Early‐life childhood obesity risk prediction: A Danish register‐based cohort study exploring the predictive value of infancy weight gain

2021 ◽  
Author(s):  
Torill Alise Rotevatn ◽  
Rikke Nørmark Mortensen ◽  
Line Rosenkilde Ullits ◽  
Christian Torp‐Pedersen ◽  
Charlotte Overgaard ◽  
...  
Keyword(s):  
Cohort Study ◽  
Weight Gain ◽  
Childhood Obesity ◽  
Risk Prediction ◽  
Predictive Value ◽  
Early Life ◽  
Obesity Risk

scholarly journals Reducing Hispanic Children’s Obesity Risk Factors in the First 1000 Days of Life: A Qualitative Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Jennifer A. Woo Baidal ◽  
Shaniece Criss ◽  
Roberta E. Goldman ◽  
Meghan Perkins ◽  
Courtney Cunningham ◽  
...  
Keyword(s):  
Risk Factors ◽  
Weight Gain ◽  
Childhood Obesity ◽  
Early Life ◽  
Infant Development ◽  
Extended Family ◽  
Later Life ◽  
Obesity Risk ◽  
Important Health ◽  
Obesity Risk Factors

Objectives. Modifiable behaviors during the first 1000 days (conception age 24 months) mediate Hispanic children’s obesity disparities. We aimed to examine underlying reasons for early life obesity risk factors and identify potential early life intervention strategies.Methods. We conducted 7 focus groups with 49 Hispanic women who were pregnant or had children < age 24 months. Domains included influences on childhood obesity risk factors and future intervention ideas. We analyzed data with immersion-crystallization methods until no new themes emerged.Results. Themes included coping with pregnancy may trump healthy eating and physical activity; early life weight gain is unrelated to later life obesity; fear of infant hunger drives bottle and early solids introduction; beliefs about infant taste promote early solids and sugary beverage introduction; and belief that screen time promotes infant development. Mothers identified physicians, nutritionists, and relatives as important health information sources and expressed interest in mobile technology and group or home visits for interventions.Conclusion. Opportunities exist in the first 1000 days to improve Hispanic mothers’ understanding of the role of early life weight gain in childhood obesity and other obesity risk factors. Interventions that link health care and public health systems and include extended family may prevent obesity among Hispanic children.

Association between early antibiotic exposure and risk of childhood weight gain and obesity: a systematic review and meta-analysis

2019 ◽  
Vol 32 (5) ◽  
pp. 439-445 ◽  
Author(s):  
Mohammad Aghaali ◽  
Seyed Saeed Hashemi-Nazari
Keyword(s):  
Systematic Review ◽  
Weight Gain ◽  
Childhood Obesity ◽  
Early Life ◽  
Meta Analysis ◽  
Healthy Children ◽  
Antibiotic Exposure ◽  
Statistical Estimates ◽  
Childhood Weight

Abstract Background Recent studies have shown that antibiotic exposure during infancy is associated with increased body mass in healthy children. This study was performed to investigate the association between early-life antibiotic exposure and risk of childhood obesity. Methods A systematic review and meta-analysis was performed to comprehensively and quantitatively determine the association between early antibiotic exposure and risk of childhood obesity. Various databases such as PubMed, Embase, Scopus, Web of Science, ProQuest, Cochrane and Google Scholar were searched. A random-effects meta-analysis was performed to pool the statistical estimates. Additionally, a subgroup analysis was performed based on the time of follow-up. Results Nineteen studies involving at least 671,681 participants were finally included. Antibiotic exposure in early life was significantly associated with risk of childhood weight gain and obesity (odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.04–1.06). Conclusions Antibiotic exposure in early life significantly increases the risk of childhood weight gain and obesity.

scholarly journals Protocol for iGrow (Infant Growth and Development Study): biopsychosocial predictors of childhood obesity risk at 2 years

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Esther M. Leerkes ◽  
Cheryl Buehler ◽  
Susan D. Calkins ◽  
Lenka H. Shriver ◽  
Laurie Wideman
Keyword(s):  
Weight Gain ◽  
Childhood Obesity ◽  
Growth And Development ◽  
Maternal Sensitivity ◽  
Feeding Practices ◽  
Infant Growth ◽  
Obesity Risk ◽  
Development Study ◽  
Early Weight Gain ◽  
Infant Weight Gain

