scholarly journals The Effect of Glycemic Variability on Counterregulatory Hormone Responses to Hypoglycemia in Young Children and Adolescents with Type 1 Diabetes

2011 ◽  
Vol 13 (11) ◽  
pp. 1085-1089 ◽  
Author(s):  
Nora Alghothani ◽  
Kathleen M. Dungan
Author(s):  
Warinpapha Homhuan ◽  
Preamrudee Poomthavorn ◽  
Witchuri Paksi ◽  
Patcharin Khlairit ◽  
Arkom Nongnuch ◽  
...  

2021 ◽  
Vol 8 (3) ◽  
pp. 303-308
Author(s):  
Aysun Ata ◽  
Gürel Arı ◽  
Hafize Işıklar ◽  
Günay Demir ◽  
Yasemin Atik Altınok ◽  
...  

2015 ◽  
Vol 17 (9) ◽  
pp. 605-610 ◽  
Author(s):  
Beata Mianowska ◽  
Wojciech Fendler ◽  
Bartłomiej Tomasik ◽  
Wojciech Młynarski ◽  
Agnieszka Szadkowska

Author(s):  
Alexandra D Monzon ◽  
Arwen M Marker ◽  
Amy E Noser ◽  
Mark A Clements ◽  
Susana R Patton

Abstract Background Young children with Type 1 diabetes (T1D) are at risk for extreme blood glucose variability, a risk factor for suboptimal glycated hemoglobin A1c (HbA1c) and long-term health complications. We know that a reciprocal relationship exists between sleep and glycemic outcomes in older youth with T1D; however, little research has examined objective sleep in young children (<7 years) with T1D. Purpose This study examines bidirectional associations between sleep behaviors and glycemic variability in young children with T1D. Methods Thirty-nine young children with T1D (Mage 4.33 ± 1.46 years; MHbA1c 8.10 ± 1.06%) provided accelerometry data to objectively measure sleep onset latency, number of nighttime awakenings, and total sleep time. We also assessed HbA1c, average blood glucose, and glycemic variability (i.e., standard deviation of blood glucose from device downloads). We evaluated bidirectional relationships using multilevel modeling in SAS, with weekday/weekend as a Level 2 moderator. Results Children averaged 8.5 ± 1.44 hr of sleep per night, but only 12.8% met current sleep recommendations. Children experienced more nighttime awakenings, higher blood glucose, and more glycemic variability on weekends. Sleep onset latency and nighttime awakenings predicted greater glycemic variability on weekends, and weekend glycemic variability predicted increased nighttime awakenings. Conclusions Most young children with T1D did not meet sleep recommendations. Young children experienced more nighttime awakenings, higher blood glucose, and increased glycemic variability on weekends only, when routines may be less predictable. Findings suggest that one way families of young children with T1D may be able to decrease glycemic variability is to keep consistent routines on weekdays and weekends.


2014 ◽  
Vol 13 (2) ◽  
pp. 49-53
Author(s):  
Yu. G. Samoilova ◽  
M. V. Novosyolova ◽  
O. A. Oleynik

Type 1 diabetes mellitus (T1DM) is a serious medical and social problem in the whole world. Despite the presence of a large amount of accumulated knowledge to control the disease, there are methodological limitations and uncertainties of the register. In order to obtain complete information on the prevalence and incidence of T1DM among children and adolescents in order to monitor the disease, providing diagnostic and rehabilitation measures, there was a need for analysis of epidemiological climate T1DM in children and adolescents of the Tomsk region. The evaluation found that T1DM on the rise, especially among young children, which raises the need for а personalized approach in addressing this issue.


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