Design and Application of the Utility System of Clinical Data and Biobank Resource of the Beijing Friendship Hospital, Capital Medical University

2018 ◽  
Vol 16 (6) ◽  
pp. 419-425
Author(s):  
Xiuhong Li ◽  
Yilin Chen ◽  
Xuan Zhang ◽  
Tao Huang ◽  
Ping Zhang ◽  
...  
Keyword(s):  
Clinical Data ◽  
Utility System ◽  
Friendship Hospital ◽  
Medical University ◽  
Beijing Friendship Hospital ◽  
Design And Application

Stem Cells in Rotator Cuff Injuries and Reconstructions: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 15 (7) ◽  
pp. 646-646
Author(s):  
Fanxiao Liu ◽  
Qingqi Meng ◽  
Heyong Yin ◽  
Zexing Yan
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Trauma Surgery ◽  
Provincial Hospital ◽  
Rotator Cuff Injuries ◽  
Wu Wei ◽  
Friendship Hospital ◽  
Medical University ◽  
Beijing China ◽  
Beijing Friendship Hospital

Current Stem Cell Research & Therapy, 2019, 14(8): 683-697 <P> Heyong Yin’s affiliation should be: Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing China; <P> Zexing Yan’s affiliation should be: Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong University, No.324, Road Jing Wu Wei Qi, Jinan 250021, Shandong, China. <P> The Original Paragraph Provided is Mentioned Below: <P> Fanxiao Liu1, Qingqi Meng2, Heyong Yin3,* and Zexing Yan3,* <P> 1Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong University, No.324, Road Jing Wu Wei Qi, Jinan 250021, Shandong, China; 3Department of Trauma Surgery, University of Regensburg, Am biopark 9, 93049 Regensburg, Germany

scholarly journals Characteristics of Endoscopic and Pathological Findings of Amebic Colitis

2020 ◽  
Author(s):  
Ying Meng ◽  
Bing Yue ◽  
Hua Yan Zhou ◽  
Ying Hai Zhao ◽  
Dong Yong Wu ◽  
...  
Keyword(s):  
Histological Examination ◽  
Amebic Colitis ◽  
Colon Crypt ◽  
Amoebic Colitis ◽  
Friendship Hospital ◽  
Laboratory Examinations ◽  
Inflammatory Bowel ◽  
Very High ◽  
Beijing Friendship Hospital ◽  
Rule Out

Abstract Background The clinical features of amoebic colitis resemble those of Inflammatory Bowel Disease (IBD), and therefore the risk of misdiagnosis is very high.Methods We retrospectively reviewed data of all amebic colitis cases admitted to Beijing Friendship Hospital from January 2015 to January 2020. Cases were diagnosed by clinical presentation, laboratory examinations, and colonoscopy with biopsy and histological examination. Results 16 patients were diagnosed with amebic colitis by colonoscopies accompanied by biopsies and microscopic examinations. At first, 12 (75%) patients were misdiagnosed with IBD. The cecum was the most common site of amebic colitis (100%), and the caecum and rectum were also involved in many lesions (68.75%). Multiple lesions of erosion and/or ulcers were recognized in all patients (100%). The features of endoscopic findings included multiple irregularly shaped ulcers and erosions with surrounding erythema, and the ulcers and erosions were covered by the white or yellow exudates. The intervening mucosae between the ulcers or erosions were normal. The features of the rectums can be divided to 2 types: in 6 patients (54.5%), the irregular ulcers or erosions covered with white or yellow exudates were observed in the rectum and the cecum, and the bloody exudates in the rectum were more severe than those in the cecum; in the other 5 patients (45.5%), rectal lesions were much less severe than those in the cecum, and small superficial erosions or reddened mucosa were observed in the rectal ampulla. All patients were diagnosed as detection of amebic trophozoites from HE-stained biopsy specimens. The number of trophozoites ranged from 1 /HPF to ＞50/HPF. Among 16 cases, mild architectural alteration of colon crypt was observed in 10 cases (62.5%), and serious architectural alteration of colon crypt was found which had a crypt branch in 1 case (16.7%). Cryptitis was observed in 12 cases (75%) and its severity was mild or moderate. No crypts abscesses were observed in all cases. Conclusions Colonoscopies with histological examinations are very important to diagnose amebic colitis. Detecting the amoebic trophozoites in the exudates by histological examination is vital. Sometimes a negative biopsy does not rule out amebiasis, repeated biopsies may be needed to make the diagnosis.

