Prenatal Exposure to Endocrine Disruptors and Reprogramming of Adipogenesis: An Early-Life Risk Factor for Childhood Obesity

2018 ◽  
Vol 14 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Ayman El-Sayed Shafei ◽  
Enas Samir Nabih ◽  
Kirolos Atalla Shehata ◽  
Emad Sherif Mohamed Abd Elfatah ◽  
Abou bakr Ahmed Sanad ◽  
...  
2021 ◽  
Author(s):  
Torill Alise Rotevatn ◽  
Rikke Nørmark Mortensen ◽  
Line Rosenkilde Ullits ◽  
Christian Torp‐Pedersen ◽  
Charlotte Overgaard ◽  
...  

2019 ◽  
Vol 32 (5) ◽  
pp. 439-445 ◽  
Author(s):  
Mohammad Aghaali ◽  
Seyed Saeed Hashemi-Nazari

Abstract Background Recent studies have shown that antibiotic exposure during infancy is associated with increased body mass in healthy children. This study was performed to investigate the association between early-life antibiotic exposure and risk of childhood obesity. Methods A systematic review and meta-analysis was performed to comprehensively and quantitatively determine the association between early antibiotic exposure and risk of childhood obesity. Various databases such as PubMed, Embase, Scopus, Web of Science, ProQuest, Cochrane and Google Scholar were searched. A random-effects meta-analysis was performed to pool the statistical estimates. Additionally, a subgroup analysis was performed based on the time of follow-up. Results Nineteen studies involving at least 671,681 participants were finally included. Antibiotic exposure in early life was significantly associated with risk of childhood weight gain and obesity (odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.04–1.06). Conclusions Antibiotic exposure in early life significantly increases the risk of childhood weight gain and obesity.


PEDIATRICS ◽  
2010 ◽  
Vol 125 (4) ◽  
pp. 686-695 ◽  
Author(s):  
E. M. Taveras ◽  
M. W. Gillman ◽  
K. Kleinman ◽  
J. W. Rich-Edwards ◽  
S. L. Rifas-Shiman

2014 ◽  
Vol 38 ◽  
pp. 160-171 ◽  
Author(s):  
Jolien S. van Campen ◽  
Floor E. Jansen ◽  
Pierre N.E. de Graan ◽  
Kees P.J. Braun ◽  
Marian Joels

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