scholarly journals Familial Clustering of Immune-Mediated Diseases in Children with Abrupt-Onset Obsessive Compulsive Disorder

2020 ◽  
Vol 30 (5) ◽  
pp. 345-346
Author(s):  
Avis Chan ◽  
Tiffany Phu ◽  
Bahare Farhadian ◽  
Theresa Willett ◽  
Margo Thienemann ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Abrupt Onset ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Immune Mediated ◽  
Familial Clustering

Investigating Tourette Syndrome as a Neurologic Sequela of Rheumatic Fever

CNS Spectrums ◽  
1999 ◽  
Vol 4 (2) ◽  
pp. 62-67 ◽  
Author(s):  
Roger Kurlan
Keyword(s):  
Rheumatic Fever ◽  
Obsessive Compulsive Disorder ◽  
Tourette Syndrome ◽  
Research Evidence ◽  
Streptococcal Infection ◽  
Molecular Mimicry ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Neurologic Sequela ◽  
Immune Mediated

AbstractSydenham's chorea is currently recognized as the only neurologic sequela of rheumatic fever. Recent evidence suggests that there may be a spectrum of neurobehavioral disturbances, particularly including tics and obsessive-compulsive disorder, that develops following streptococcal infection by the process of molecular mimicry, whereby antibodies directed against bacterial antigens cross-react with brain targets. This proposed postinfectious, immune-mediated condition has been termed “pediatric autoimmune neuropsychiatric disorders after streptococcal infection” (PANDAS). This article reviews research evidence in favor and also against the PANDAS concept and discusses the implications of the hypothesis.

scholarly journals Familial Clustering of Tic Disorders and Obsessive-Compulsive Disorder

2015 ◽  
Vol 72 (4) ◽  
pp. 359 ◽  
Author(s):  
Heidi A. Browne ◽  
Stefan N. Hansen ◽  
Joseph D. Buxbaum ◽  
Shannon L. Gair ◽  
Judith B. Nissen ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Tic Disorders ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Familial Clustering
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