Abstract Background Childhood obesity remains a significant public health problem. To date, most research on the causes and correlates of obesity has focused on a small number of direct predictors of obesity rather than testing complex models that address the multifactorial nature of the origins of obesity in early development. We describe the rationale and methods of iGrow (Infant Growth and Development Study) which will test multiple pathways by which (a) prenatal maternal psychobiological risk predicts infant weight gain over the first 6 months of life, and (b) this early weight gain confers risk for obesity at age 2. Infant hormonal and psychobiological risk are proposed mediators from prenatal risk to early weight gain, though these are moderated by early maternal sensitivity and obesogenic feeding practices. In addition, higher maternal sensitivity and lower obesogenic feeding practices are proposed predictors of adaptive child self-regulation in the second year of life, and all three are proposed to buffer/reduce the association between high early infant weight gain and obesity risk at age 2. Methods iGrow is a prospective, longitudinal community-based study of 300 diverse mothers and infants to be followed across 5 data waves from pregnancy until children are age 2. Key measures include (a) maternal reports of demographics, stress, well-being, feeding practices and child characteristics and health; (b) direct observation of maternal and infant behavior during feeding, play, and distress-eliciting tasks during which infant heart rate is recorded to derive measures of vagal withdrawal; (c) anthropometric measures of mothers and infants; and (d) assays of maternal prenatal blood and infant saliva and urine. A host of demographic and other potential confounds will be considered as potential covariates in structural equation models that include tests of mediation and moderation. Efforts to mitigate the deleterious effects of COVID-19 on study success are detailed. Discussion This study has the potential to inform (1) basic science about early life processes casually related to childhood obesity and (2) development of targeted intervention and prevention approaches that consider mother, infant, and family risks and resources.

scholarly journals Correction: Associations of Infant Feeding and Timing of Weight Gain and Linear Growth during Early Life with Childhood Blood Pressure: Findings from a Prospective Population Based Cohort Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0168920 ◽  
Author(s):  
Marieke de Beer ◽  
Tanja G. M. Vrijkotte ◽  
Caroline H. D. Fall ◽  
Manon van Eijsden ◽  
Clive Osmond ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cohort Study ◽  
Weight Gain ◽  
Infant Feeding ◽  
Early Life ◽  
Linear Growth ◽  
Population Based

scholarly journals A Practical Screening Tool to Predict Early Childhood Obesity Risk: Examining a Birth Cohort

2020 ◽  
pp. 000992282097100
Author(s):  
James Gannon ◽  
Allison J. Pollock ◽  
David B. Allen ◽  
Pamela J. Kling
Keyword(s):  
Risk Factors ◽  
Childhood Obesity ◽  
Iron Deficiency ◽  
Birth Cohort ◽  
Early Life ◽  
Maternal Obesity ◽  
Maternal Diabetes ◽  
Large For Gestational Age ◽  
Obesity Risk ◽  
Total Risk

Children obese at the age of 5 years are at greater risk of lifelong obesity. Because certain risks of obesity can be identified in early infancy, a tool for obesity risk prediction in early life would be clinically useful. We investigated predictors of obesity risk in a novel, prospectively collected healthy birth cohort recruited for demographic risks to develop iron deficiency at 1 year, a cohort leveraged because risk factors for iron deficiency and obesity overlap. Obesity at the age of 5 years was defined as age- and sex-specific body mass index Z-score ( zBMI) >2SD. For each child, obesity risk factors were summed. Of 10 total risk factors, the following 4 key risks were identified: maternal obesity, maternal diabetes, large for gestational age, or breastfeeding <6 months. Childhood obesity was predicted by either ≥3 total number of risks ( P < .033), any key risk ( P < .002), or summing key risks ( P < .0001). In clinical practice, summing early life risk factors may be a useful strategy for preemptive counseling.

scholarly journals Early life risk factors for childhood obesity—Does physical activity modify the associations? The MoBa cohort study

2019 ◽  
Vol 29 (10) ◽  
pp. 1636-1646 ◽  
Author(s):  
Guro Pauck Bernhardsen ◽  
Trine Stensrud ◽  
Wenche Nystad ◽  
Knut Eirik Dalene ◽  
Elin Kolle ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cohort Study ◽  
Childhood Obesity ◽  
Early Life

scholarly journals Rapid Infancy Weight Gain and 7- to 9-year Childhood Obesity Risk

Medicine ◽  
2016 ◽  
Vol 95 (16) ◽  
pp. e3425 ◽  
Author(s):  
Jing Zhou ◽  
Shaonong Dang ◽  
Lingxia Zeng ◽  
Wenlong Gao ◽  
Duolao Wang ◽  
...  
Keyword(s):  
Weight Gain ◽  
Childhood Obesity ◽  
Obesity Risk
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