Comparison of the Microbiological Efficacy of Hydrogen Peroxide Vapor and Ultraviolet Light Processes for Room Decontamination

2012 ◽  
Vol 33 (5) ◽  
pp. 507-512 ◽  
Author(s):  
Nancy L. Havill ◽  
Brent A. Moore ◽  
John M. Boyce
Keyword(s):  
Hydrogen Peroxide ◽  
Prospective Observational Study ◽  
Biological Indicators ◽  
Line Of Sight ◽  
Geobacillus Stearothermophilus ◽  
Log Reduction ◽  
Before And After ◽  
The Mean ◽  
Mean Cycle ◽  
Hydrogen Peroxide Vapor

Objective.To compare the microbiological efficacy of hydrogen peroxide vapor (HPV) and ultraviolet radiation (UVC) for room decontamination.Design.Prospective observational study.Setting.500-bed teaching hospital.Methods.HPV and UVC processes were performed in 15 patient rooms. Five high-touch sites were sampled before and after the processes and aerobic colony counts (ACCs) were determined. Carrier disks with ~106Clostridium difficile (CD) spores and biological indicators (BIs) with 104 and 106Geobacillus stearothermophilus spores were placed in 5 sites before decontamination. After decontamination, CD log reductions were determined and BIs were recorded as growth or no growth.Results.93% of ACC samples that had growth before HPV did not have growth after HPV, whereas 52% of sites that had growth before UVC did not have growth after UVC (P < .0001). The mean CD log reduction was >6 for HPV and ~2 for UVC. After HPV 100% of the 104 BIs did not grow, and 22% did not grow after UVC, with a range of 7%–53% for the 5 sites. For the 106 BIs, 99% did not grow after HPV and 0% did not grow after UVC. Sites out of direct line of sight were significantly more likely to show growth after UVC than after HPV. Mean cycle time was 153 (range, 140–177) min for HPV and 73 (range, 39–100) min for UVC (P < .0001).Conclusion.Both HPV and UVC reduce bacterial contamination, including spores, in patient rooms, but HPV is significantly more effective. UVC is significantly less effective for sites that are out of direct line of sight.

A Head-to-Head Comparison of Hydrogen Peroxide Vapor and Aerosol Room Decontamination Systems

2011 ◽  
Vol 32 (9) ◽  
pp. 831-836 ◽  
Author(s):  
T. Holmdahl ◽  
P. Lanbeck ◽  
M. Wullt ◽  
M. H. Walder
Keyword(s):  
Hydrogen Peroxide ◽  
Cycle Time ◽  
New Technologies ◽  
Biological Indicators ◽  
The Other ◽  
Test Room ◽  
Cycle Times ◽  
Hydrogen Peroxide Vapor ◽  
In Vitro Comparison

Objective.New technologies have emerged in recent years for the disinfection of hospital rooms and equipment that may not be disinfected adequately using conventional methods. There are several hydrogen peroxide–based area decontamination technologies on the market, but no head-to-head studies have been performed.Design.We conducted a head-to-head in vitro comparison of a hydrogen peroxide vapor (HPV) system (Bioquell) and an aerosolized hydrogen peroxide (aHP) system (Sterinis).Setting.The tests were conducted in a purpose-built 136-m3test room.Methods.One HPV generator and 2 aHP machines were used, following recommendations of the manufacturers. Three repeated tests were performed for each system. The microbiological efficacy of the 2 systems was tested using 6-log Tyvek-pouchedGeobacillus stearo-thermophilusbiological indicators (BIs). The indicators were placed at 20 locations in the first test and 14 locations in the subsequent 2 tests for each system.Results.All BIs were inactivated for the 3 HPV tests, compared with only 10% in the first aHP test and 79% in the other 2 aHP tests. The peak hydrogen peroxide concentration was 338 ppm for HPV and 160 ppm for aHP. The total cycle time (including aeration) was 3 and 3.5 hours for the 3 HPV tests and the 3 aHP tests, respectively. Monitoring around the perimeter of the enclosure with a handheld sensor during tests of both systems did not identify leakage.Conclusion.One HPV generator was more effective than 2 aHP machines for the inactivation ofG. stearothermophilusBIs, and cycle times were faster for the HPV system.