Diagnosis and Management of Giant Esophageal Fibrovascular Polyp With Hypopharyngeal Pedicle

2021 ◽  
pp. 014556132110464
Author(s):  
Wan-Xin Li ◽  
Jia-Qi Bai ◽  
Yan-Bo Dong ◽  
Liang-Fa Liu
Keyword(s):  
Upper Aerodigestive Tract ◽  
Transcervical Approach ◽  
Fibreoptic Laryngoscopy ◽  
Friendship Hospital ◽  
Oesophageal Tumour ◽  
Benign Tumours ◽  
Clinical Records ◽  
Medical University ◽  
Progressive Dysphagia

Background: Fibrovascular polyps (FVPs) with hypopharyngeal pedicles (hFVPs) are the rare intraluminal benign tumours of the upper aerodigestive tract, and their accurate diagnosis and optimal management are challenging. Purpose: The present retrospective study attempted to explore the optimal diagnosis and treatment of hFVPs. Research Design: The clinical records of 2 patients with giant, irregularly shaped hFVPs, who underwent several failed surgical procedures after inaccurate diagnosis, were reviewed. Finally, the patients were correctly diagnosed and successfully treated at Capital Medical University Beijing Friendship Hospital in different years, 2018 and 2020. Results: Case 1 was of a 43-year-old woman with 2 months of progressive dysphagia. Gastroenterologists overlooked the origin of her FVP, and decided to sever its narrowest point in the oesophagus through endoscopy. However, upon unsuccessful removal of the mass, a gastrotomy procedure was performed to extract the mass 7 days later. Symptoms recurred 3 months after the treatment, and a fibreoptic laryngoscopy confirmed hFVP in the patient at our department. A transcervical approach was used to sever the hypopharyngeal pedicle, achieve haemostasis and remove the oesophageal tumour. No recurrence was detected during the 2-year follow-up period after the treatment. Case 2 was of a 32-year-old man with dysphagia who had previously undergone transthoracic and transcervical oesophagotomy procedures within a gap of 3 months for the removal of FVP causing dysphagia. The hypopharyngeal pedicle was not diagnosed in the patient. The symptoms of dysphagia recurred 4 years after the treatment, and a fibreoptic laryngoscope confirmed hFVP at our department. The tumour was removed successfully through the transcervical approach. No recurrence was detected during the 6-months follow-up after surgery. Conclusion: In conclusion, the transcervical approach is suitable for achieving haemostasis and removing giant, irregularly shaped hFVPs.

scholarly journals Drainage smell and peritonitis are efficient indicators of anastomotic leakage after laparoscopic rectal cancer resection

2020 ◽  
Vol 48 (11) ◽  
pp. 030006052097076
Author(s):  
Enesh Shiwakoti ◽  
Jianning Song ◽  
Jun Li ◽  
Shanshan Wu ◽  
Zhongtao Zhang
Keyword(s):  
Rectal Cancer ◽  
Multivariate Analysis ◽  
Anastomotic Leakage ◽  
Roc Curves ◽  
Retrospective Case ◽  
Cancer Resection ◽  
Rectal Cancer Resection ◽  
Friendship Hospital ◽  
Beijing Friendship Hospital ◽  
Control Study

Objective Anastomotic leakage (AL) is a frequent complication after laparoscopic rectal cancer resection (LRCR). The main objective of the present study was to identify accurate indicators of AL after LRCR. Methods A retrospective case-control study was performed of 185 patients who underwent laparoscopic surgery for rectal cancer between March 2012 and February 2017 at Beijing Friendship Hospital. Potential indicators of AL were examined via univariate and multivariate analyses. The performance of multivariate analysis was evaluated using receiver operating characteristic (ROC) curves. Results The overall AL rate was 17.84%. Multivariate analysis identified drainage smell (odds ratio [OR = 35.318, 95% confidence interval [CI] = 7.114 to 175.338) and peritonitis [OR = 17.475, 95% CI = 1.540 to 198.318) as independent indicators of AL. The area under the ROC curve was 0.720 (95% CI = 0.606 to 0.835). Conclusion Drainage smell and peritonitis could be reliable and accurate indicators of AL after LRCR.

scholarly journals Case series of aortoenteric fistulas: a rare cause of gastrointestinal bleeding

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jia Luo ◽  
Wen Tang ◽  
Mengran Wang ◽  
Yao Xiao ◽  
Manhong Tan ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Management Strategies ◽  
Case Series ◽  
Final Diagnosis ◽  
Positive Outcome ◽  
Multiple Organ ◽  
Management Procedures ◽  
Friendship Hospital ◽  
Abdominal Infections ◽  
Medical University

