scholarly journals Long‐Term Immunity and Protection against Herpes Simplex Virus Type 2 in the Murine Female Genital Tract after Mucosal but Not Systemic Immunization

1998 ◽  
Vol 177 (5) ◽  
pp. 1155-1161 ◽  
Author(s):  
W. Scott Gallichan ◽  
Kenneth L. Rosenthal
2014 ◽  
Vol 8 (1) ◽  
pp. 115-126 ◽  
Author(s):  
C M Posavad ◽  
L Zhao ◽  
D E Mueller ◽  
C E Stevens ◽  
M L Huang ◽  
...  

2014 ◽  
Vol 192 (11) ◽  
pp. 5074-5082 ◽  
Author(s):  
Brett Shannon ◽  
Tae Joon Yi ◽  
Jamie Thomas-Pavanel ◽  
Lisungu Chieza ◽  
Praseedha Janakiram ◽  
...  

2005 ◽  
Vol 79 (17) ◽  
pp. 11537-11540 ◽  
Author(s):  
Gregg N. Milligan ◽  
Michael G. Meador ◽  
Chin-Fun Chu ◽  
Christal G. Young ◽  
Talitha L. Martin ◽  
...  

ABSTRACT The tissue sites of long-term herpes simplex virus type 2 (HSV-2)-specific antibody production in mice and guinea pigs were identified. In addition to secondary lymphoid tissue and bone marrow, HSV-specific plasma cells were detected in spinal cords of mice up to 10 months after intravaginal inoculation with a thymidine kinase-deficient HSV-2 strain and in lumbosacral ganglia and spinal cords of guinea pigs inoculated with HSV-2 strain MS. The long-term retention of virus-specific plasma cells in the peripheral and central nervous systems following HSV infection may be important for resistance to reinfection of neuronal tissues or may play a role in modulation of reactivation from latency.


1987 ◽  
Vol 93 (1-2) ◽  
pp. 51-68 ◽  
Author(s):  
M. R. McDermott ◽  
P. Leslie ◽  
J. Brais ◽  
Gudrun C. Goettsche ◽  
M. J. Evelegh ◽  
...  

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