Short Communication: Risk Factors for Methicillin-Resistant Staphylococcus aureus Colonization Among HIV Patients at Hospital Admission

2013 ◽  
Vol 29 (5) ◽  
pp. 796-798 ◽  
Author(s):  
Linda K. Lee ◽  
Mar Kyaw Win ◽  
Meyyur A. Veeraraghavan ◽  
Chia Siong Wong ◽  
Angela L. Chow ◽  
...  
2010 ◽  
Vol 31 (05) ◽  
pp. 538-540 ◽  
Author(s):  
Laura McAllister ◽  
Robert P. Gaynes ◽  
David Rimland ◽  
John E. McGowan

Our case-control study sought to identify risk factors for colonization with methicillin-resistant Staphylococcus aureus (MRSA) at hospital admission among patients with no known healthcare-related risk factors. We found that patients whose most recent hospitalization occurred greater than 1 year before their current hospital admission were more likely to have MRSA colonization. In addition, both the time that elapsed since the most recent hospitalization and the duration of that hospitalization affected risk.


2021 ◽  
pp. 106002802110232
Author(s):  
Mariana G. Mallidi ◽  
Giles W. Slocum ◽  
Gary D. Peksa ◽  
Joshua M. DeMott

Background The high negative predictive value (NPV) of a negative nasal methicillin-resistant Staphylococcus aureus (MRSA) result in suspected MRSA pneumonia is well established; however, data are limited on the NPV of samples collected prior to hospital admission for critically ill patients. Objective To evaluate the predictive characteristics of MRSA nares screening performed prior to hospital admission in critically ill adult patients diagnosed with pneumonia. Methods A retrospective analysis was conducted in critically ill patients with pneumonia and MRSA nares screening within 60 days of respiratory culture. The primary outcome was NPV of MRSA nares for MRSA pneumonia using samples within 60 days compared to in-hospital respiratory cultures. A sensitivity analysis was performed for samples within 30 days. Secondary outcomes were prevalence, positive predictive value (PPV), sensitivity, specificity, and MRSA pneumonia risk factors. Results The NPV for MRSA nares screening collected prior to hospital admission was high at 98% (95% CI = 96%-99%) for samples collected within 60 days (n = 243) and 99% (95% CI: 94%-99.9%) for samples within 30 days (n = 119). Specificity for MRSA nares collected 60 days prior to admission (96%, 95% CI: 93-98) and 30 days (96%, 95% CI: 91%-99%) were both high. PPV and sensitivity were lower. Risk factors for MRSA pneumonia were similar. Conclusion and Relevance MRSA nares screening within 60 days of intensive care unit admission has a high NPV and specificity for MRSA pneumonia in critically ill patients and may be a powerful stewardship tool for avoidance of empirical anti-MRSA therapy.


2019 ◽  
Vol 8 (5) ◽  
pp. 631 ◽  
Author(s):  
Sung-Woo Choi ◽  
Jae Chul Lee ◽  
Jahyung Kim ◽  
Ji Eun Kim ◽  
Min Jung Baek ◽  
...  

Methicillin-resistant Staphylococcus aureus (MRSA) causes purulent skin and soft tissue infections as well as other life-threatening diseases. Recent guidelines recommend screening for MRSA at the time of admission. However, few studies have been conducted to determine the prevalence and risk factors for MRSA colonization. A prospective data collection and retrospective analysis was performed. MRSA screening tests were performed using nasal swabs in patients enrolled between January 2017 and July 2018. Demographic data, socio-economic data, medical comorbidities, and other risk factors for MRSA carriage were evaluated among 1577 patients enrolled in the study. The prevalence of MRSA nasal carriage was 7.2%. Univariate regression analysis showed that colonization with MRSA at the time of hospital admission was significantly related to patient age, body mass index, smoking, alcohol, trauma, recent antibiotic use, and route of hospital admission. Multiple logistic regression analysis for the risk factors for positive MRSA nasal carriage showed that being under- or overweight, trauma diagnosis, antibiotic use one month prior to admission, and admission through an emergency department were related to MRSA colonization. This study highlights the importance of a preoperative screening test for patients scheduled to undergo surgery involving implant insertion, particularly those at risk for MRSA.


SpringerPlus ◽  
2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Goyitom Gebremedhn ◽  
Tewelde Tesfay Gebremariam ◽  
Araya Gebreyesus Wasihun ◽  
Tsehaye Asmelash Dejene ◽  
Muthupandian Saravanan

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