Resistance Mutations in Subtype C HIV Type 1 Isolates from Indian Patients of Mumbai Receiving NRTIs Plus NNRTIs and Experiencing a Treatment Failure: Resistance to AR

2007 ◽  
Vol 23 (2) ◽  
pp. 335-340 ◽  
Author(s):  
Alaka Deshpande ◽  
Valérie Jauvin ◽  
Noel Magnin ◽  
Patricia Pinson ◽  
Muriel Faure ◽  
...  
Keyword(s):  
Treatment Failure ◽  
Resistance Mutations ◽  
Subtype C ◽  
Failure Resistance ◽  
Indian Patients ◽  
Hiv Type 1

scholarly journals Drug Resistance Mutations in Drug-Naive HIV Type 1 Subtype C-Infected Individuals from Rural Malawi

2011 ◽  
Vol 27 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Vijay Bansode ◽  
Zuzanna J. Drebert ◽  
Simon A.A. Travers ◽  
Emmanuel Banda ◽  
Anna Molesworth ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Resistance Mutations ◽  
Subtype C ◽  
Drug Resistance Mutations ◽  
Drug Naïve ◽  
Hiv Type 1

Analysis of RT Sequences of Subtype C HIV-Type 1 Isolates from Indian Patients at Failure of a First-Line Treatment According to Clinical and/or Immunological WHO Guidelines

2010 ◽  
Vol 26 (3) ◽  
pp. 343-350 ◽  
Author(s):  
Alaka Deshpande ◽  
Anne Cécile Jeannot ◽  
Marie Hélène Schrive ◽  
Linda Wittkop ◽  
Patricia Pinson ◽  
...  
Keyword(s):  
Line Treatment ◽  
Who Guidelines ◽  
Subtype C ◽  
First Line ◽  
Indian Patients ◽  
Hiv Type 1 ◽  
First Line Treatment

Characterization of HIV Type 1 Subtype C protease Gene: Selection of L63P Mutation in Protease Inhibitor-Naive Indian Patients

2011 ◽  
Vol 27 (11) ◽  
pp. 1249-1253 ◽  
Author(s):  
Ujjwal Neogi ◽  
Pravat Nalini Sahoo ◽  
Ravi Kumar ◽  
Ayesha De Costa ◽  
Anita Shet
Keyword(s):  
Protease Inhibitor ◽  
Gene Selection ◽  
Protease Gene ◽  
Subtype C ◽  
Indian Patients ◽  
Hiv Type 1 ◽  
Selection Of

scholarly journals Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
S. Sinha ◽  
H. Ahmad ◽  
R. C. Shekhar ◽  
N. Kumar ◽  
L. Dar ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Resistance Mutations ◽  
Subtype C ◽  
Hiv Drug Resistance ◽  
Northern India ◽  
Subtype B ◽  
Hiv Type 1 ◽  
Hiv 1

Objective. The increased use of antiretroviral therapy (ART) has reduced the morbidity and mortality associated with HIV, adversely leading to the emergence of HIV drug resistance (HIVDR). In this study we aim to evaluate the prevalence of HIVDR mutations in ART-naive HIV-1 infected patients from northern India.Design. Analysis was performed using Viroseq genotyping system based on sequencing of entire protease and two-thirds of the Reverse Transcriptase (RT) region ofpolgene.Results. Seventy three chronic HIV-1 infected ART naïve patients eligible for first line ART were enrolled from April 2006 to August 2008. In 68 patients DNA was successfully amplified and sequencing was done. 97% of HIV-1 strains belonged to subtype C, and one each to subtype A1 and subtype B. The overall prevalence of primary DRMs was 2.9% [2/68, 95% confidence interval (CI), 0.3%–10.2%]. One patient had a major RT mutation M184V, known to confer resistance to lamivudine, and another had a major protease inhibitor (PI) mutation D30N that imparts resistance to nelfinavir.Conclusion. Our study shows that primary HIVDR mutations have a prevalence of 2.9% among ART-naive chronic HIV-1 infected individuals.

Emergence of NNRTI Drug Resistance Mutations after Single-Dose Nevirapine Exposure in HIV Type 1 Subtype C-Infected Infants in India

2007 ◽  
Vol 23 (5) ◽  
pp. 682-685 ◽  
Author(s):  
Swarali N. Kurle ◽  
Raman R. Gangakhedkar ◽  
Sourav Sen ◽  
Shilpa S. Hayatnagarkar ◽  
Srikanth P. Tripathy ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Single Dose ◽  
Resistance Mutations ◽  
Subtype C ◽  
Drug Resistance Mutations ◽  
Single Dose Nevirapine ◽  
Hiv Type 1

scholarly journals Analysis of Nevirapine Resistance Mutations in Cloned HIV Type 1 Variants from HIV-Infected Ugandan Infants Using a Single-Step Amplification-Sequencing Method (AmpliSeq)

2008 ◽  
Vol 24 (9) ◽  
pp. 1209-1213 ◽  
Author(s):  
William Ian Towler ◽  
Jessica D. Church ◽  
James R. Eshleman ◽  
Mary Glenn Fowler ◽  
Laura A. Guay ◽  
...  
Keyword(s):  
Single Step ◽  
Resistance Mutations ◽  
Sequencing Method ◽  
Hiv Type 1 ◽  
Nevirapine Resistance

Genetic Linkage of Nevirapine Resistance Mutations in HIV Type 1 Seven Days after Single-Dose Nevirapine

2005 ◽  
Vol 21 (4) ◽  
pp. 319-324 ◽  
Author(s):  
Dana Jones ◽  
Neil Parkin ◽  
Sarah E. Hudelson ◽  
Laura A. Guay ◽  
Philippa Musoke ◽  
...  
Keyword(s):  
Single Dose ◽  
Genetic Linkage ◽  
Resistance Mutations ◽  
Single Dose Nevirapine ◽  
Hiv Type 1 ◽  
Nevirapine Resistance

scholarly journals Drug Resistance Mutations and Genetic Diversity in Patients Treated for HIV Type 1 Infection in Rural Care Centers in Togo

2016 ◽  
Vol 06 (03) ◽  
pp. 111-115
Author(s):  
Anoumou Dagnra ◽  
Abla Konou ◽  
Mounerou Salou ◽  
Pascal Kodah ◽  
Damobé Kombate ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Drug Resistance ◽  
Resistance Mutations ◽  
Drug Resistance Mutations ◽  
Hiv Type 1 ◽  
Rural Care
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