Crumbling Genome: The Impact of Deleterious Mutations on Humans. By Alexey S. Kondrashov. Hoboken (New Jersey): Wiley-Blackwell. $99.95 (paper). x + 281 p.; ill.; index. ISBN: 9781118952115. 2017.

2018 ◽  
Vol 93 (3) ◽  
pp. 274-274
Author(s):  
Joseph Lachance
2021 ◽  
Author(s):  
Ariel Thomas ◽  
Sönke Reiche ◽  
Christoph Clauser

<p>Offshore fresh groundwater reservoirs have been identified on continental shelves in several regions of the world. In many cases, sea-level change over geologic time-scales has been identified as a key factor in the emplacement of these freshwater systems. This numerical study analyzes a range of paleo-hydrogeological conditions on the New Jersey transect during the late Pleistocene, during which vast sections of the shelf were sub-aerially exposed. Coupled variable-density flow and heat transport simulations were conducted on a geologically representative 2D shelf model using SHEMAT-Suite. The model combines sequence stratigraphic interpretation of 2D depth migrated seismic lines and a stochastic facies distribution, with petrophysical properties derived from IODP Expedition 313 well data. The study considers a 60<sub></sub>000 year period of surface meteoric recharge, and the subsequent marine transgression from 12 000 years ago to present-day. A sensitivity analysis is conducted for key factors that influence offshore freshened groundwater emplacement during recharge phase: (1) topography-driven flow, and (2) permeability anisotropy. Systematically introducing anisotropy resulted in a 11 % – 31 % decrease in emplaced volume relative to the base-case. The results were analysed to determine whether the late Pleistocene sea-level lowstand drove enough freshwater emplacement that can explain the complex present-day observations. All of the simulated scenarios indicate that surface recharge lead to freshening of sediments across the entire transect during this period, even in case of high permeability anisotropy. The observations also suggest that the cyclical flushing and re-salinification of shelf sediments that takes place over glacial – interglacial cycles is an asymmetrical process, which favours storage of freshened pore fluid in the long run.</p>


2019 ◽  
Vol 28 (12) ◽  
pp. 1958-1967 ◽  
Author(s):  
Daniel Wiese ◽  
Antoinette M. Stroup ◽  
Amanda Crosbie ◽  
Shannon M. Lynch ◽  
Kevin A. Henry

Author(s):  
Devajyoti Deka ◽  
Michael Lahr ◽  
Thomas Marchwinski ◽  
Maia de la Calle

This study estimated the impact of spending by North Jersey Coast Line (NJCL) riders during summer weekends on the economies of the Jersey Shore communities known for beach-oriented recreational activities. The NJCL is a commuter rail line that provides many workers with access to their workplaces on weekdays throughout the year. The line also provides a large number of recreational visitors from New York City and other parts of New Jersey with direct access to the Jersey Shore communities on summer weekends. To estimate the economic benefits to the shore communities from spending by NJCL riders on summer weekends, this study used a software program (R/ECON) regional input–output (I-O) model developed by the Rutgers Economic Advisory Service of Rutgers University, New Brunswick, New Jersey. Visitor expenditure data from an onboard survey of NJCL riders were used as model inputs. The survey was conducted during the summer of 2013 and was completed by 2,241 riders returning from the shore area. The R/ECON I-O model provided estimates of economic benefits to the shore communities in terms of jobs, earnings, gross domestic product, state taxes, and local taxes. The model also generated return-on-investment multipliers for these variables. The study showed that the $14.8 million spent by NJCL riders on summer weekends in the shore communities generated approximately 225 annualized jobs, more than $9 million in earnings, and more than $1 million in state taxes. More than 80% of the economic benefit was generated by out-of-state visitor spending.


2020 ◽  
Vol 231 (4) ◽  
pp. e252-e253
Author(s):  
Miriam Y. Neufeld ◽  
Michael Poulson ◽  
Megan G. Janeway ◽  
Sabrina Elena Sanchez ◽  
Michael Siegel

2019 ◽  
Vol 38 (2) ◽  
pp. 232-275
Author(s):  
DAVIS A. YOUNG

ABSTRACT The first documented geology lectures at Princeton were given in 1825 by John Finch (circa 1790–circa 1835), an English visitor to the United States. In the 1830s, John Torrey (1796–1873) delivered a few geology and mineralogy lectures at the College of New Jersey (now Princeton University), but Joseph Henry (1797–1878), Professor of Natural Philosophy at the College of New Jersey from 1832 to 1848, introduced the first repeated geology course. In the 1830s, the College of New Jersey instituted a handful of short courses on topics outside of the regular curriculum. Geology was assigned to Henry, owing to his geological experience with Amos Eaton (1776–1842) along the recently opened Erie Canal. Henry taught geology for the first time in August 1841, repeated the course in 1843, 1846, and 1847, and probably also in 1844, 1845, 1850, and 1851. Henry typically focused on geophysical aspects of Earth, such as internal heat and Laplace's nebular hypothesis. He also discussed the geologic time scale from Primitive to Alluvium and Diluvium with descriptions of rock types and fossil content of each group. The final lecture was normally devoted to paleontology. Henry relied on Eaton and Edward Hitchcock (1793–1864) for much of his information and took advantage of published cross-sections to explain structural features. The content and timing of the various offerings is reconstructed from Henry's various lecture notes, dated correspondence, and three student notebooks. The impact of Henry's course on students, himself, and the Smithsonian Institution is evaluated.


2013 ◽  
Vol 58 (2) ◽  
pp. 274-284 ◽  
Author(s):  
Ruthie B. Birger ◽  
Timothy B. Hallett ◽  
Anushua Sinha ◽  
Bryan T. Grenfell ◽  
Sally L. Hodder

2010 ◽  
Vol 25 (2) ◽  
pp. 224-242 ◽  
Author(s):  
Joel M. Caplan

This study analyzed administrative data from the New Jersey State Parole Board to determine the extent to which victim and nonvictim input impacted parole release decisions. Positive and negative input, in both verbal and written forms, was studied for a representative sample of 820 parole-eligible adult inmates. Victim input was not found to be a significant predictor of parole release; measures of institutional behavior, crime severity, and criminal history were significant. Though insignificant, verbal input had a greater effect than written input. Results suggest that the impact of victim input is not generalizable across different types of offenders or across different paroling jurisdictions. It can no longer be assumed that victim rights laws and public participation at parole guarantee victim-desired outcomes.


PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e89221 ◽  
Author(s):  
Yara A. Halasa ◽  
Donald S. Shepard ◽  
Dina M. Fonseca ◽  
Ary Farajollahi ◽  
Sean Healy ◽  
...  

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