Efficacy of an educational program for patients with pancreatic and biliary cancers, and their caregivers.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18221-e18221
Author(s):  
Reiko Makihara Ando ◽  
Chikako Doutani ◽  
Sayaka Kanehira ◽  
Mariko Nishizawa ◽  
Kyoko Hirata ◽  
...  
Keyword(s):  
Classroom Environment ◽  
Educational Program ◽  
Prospective Observational Study ◽  
Institutional Review Board ◽  
Informational Needs ◽  
Institutional Review ◽  
Distress Level ◽  
Before And After ◽  
Baseline Knowledge ◽  
The Mean

e18221 Background: We first introduced an educational program delivered in a classroom environment for patients with pancreatic and biliary cancers and their caregivers in 2007. Physicians, pharmacists, nurses, clinical psychotherapists, dietitians, and medical social workers attended and talked about their specialties. We conducted a prospective observational study from Jan. 2016 through Dec. 2016 to assess the efficacy of this educational program. Methods: This study was approved by our institutional review board and informed consent was obtained from all the participants. The 2-hour program included an overview of disease and information about treatment and management. The participants completed a questionnaire assessing their knowledge and including the Distress Thermometer both before and after the program. In addition, the participants completed a questionnaire regarding their satisfaction with the program to assess their informational needs. Results: Thirty-three patients and 50 caregivers were enrolled. Although no significant differences were seen in the mean baseline knowledge levels of the patients and caregivers, the mean baseline distress level was greater for the caregiver than for the patients. After attending the program, both the knowledge and distress levels were significantly improved for both the two groups. Regarding the satisfaction questionnaire, more than 90% of the participants reported being satisfied with the contents of the program and responded that the program was useful for their life. However, the percentage of respondents who reported being satisfied with hearing other participants’ stories was less than 40%. Conclusions: This study suggests that an educational program can improve knowledge and distress levels in patients and caregivers. We are planning to improve our program to further satisfy the needs of patients and caregivers, such as providing an opportunity to communicate with other participants, and to perform further evaluations.

scholarly journals Effect of Different Bleaching Methods on Optical Behaviors of CAD/CAM Ceramics

2021 ◽  
Vol 13 (4) ◽  
pp. 113-118
Author(s):  
Saeed Nikanjam ◽  
Samaneh Abbasi ◽  
Sara Khazaei
Keyword(s):  
Hydrogen Peroxide ◽  
Significant Influence ◽  
Color Change ◽  
Mean Value ◽  
Carbamide Peroxide ◽  
Mean Values ◽  
Before And After ◽  
Cad Cam ◽  
The Mean ◽  
Final Color

Background: The present study aimed to survey the influence of two different bleaching techniques on changes of color, translucency, and whiteness of the four CAD/CAM materials. Methods: The monolithic blocks of Vita Suprinity, Vita Enamic, IPS e.max CAD, and Katana Zirconia were sectioned to discs with thickness of 2 mm (n=30 / each group). Samples from each type of ceramic were assigned to three subgroups: 1) the 40% hydrogen peroxide for 20 minutes; 2) the 16% carbamide peroxide for three hours/day for 2 weeks; and 3) the control. Then CIELab coordinates of each sample were evaluated before and after the intervention by a spectrophotometer. Final color change (ΔE), Whiteness (ΔWI D), and Translucency Parameter (ΔTP) were calculated. Two-way ANOVA test was adopted to analyze the data (α=0.05). Results: Type of ceramic, bleaching subgroups, and interaction between them had a statistically significant influence on mean values of ΔE, ΔWID. The influence of bleaching subgroup on the mean value of ΔTP was also significant (P<0.001). Conclusions: Carbamide peroxide 16% for three hours/day and for two weeks caused the most considerable changes in final color, whiteness, and translucency of the all tested CAD/CAM materials. Maximum color change and whiteness were detected in the Vita Enamic, which were clinically unacceptable.

