INSTI-BASED INITIAL ANTIRETROVIRAL THERAPY IN ADULTS WITH HIV, THE HIV OUTPATIENT STUDY, 2007-2018

2021 ◽  
Author(s):  
Stockton Mayer ◽  
Nabil Rayeed ◽  
Richard M. Novak ◽  
Jun Li ◽  
Frank J. Palella ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Outpatient Study

scholarly journals HIV RNA Suppression during and after Pregnancy among Women in the HIV Outpatient Study, 1996 to 2015

2018 ◽  
Vol 17 ◽  
pp. 232595741775225 ◽  
Author(s):  
Monita Patel ◽  
Ellen Tedaldi ◽  
Carl Armon ◽  
Steven Nesheim ◽  
Margaret Lampe ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Confidence Intervals ◽  
Viral Suppression ◽  
Hiv Rna ◽  
Hiv Viral Suppression ◽  
Observational Cohort ◽  
Estimated Risk ◽  
Risk Ratios ◽  
Outpatient Study

Objective: To examine HIV viral suppression during/after pregnancy. Design: Prospective observational cohort. Methods: We identified pregnancies from 1996 to 2015. We examined HIV RNA viral load (VL), VL suppression (≤500 copies/mL), and antiretroviral therapy (ART) status at pregnancy start, end, and 6 months postpartum. We estimated risk ratios (RRs) and 95% confidence intervals (CIs) for VL nonsuppression. Results: Among 253 pregnancies analyzed, 34.8% of women exhibited VL suppression at pregnancy start, 60.1% at pregnancy end, and 42.7% at 6 months postpartum. Median VL (log10 copies/mL) was 2.80 (interquartile range [IQR]: 1.40-3.85) at pregnancy start, 1.70 (IQR: 1.40-2.82) at pregnancy end, and 2.30 (IQR: 1.40-3.86) at postpartum. Risk of postpartum VL nonsuppression was also lower among women on ART and with VL suppression at pregnancy end (versus those not; adjusted RR = 0.30, 95% CI: 0.17-0.53). Conclusions: Maintaining VL suppression among US women remains a challenge, particularly during postpartum. Achieving VL suppression earlier during pregnancy benefits women subsequently.

Inadequate adherence to antiretroviral therapy and prevention in hospital and community sites in Burkina Faso and Mali

2005 ◽  
Author(s):  
Pascal Niamba ◽  
Souleymane A. G. Aboubacrine ◽  
Catherine Boileau ◽  
Maria-Victoria Zunzunegui ◽  
Vknh Kim Nguyen ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Burkina Faso
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