scholarly journals Regulatory T Cells Modulate Th17 Responses in Patients with Positive Tuberculin Skin Test Results

2010 ◽  
Vol 201 (1) ◽  
pp. 20-31 ◽  
Author(s):  
Subash Babu ◽  
Sajid Q. Bhat ◽  
N. Pavan Kumar ◽  
V. Kumaraswami ◽  
Thomas B. Nutman
2018 ◽  
Vol 39 (6) ◽  
pp. 750-752 ◽  
Author(s):  
Jeffrey M. Collins ◽  
Mary Hunter ◽  
Wanda Gordon ◽  
Russell R. Kempker ◽  
Henry M. Blumberg ◽  
...  

Following large declines in tuberculosis transmission the United States, large-scale screening programs targeting low-risk healthcare workers are increasingly a source of false-positive results. We report a large cluster of presumed false-positive tuberculin skin test results in healthcare workers following a change to 50-dose vials of Tubersol tuberculin.Infect Control Hosp Epidemiol 2018;39:750–752


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Shweta Agarwal ◽  
Siddharth Kumar Das ◽  
Girdhar G. Agarwal ◽  
Ragini Srivastava

Tuberculin skin test has been used as an indicator of latent tuberculosis in patients with Rheumatoid Arthritis (RA) before administration of biologicals. Effect of Disease modifying antirheumatic drugs (DMARDs) and steroids on the result of tuberculin skin test (TST) may have important implications in interpretation of results of this test.Objectives. To find the prevalence of positive TST in rheumatoid patients and the effect of standard treatment on the results of TST.Method. In this cross-sectional study two hundred and fifty patients of RA above 18 years of age, classified using 1987 ACR criteria for RA, were enrolled from rheumatology outdoor. Demographics, disease activity, disease duration, and therapy were recorded. All patients underwent TST.Results. Fifty-one (20.4%) patients were found to be tuberculin positive. Tuberculin positivity was not affected by MTX intake but it was significantly low in patients with recent steroid intake as compared to patients who had not taken steroids in last 3 months (3% versus 25%,P= 0.002).Conclusion. Prevalence of tuberculin positivity in patients with RA was found to be low. Results were not affected by methotrexate; however tuberculin skin test results in patients with recent use of steroids are likely to be negative.


2008 ◽  
Vol 41 (4) ◽  
pp. 416-418 ◽  
Author(s):  
Florian H. Pilsczek ◽  
Stefan H.E. Kaufmann

Latent tuberculosis was studied in a research laboratory. A prevalence of positive tuberculin skin test results (> 15mm) of 20% was found and the main predictors were place of birth in a foreign country with high prevalence of tuberculosis and a history of contact with patients with untreated active tuberculosis.


2008 ◽  
Vol 11 (Suppl 1) ◽  
pp. P259
Author(s):  
NT Teeratakulpisarn ◽  
SP Phositlimakul ◽  
PS Suwanmala ◽  
CW Wongsuthipol ◽  
TP Pankam ◽  
...  

2009 ◽  
Vol 30 (1) ◽  
pp. 80-82 ◽  
Author(s):  
Thomas G. Fraser ◽  
Joan Kowalczyk ◽  
Steven Schmitt ◽  
Jill Bernstein ◽  
Paul Terpeluk ◽  
...  

We describe a healthcare worker with a previously positive tuberculin skin test result who developed active tuberculosis. An investigation revealed 280 potential contacts, 3 of whom had positive tuberculin skin test results. Our experience demonstrates the potential benefits of therapy for latent tuberculosis infection as a component of a tuberculosis-control program.


CHEST Journal ◽  
2014 ◽  
Vol 145 (3) ◽  
pp. 612-617 ◽  
Author(s):  
John L. Johnson ◽  
Hendrik Geldenhuys ◽  
Bonnie A. Thiel ◽  
Asma Toefy ◽  
Sara Suliman ◽  
...  

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