Hydrogen Peroxide Vapor Decontamination in a Patient Room Using Feline Calicivirus and Murine Norovirus as Surrogate Markers for Human Norovirus

2016 ◽  
Vol 37 (5) ◽  
pp. 561-566 ◽  
Author(s):  
Torsten Holmdahl ◽  
Mats Walder ◽  
Nathalie Uzcátegui ◽  
Inga Odenholt ◽  
Peter Lanbeck ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Cell Culture ◽  
Tissue Culture ◽  
Feline Calicivirus ◽  
Murine Norovirus ◽  
Patient Room ◽  
Human Norovirus ◽  
Log Reduction ◽  
Infective Dose ◽  
Hydrogen Peroxide Vapor

OBJECTIVETo determine whether hydrogen peroxide vapor (HPV) could be used to decontaminate caliciviruses from surfaces in a patient room.DESIGNFeline calicivirus (FCV) and murine norovirus (MNV) were used as surrogate viability markers to mimic the noncultivable human norovirus. Cell culture supernatants of FCV and MNV were dried in triplicate 35-mm wells of 6-well plastic plates. These plates were placed in various positions in a nonoccupied patient room that was subsequently exposed to HPV. Control plates were positioned in a similar room but were never exposed to HPV.METHODSVirucidal activity was measured in cell culture by reduction in 50% tissue culture infective dose titer for FCV and by both 50% tissue culture infective dose titer and plaque reduction for MNV.RESULTSNeither viable FCV nor viable MNV could be detected in the test room after HPV treatment. At least 3.65 log reduction for FCV and at least 3.67 log reduction for MNV were found by 50% tissue culture infective dose. With plaque assay, measurable reduction for MNV was at least 2.85 log units.CONCLUSIONSThe successful inactivation of both surrogate viruses indicates that HPV could be a useful tool for surface decontamination of a patient room contaminated by norovirus. Hence nosocomial spread to subsequent patients can be avoided.Infect Control Hosp Epidemiol 2016;37:561–566

Hydrogen Peroxide Vapor: A Novel Method for the Environmental Control of Lactococcal Bacteriophage†

2009 ◽  
Vol 72 (2) ◽  
pp. 412-414 ◽  
Author(s):  
JONATHAN A. OTTER ◽  
ANDREA BUDDE-NIEKIEL
Keyword(s):  
Hydrogen Peroxide ◽  
Stainless Steel ◽  
Environmental Control ◽  
Log Reduction ◽  
Novel Method ◽  
Industrial Settings ◽  
Hydrogen Peroxide Vapor

Bacteriophage contamination can be problematic, especially in industrial settings. We examined the in vitro efficacy of hydrogen peroxide vapor (HPV) for the inactivation of two lactococcal bacteriophages dried onto stainless steel discs. A more than 6-log reduction was achieved on both bacteriophages compared with unexposed controls by 50 min of HPV exposure in an isolator. HPV might be useful for the environmental control of bacteriophages.

scholarly journals Comparison of the effectiveness of manual cleaning, hydrogen peroxide vapor and ultraviolet-c in disinfection of hospital equipment

2020 ◽  
Vol 39 (3) ◽  
pp. 66-84 ◽  
Author(s):  
Yosra Sedaghat ◽  
Seifollah Gholampour ◽  
Farhad Tabatabai Ghomshe
Keyword(s):  
Hydrogen Peroxide ◽  
Complete Coverage ◽  
Hospital Beds ◽  
Before And After ◽  
Ultraviolet C ◽  
Pressure Meter ◽  
Uv C ◽  
Hospital Equipment ◽  
Hydrogen Peroxide Vapor ◽  
Number Of Bacteria

Hospitals are the focus of many infections which cause the intensification of the patients’ illness and even their death. The number of bacteria on various hospital equipment was counted before and after being disinfected with manual cleaning (MC), hydrogen peroxide vapour (HPV) and ultraviolet-C (UV-C). The effectiveness of disinfection of hospital beds in intensive care unit (ICU) using the three methods MC, HPV and UV-C has been 66.67%, 100% and 50%, respectively. Hence, the effectiveness of HPV method in the disinfection of this unit has been higher than others. The effectiveness of otoscope disinfection in the ICU and blood pressure meter in the operating room with three methods of MC, HPV and UV-C has been 0%, 50% and 100%, respectively. So, for disinfecting these small outfits, UV-C method has proven to be the best one. In case of programming, the correct move of portable UV-Cs for complete coverage of massive equipment, disinfection with UV-C method may be considered more effective than other methods.

Sign in / Sign up

Export Citation Format

Share Document