The HIV Type 1 Epidemic in Belarus: Predominance of Eastern European Subtype A Strains and Circulation of Subtype B Viruses

2005 ◽  
Vol 21 (9) ◽  
pp. 830-833 ◽  
Author(s):  
Natallia V. Lazouskaya ◽  
Vladimir F. Eremin ◽  
Karen W. Adema ◽  
Elena L. Gasich ◽  
Elly Baan ◽  
...  
Keyword(s):  
Eastern European ◽  
Subtype B ◽  
Hiv Type 1 ◽  
Subtype A ◽  
European Subtype

A Sudden Epidemic of HIV Type 1 among Injecting Drug Users in the Former Soviet Union: Identification of Subtype A, Subtype B, and NovelgagA/envB Recombinants

1998 ◽  
Vol 14 (8) ◽  
pp. 669-676 ◽  
Author(s):  
ALEKSEI BOBKOV ◽  
ELENA KAZENNOVA ◽  
LUDMILA SELIMOVA ◽  
MARINA BOBKOVA ◽  
TATYANA KHANINA ◽  
...  
Keyword(s):  
Soviet Union ◽  
Former Soviet Union ◽  
Drug Users ◽  
Injecting Drug Users ◽  
Subtype B ◽  
Hiv Type 1 ◽  
Subtype A

Genetic Analysis of Human Immunodeficiency Virus in Abidjan, Ivory Coast Reveals Predominance of HIV Type 1 Subtype A and Introduction of Subtype G

1999 ◽  
Vol 15 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Dennis L. Ellenberger ◽  
Danuta Pieniazek ◽  
John Nkengasong ◽  
Chi-Cheng Luo ◽  
Sushil Devare ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Genetic Analysis ◽  
Ivory Coast ◽  
Immunodeficiency Virus ◽  
Hiv Type 1 ◽  
Subtype A

scholarly journals Efficiencies of Four Versions of the AMPLICOR HIV-1 MONITOR Test for Quantification of Different Subtypes of Human Immunodeficiency Virus Type 1

1999 ◽  
Vol 37 (1) ◽  
pp. 110-116 ◽  
Author(s):  
K. Triques ◽  
J. Coste ◽  
J. L. Perret ◽  
C. Segarra ◽  
E. Mpoudi ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Viral Load ◽  
Pcr Primers ◽  
Load Test ◽  
Subtype C ◽  
Subtype B ◽  
Immunodeficiency Virus ◽  
Subtype A ◽  
Hiv 1

Three versions of a commercial human immunodeficiency virus (HIV) type 1 (HIV-1) load test (the AMPLICOR HIV-1 MONITOR Test versions 1.0, 1.0+, and 1.5; Roche Diagnostics, Branchburg, N.J.) were evaluated for their ability to detect and quantify HIV-1 RNA of different genetic subtypes. Plasma samples from 96 patients infected with various subtypes of HIV-1 (55 patients infected with subtype A, 9 with subtype B, 21 with subtype C, 2 with subtype D, 7 with subtype E, and 2 with subtype G) and cultured virus from 29 HIV-1 reference strains (3 of subtype A, 6 of subtype B, 5 of subtype C, 3 of subtype D, 8 of subtype E, 3 of subtype F, and 1 of subtype G) were tested. Detection of subtypes A and E was significantly improved with versions 1.0+ and 1.5 compared to that with version 1.0, whereas detection of subtypes B, C, D, and G was equivalent with the three versions. Versions 1.0, 1.0+, and 1.5 detected 65, 98, and 100% of the subtype A-infected samples from patients, respectively, and 71, 100, and 100% of the subtype E-infected samples from patients, respectively. Version 1.5 yielded a significant increase in viral load for samples infected with subtypes A and E (greater than 1 log10 HIV RNA copies/ml). For samples infected with subtype B, C, and D and tested with version 1.5, only a slight increase in viral load was observed (<0.5 log10). We also evaluated a prototype automated version of the test that uses the same PCR primers as version 1.5. The results with the prototype automated test were highly correlated with those of the version 1.5 test for all subtypes, but were lower overall. The AMPLICOR HIV-1 MONITOR Test, version 1.5, yielded accurate measurement of the HIV load for all HIV-1 subtypes tested, which should allow the test to be used to assess disease prognosis and response to antiretroviral treatment in patients infected with a group M HIV-1 subtype.

