scholarly journals Acute Necrotizing Encephalopathy Progressing to Brain Death in a Pediatric Patient with Novel Influenza A (H1N1) Infection

2010 ◽  
Vol 50 (8) ◽  
pp. e50-e52 ◽  
Author(s):  
Alexandra Martin ◽  
Erin Parrish Reade
Neurology ◽  
2011 ◽  
Vol 77 (21) ◽  
pp. e121-e121 ◽  
Author(s):  
A. Spalice ◽  
F. Del Balzo ◽  
F. Nicita ◽  
L. Papetti ◽  
F. Ursitti ◽  
...  

2010 ◽  
Vol 68 (1) ◽  
pp. 111-114 ◽  
Author(s):  
Paolo Mariotti ◽  
Raffaele Iorio ◽  
Giovanni Frisullo ◽  
Domenico Plantone ◽  
Raffaella Colantonio ◽  
...  

2019 ◽  
Vol 66 (2) ◽  
pp. 228-230
Author(s):  
Mili Thomas ◽  
Kamala Swarnam ◽  
Gopika Sekhar Remadevi ◽  
A Marthanda Pillai

Abstract Four-year old boy was admitted with acute onset of fever with seizures and altered sensorium. His mother had history of contact with influenza A H1N1 virus (H1N1) infection. Blood counts, electrolytes, blood sugar and ammonia were normal. Liver enzymes were mildly elevated. CSF study showed elevated protein, normal sugar and no pleocytosis. Cerebrospinal fluid (CSF) viral panel was negative. Magnetic resonance imaging brain was suggestive of acute necrotizing encephalopathy. His throat swab and sputum polymerase chain reaction was positive for H1N1. He was managed with ventilation, intravenous steroids and other supportive measures. At discharge his sensorium improved but had neurological sequelae. We are presenting this case as this is a very rare complication of H1N1 infection with high rate of mortality. Early supportive measures and steroids/intravenous immunoglobulin may save the patient.


2013 ◽  
Vol 37 (2) ◽  
pp. 286 ◽  
Author(s):  
Ki Jung Kim ◽  
Eun Sook Park ◽  
Hyun Jung Chang ◽  
Miri Suh ◽  
Dong-Wook Rha

2019 ◽  
Vol 13 (01) ◽  
pp. 83-86 ◽  
Author(s):  
Sevliya Öcal Demir ◽  
Serkan Atıcı ◽  
Eda Kepenekli Kadayifci ◽  
Gülşen Akkoç ◽  
Nurhayat Yakut ◽  
...  

Influenza is a generally self-limited infection agent that only rarely causes severe complications. To increase awareness about its serious complications, we report three cases of influenza A (H1N1) infection complicated with hemolytic uremic syndrome, myocarditis and acute necrotizing encephalopathy. In all three cases, nasopharyngeal samples confirmed influenza A (H1N1) infection by antigen test and multiplex PCR detection. The first case, a 3-year-old girl, had respiratory distress, anemia, thrombocytopenia and renal failure at admission, and was diagnosed with hemolytic uremic syndrome. Supportive treatment and oseltamivir did not prevent the development of chronic renal failure. The second case, a 5-year-old girl admitted with lethargia and flu-like symtoms and was diagnosed with myocarditis and cardiogenic shock. Oseltamivir and supportive treatment including extra-corporeal membrane oxygenation (ECMO) failed. She died on the 3rd day of admission. The third case, a 21-month-old boy, presented with decreased level of consciousness and was diagnosed with acute necrotizing encephalopathy with the aid of cranial magnetic resonance imagining (MRI). He was discharged without any neurological sequelae three weeks after admission. It should be kept in mind that influenza virus does not always cause a self-limited flu. Multidisciplinary management, early diagnosis and antiviral treatment are critical for the disease and to prevent its life-threatening complications.


2010 ◽  
Vol 69 (1) ◽  
pp. 24 ◽  
Author(s):  
Chang Hoon Han ◽  
Yu Kyung Hyun ◽  
Yu Ri Choi ◽  
Na Young Sung ◽  
Yoon Seon Park ◽  
...  

2010 ◽  
Vol 29 (8) ◽  
pp. 782-783 ◽  
Author(s):  
Katalin Koranyi ◽  
Dustin Yontz ◽  
Zachary Rohrer ◽  
Amy Leber ◽  
Octavio Ramilo

1970 ◽  
Vol 8 (4) ◽  
pp. 84-90
Author(s):  
Musa Mohd. Nordin

During the 1918 Spanish Flu pandemic, often described as the most devastating epidemic in recorded history, 1 in 5 person was infected and an estimated 50 million lives were lost. The disease was so widespread and pervasive that even the children had a tune which they skipped rope to: I had a little bird, its name was Enza, I opened the window and In-Flu-Enza. DOI: 10.3329/bjms.v8i4.4705 Bangladesh Journal of Medical Sciences Vol.8(4); October 2009 pp84-90


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