scholarly journals Mitochondrial Dynamics in Cardiovascular Health and Disease

2013 ◽  
Vol 19 (4) ◽  
pp. 400-414 ◽  
Author(s):  
Sang-Bing Ong ◽  
Andrew R. Hall ◽  
Derek J. Hausenloy
2009 ◽  
Vol 84 (9) ◽  
pp. 822-830 ◽  
Author(s):  
Nisha Charkoudian ◽  
Jennifer A. Rabbitts

2008 ◽  
Vol 101 (10) ◽  
pp. S75-S86 ◽  
Author(s):  
Bradley J. Willcox ◽  
J. David Curb ◽  
Beatriz L. Rodriguez

2021 ◽  
Author(s):  
Ziyad Al-Aly ◽  
Benjamin Bowe ◽  
Yan Xie ◽  
Evan Xu

Abstract The cardiovascular complications of acute COVID-19 are well described; however, a comprehensive characterization of the post-acute cardiovascular manifestations of COVID-19 at one year has not been undertaken. Here we use the US Department of Veterans Affairs national healthcare databases to build a cohort of 151,195 people with COVID-19, 3,670,087 contemporary and 3,656,337 historical controls to estimate risks and 1-year burdens of a set of pre-specified incident cardiovascular outcomes. We show that beyond the first 30 days of infection, people with COVID-19 are at increased risk of incident cardiovascular disease spanning several categories including cerebrovascular disorders, dysrhythmias, ischemic and non-ischemic heart disease, pericarditis, myocarditis, heart failure, and thromboembolic disease. The risks and burdens were evident among those who were non-hospitalized during the acute phase of the infection and increased in a graded fashion according to care setting of the acute infection (non-hospitalized, hospitalized, and admitted to intensive care). Taken together, our results provide evidence that risk and 1-year burden of cardiovascular disease in survivors of acute COVID-19 are substantial. Care pathways of people who survived the acute episode of COVID-19 should include attention to cardiovascular health and disease.


2021 ◽  
Vol 12 ◽  
Author(s):  
Harini Narayanam ◽  
Suresh V. Chinni ◽  
Sumitha Samuggam

The role of micronutrients in health and disease has increased the curiosity and interest among researchers. The prime focus of this review is the significance of trace elements- calcium, vitamin D, selenium and zinc with cardiovascular health. WHO identified cardiovascular diseases (CVD) as the leading cause of deaths globally. Identifying the risk factors that could be modified and creating new treatment strategies remains to be the main concern for CVD prevention. The data that showed the relationship between trace elements and various ways in which they may contribute to cardiovascular health and disease from clinical trials and observational studies were collected from databases such as PubMed and Embase. Based on these collected data, it shows that either high or low circulating serum levels can be associated with the development of cardiovascular diseases. Micronutrients through diet contribute to improved cardiac health. However, due to our current lifestyle, there is a huge dependency on dietary supplements. Based on the observational studies, it is evident that supplements cause sudden increase in the circulating levels of the nutrients and result in cardiovascular damage. Thus, it is advisable to restrict the use of supplements, owing to the potent risks it may cause. In order to understand the exact mechanism between micronutrients and cardiac health, more clinical studies are required.


1979 ◽  
Vol 59 (4) ◽  
pp. 483-483
Author(s):  
Dianne Feaster

Author(s):  
Yunling Gao ◽  
Zorina S. Galis

Traditionally, much research effort has been invested into focusing on disease, understanding pathogenic mechanisms, identifying risk factors, and developing effective treatments. A few recent studies unraveling the basis for absence of disease, including cardiovascular disease, despite existing risk factors, a phenomenon commonly known as resilience, are adding new knowledge and suggesting novel therapeutic approaches. Given the central role of endothelial function in cardiovascular health, we herein provide a number of considerations that warrant future research and considering a paradigm shift toward identifying the molecular underpinnings of endothelial resilience.


Circulation ◽  
2015 ◽  
Vol 132 (9) ◽  
pp. 852-872 ◽  
Author(s):  
Merry L. Lindsey ◽  
Manuel Mayr ◽  
Aldrin V. Gomes ◽  
Christian Delles ◽  
D. Kent Arrell ◽  
...  

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