Abstract Background Aortoenteric fistula (AEF) is a rare cause of gastrointestinal bleeding and is often misdiagnosed in clinical practice. Herein, a case series of AEFs are presented and the clinical characteristics, diagnosis, and management strategies are summarized. Methods A retrospective analysis was performed on consecutive hospitalized patients with a final diagnosis of AEF at Beijing Friendship Hospital, Capital Medical University, between January 1, 2007 and March 31, 2020. The clinical data including diagnostic and management procedures as well as outcomes were collected and summarized. Results A total of nine patients were included in this study, five with primary AEF and four with secondary AEF. Eight of the patients were male, and the median age was 63 years. The fistulas were located in both the small intestine and the colon. All patients presented with gastrointestinal bleeding and pain, followed by weight loss, anorexia, and fever. A typical abdominal triad was found in only two cases. Seven patients experienced complications with preoperative abdominal infections and sepsis, and multiple organ failure occurred in four of these patients. All patients were assessed by computed tomography and five underwent abdominal and/or iliac aorta angiography. Two of these patients showed contrast agent leakage from the abdominal aorta into the intestine. Two cases were diagnosed with AEF by endoscopy before the operation. Eight patients received surgery and six patients survived. Conclusions AEF is a rare cause of gastrointestinal bleeding that is associated with high mortality. Gastrointestinal bleeding and pain are the most common presentations. Timely diagnosis and multidisciplinary management are crucial to achieve a positive outcome.

scholarly journals Surgical Treatment of Primary Intracranial and Extracranial Communicating Leiomyosarcoma with One Case Recurred

2021 ◽  
Author(s):  
zeyi wang ◽  
kuairong pu ◽  
wencai zhang ◽  
peng chen ◽  
dongchuan shao ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Effective Treatment ◽  
Hospital Discharge ◽  
Clinical Features ◽  
Clinical Data ◽  
Diagnosis And Treatment ◽  
Treatment Experience ◽  
Medical University ◽  
Surgical Operations

Abstract backgroundTo analyze and summarize the clinical features and diagnosis and treatment experience on primary intracranial and extracranial communicating leiomyosarcoma to deepen clinicians’understanding of the rare disease.Cases presentationThe clinical data and recurrence of a patient who was diagnosed with primary intracranial and extracranial communicating leiomyosarcoma admitted to the Neurosurgery Department, The Affiliated Ganmei Hospital of Kunming Medical University in May 2015 were retrospectively analyzed. According to the patient data, two successful surgical operations were performed and the surgeries went well, with more than 2-year and 8-month follow-up so far. No obvious complications were found after hospital discharge, and follow-up was continued.ConclusionsSurgical removal is the most important and effective treatment means for primary intracranial and extracranial communicating leiomyosarcoma currently.

scholarly journals Process Mining and Conformance Checking of Long Running Processes in the Context of Melanoma Surveillance

2018 ◽  
Vol 15 (12) ◽  
pp. 2809 ◽  
Author(s):  
Christoph Rinner ◽  
Emmanuel Helm ◽  
Reinhold Dunkl ◽  
Harald Kittler ◽  
Stefanie Rinderle-Ma
Keyword(s):  
Clinical Data ◽  
Process Mining ◽  
Process Models ◽  
Time Constraints ◽  
Actual Process ◽  
Conformance Checking ◽  
Event Logs ◽  
Melanoma Surveillance ◽  
Medical University ◽  
Medical Guidelines

Background: Process mining is a relatively new discipline that helps to discover and analyze actual process executions based on log data. In this paper we apply conformance checking techniques to the process of surveillance of melanoma patients. This process consists of recurring events with time constraints between the events. Objectives: The goal of this work is to show how existing clinical data collected during melanoma surveillance can be prepared and pre-processed to be reused for process mining. Methods: We describe an approach based on time boxing to create process models from medical guidelines and the corresponding event logs from clinical data of patient visits. Results: Event logs were extracted for 1023 patients starting melanoma surveillance at the Department of Dermatology at the Medical University of Vienna between January 2010 and June 2017. Conformance checking techniques available in the ProM framework and explorative applied process mining techniques were applied. Conclusions: The presented time boxing enables the direct use of existing process mining frameworks like ProM to perform process-oriented analysis also with respect to time constraints between events.

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