference in GV of women with and without GDM by total AUC determined from CGM. TIR metrics were close to significance. Our work points at an increased GV in relation to the risk factors of GDM. Pregnant women with risk factors have higher probability of severe GV with its consequences on maternal and fetal health state.


2016 ◽  
Vol 126 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Grażyna J. Iwanowicz-Palus ◽  
Marta Zarajczyk ◽  
Aleksandra Jakubowska ◽  
Agnieszka Bień ◽  
Ewa Rzońca

Abstract Introduction. Gestational diabetes mellitus (GDM) is the most common metabolic disorder happening to pregnant women. Some. 3-5% of all pregnant women in Poland are diagnosed with the condition. Glucose tolerance disorders or gestational diabetes recur in about 30% of women during their second (or next) pregnancy. Controlling diabetes involves many new responsibilities and sacrifices that may be difficult to bear for a pregnant woman. Aim. The aim of the present study was to examine the most common problems among pregnant women with gestational diabetes Material and methods. The study was conducted between 2015 and 2016. The authors used a diagnostic survey on 120 pregnant women with diabetes who were patients in gestational pathology and conservative gynecological treatment departments and diabetic outpatient clinics in Lublin. The χ2 test of independence was used to examine correlations between socio-demographic factors and problems experienced by pregnant women with gestational diabetes. Results. Problems with keeping a blood glucose monitoring diary were reported by women from cities different than province capitals (75%). Childless women reported problems with pricking their finger multiple times a day (60%). Insulin injections were perceived as a GDM-related problem mostly by women aged 31-35 (41.2%), women in their second pregnancy (61.8%) and women with more than one child (47.1%). Frequent visits to the doctor were perceived as a problem mostly by women aged less than 26 (42.3%), women living in rural areas (57.7%), women with higher education (84.6%), women in their first pregnancy (61.5%) and women without children (73.1%). The two last groups additionally indicated psychological burden (84.2% and 78.9%, respectively). Anxiety about the occurrence of type 2 diabetes was mainly expressed by women aged 26-30 (35.3%) and those in their second pregnancy (52.9%), whilst working women expressed concern for their own lives (78.6%). Conclusions. There is a correlation between selected problems experienced by pregnant women with GDM and socio-demographic variables such as: age, place of residence, education, professional activity and number of pregnancies and children. The results obtained suggest that there is a need for educating women about the most frequent problems that accompany pregnancy with GDM.


2012 ◽  
Vol 14 (7) ◽  
pp. 576-582 ◽  
Author(s):  
Antonietta Colatrella ◽  
Marialuisa Framarino ◽  
Vincenzo Toscano ◽  
Marzia Bongiovanni ◽  
Camilla Festa ◽  
...  

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