Phylogenetic Analysis of Multiple Heterosexual Transmission Events Involving Subtype B of HIV Type 1

2001 ◽  
Vol 17 (8) ◽  
pp. 689-695 ◽  
Author(s):  
Anna Hayman ◽  
Timothy Moss ◽  
Graham Simmons ◽  
Catherine Arnold ◽  
Edward C. Holmes ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Heterosexual Transmission ◽  
Subtype B ◽  
Hiv Type 1

scholarly journals Nucleotide and Amino Acid Polymorphisms at Drug Resistance Sites in Non-B-Subtype Variants of Human Immunodeficiency Virus Type 1

2004 ◽  
Vol 48 (8) ◽  
pp. 2993-2998 ◽  
Author(s):  
Dan Turner ◽  
Bluma Brenner ◽  
Daniela Moisi ◽  
Mervi Detorio ◽  
Raymond Cesaire ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Drug Resistance ◽  
Amino Acid ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Subtype B ◽  
Immunodeficiency Virus ◽  
Subtype A ◽  
Silent Substitutions

ABSTRACT We have compared nucleotide substitutions and polymorphisms at codons known to confer drug resistance in subtype B strains of human immunodeficiency virus type 1 (HIV-1) with similar substitutions in viruses of other subtypes. Genotypic analysis was performed on viruses from untreated individuals. Nucleotide and amino acid diversity at resistance sites was compared with a consensus subtype B reference virus. Among patients with non-subtype B infections, polymorphisms relative to subtype B were observed at codon 10 in protease (PR). These included silent substitutions (CTC→CTT, CTA, TTA) and an amino acid mutation, L10I. Subtype A viruses possessed a V179I substitution in reverse transcriptase (RT). Subtype G viruses were identified by silent substitutions at codon 181 in RT (TAT→TAC). Similarly, subtype A/G viruses were identified by a substitution at position 67 in RT (GAC→GAT). Subtype C was distinguished by silent substitutions at codons 106 (GTA→GTG) and 219 (AAA→AAG) in RT and codon 48 (GGG→GGA) in PR. Variations relative to subtype B were seen at RT position 215 (ACC→ACT) for subtypes A and A/E. These substitutions and polymorphisms reflect different patterns of codon usage among viruses of different subtypes. However, the existence of different subtypes may only rarely affect patterns of drug resistance-associated mutations.

Differential Prevalence of HIV Type 1 Subtype B and CRF01_AE among Different Sexual Transmission Groups in Tokyo, Japan, as Revealed by Subtype-Specific PCR

2003 ◽  
Vol 19 (11) ◽  
pp. 1057-1063 ◽  
Author(s):  
Shingo Kato ◽  
Yuki Saito ◽  
Rie Tanaka ◽  
Yoshiyuki Hiraishi ◽  
Naoto Kitamura ◽  
...  
Keyword(s):  
Sexual Transmission ◽  
Specific Pcr ◽  
Subtype B ◽  
Hiv Type 1

scholarly journals Molecular Epidemiology Reveals Long‐Term Changes in HIV Type 1 Subtype B Transmission in Switzerland

2010 ◽  
Vol 201 (10) ◽  
pp. 1488-1497 ◽  
Author(s):  
Roger D. Kouyos ◽  
Viktor von Wyl ◽  
Sabine Yerly ◽  
Jürg Böni ◽  
Patrick Taffé ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Subtype B ◽  
Long Term Changes ◽  
Hiv Type 1

scholarly journals Women Infected with HIV Type 1 Brazilian Variant, Subtype B (B'-GWGR Motif) Have Slower Progression to AIDS, Compared with Patients Infected with Subtype B (B-GPGR Motif)

2006 ◽  
Vol 43 (11) ◽  
pp. 1476-1481 ◽  
Author(s):  
A. de Brito ◽  
S. C. V. Komninakis ◽  
P. Novoa ◽  
R. M. d. Oliveira ◽  
L. A. M. Fonseca ◽  
...  
Keyword(s):  
Subtype B ◽  
Hiv Type 1 ◽  
Gpgr Motif
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