scholarly journals Generation of Neural Cells from DM1 Induced Pluripotent Stem Cells As Cellular Model for the Study of Central Nervous System Neuropathogenesis

2013 ◽  
Vol 15 (2) ◽  
pp. 166-177 ◽  
Author(s):  
Guangbin Xia ◽  
Katherine E. Santostefano ◽  
Marianne Goodwin ◽  
Jilin Liu ◽  
S.H. Subramony ◽  
...  
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Neural Cells ◽  
Cellular Model ◽  
Induced Pluripotent

scholarly journals Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus

2019 ◽  
Vol 23 (11) ◽  
pp. 7382-7394 ◽  
Author(s):  
Maria Teresa De Angelis ◽  
Gianluca Santamaria ◽  
Elvira Immacolata Parrotta ◽  
Stefania Scalise ◽  
Michela Lo Conte ◽  
...  
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Induced Pluripotent Stem Cells ◽  
Lupus Erythematosus ◽  
Pluripotent Stem Cells ◽  
Central Nervous System Lupus ◽  
Induced Pluripotent

scholarly journals Indukált pluripotens őssejtek szerepe a neurológiai betegségek modellezésében

2015 ◽  
Vol 156 (26) ◽  
pp. 1035-1039
Author(s):  
Zoltán Balogh ◽  
János Réthelyi ◽  
Mária Molnár
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Disease Modeling ◽  
Cell Physiology ◽  
Pathological State ◽  
Pathophysiological Mechanism ◽  
Induced Pluripotent

The longitudinal follow-up of the development and course of central nervous system related diseases on a molecular level was unsolved for decades. Direct examination of the pathological state on organ or tissue levels was feasible in the late stage of the disease. Modeling diseases has an important role in studying the pathophysiological mechanism underlying central nervous system disorders but animals used as model organism due to species specific nervous system differences can lead to less valid conclusions in translational research. The model of induced pluripotent stem cells may help to solve partially these types of problems. In recent years this model had a strong effect on understanding the pathogenesis of neurodegenerative and neurodevelopmental disorders. Although induced pluripotent stem cells have a low impact on clinical research studies, they have a prominent role in the field of cell physiology and molecular biology research. Orv. Hetil., 2015, 156(26), 1035–1039.

scholarly journals A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells

2013 ◽  
Vol 56 ◽  
pp. 355-364 ◽  
Author(s):  
Matthew F. Burkhardt ◽  
Fernando J. Martinez ◽  
Sarah Wright ◽  
Carla Ramos ◽  
Dmitri Volfson ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Cellular Model ◽  
Sporadic Als ◽  
Induced Pluripotent
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