scholarly journals Clostridium sordellii Infection: Epidemiology, Clinical Findings, and Current Perspectives on Diagnosis and Treatment

2006 ◽  
Vol 43 (11) ◽  
pp. 1436-1446 ◽  
Author(s):  
M. J. Aldape ◽  
A. E. Bryant ◽  
D. L. Stevens
1990 ◽  
Vol 80 (6) ◽  
pp. 289-297
Author(s):  
PK Geistler ◽  
KG Canter ◽  
NA Staley

The authors present a review of amyloidosis and its classification and clinical presentations. They also discuss its diagnosis and treatment, and present a case of amyloid deposition in the plantar weightbearing aspects of the feet, which exemplifies the classic clinical findings.


2005 ◽  
Vol 41 (2) ◽  
pp. 104-109 ◽  
Author(s):  
Sarah L. Naidoo ◽  
Debbie L. Campbell ◽  
Lisa M. Miller ◽  
Andrea Nicastro

Necrotizing fasciitis is a rapidly spreading, bacterial, soft-tissue infection reported in both humans and dogs. A review of the pathophysiology, clinical findings, diagnosis, and treatment of necrotizing fasciitis is presented, with the goal of familiarizing veterinarians with this uncommon but potentially fatal condition. A case report highlighting the fulminant course of this disease is also included.


Aggressive retinopathy of prematurity (AP-ROP) has subtle clinical findings that may preclude early diagnosis and treatment. Premature infants with AP-ROP have a progressive clinical course and may benefit from early laser treatment. Although subjective in nature, plus disease, and any posterior pole changes especially at the border of the vascular and avascular retina should be carefully evaluated, keeping AP-ROP in mind in especially high-risk preterm babies.


Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common ischemic optic neuropathy and the most common type of optic neuropathy after glaucoma. It is a vascular optic neuropathy that is not related to inflammation, demyelinization, and compression and it is the most common visual loss due to optic nerve involvement. While incidence between the ages of 55-65 is increasing; factors affecting the etiopathogenesis and development of NAION and its treatment have not been clarified yet. This article summarizes the literature on the pathogenesis, clinical findings, diagnosis, and treatment of NAION.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Alessandro Villa ◽  
Stefano Castiglioni ◽  
Alessandro Peretti ◽  
Marco Omodei ◽  
B. Giovanni Ferrieri ◽  
...  

The aim of this longitudinal study is to present data from 76 female patients treated with bisphosphonates (BPs) for postmenopausal osteoporosis and referred to the Unit of Oral Diagnosis and Day Surgery of the University of Milano for diagnosis and treatment. All patients received a thorough oral examination. The diagnosis of osteonecrosis of the jaw bone (ONJ) was made from radiographic and clinical findings. 9% of individuals had BRONJ at first visit. Patients with dental or periodontal abscess were significantly more likely to develop BRONJ (OR: 2.9, 95% CI 0.5–15.9). Patients with osteoporosis receiving BPs may develop BRONJ, especially in the presence of an active infectious process in the mouth. Clinicians should carefully follow up on individuals receiving bisphosphonates therapy to avoid the occurrence of osteonecrotic lesions.


Immüne recovery uveitis (IRU) is the most common form of immune reconstitution inflammatory syndrome in human immunodeficiency virus (HIV) infected patients with cytomegalovirus (CMV) retinitis who are receiving highly active antiretroviral therapy (HAART) therapy. In patients with CMV retinitis in the HAART era, immune recovery may be associated with a greater number of inflammatory complications, including vitritis, macular edema, epiretinal membrane formation, papillitis, and iris synechiae. Given the range of ocular manifestations of HIV, routine ocular examinations and screening carefully for visual loss are recommended in patients with CD4 counts <50 cells/μL. With the increasing longevity of these patients due to the use of HAART, treatment of IRU may become an issue in the future. Uveitis has been associated with a number of systemic, intravitreal, and topical medications, and may also occur after vaccination and the use of other substances. However, drug-induced uveitis is a relatively rare event. Only a few drugs have been proven to cause uveitis, whereas many others may not represent a direct cause-and-effect relationship. Anterior uveitis is the most common clinical presentation and therefore, patients with new-onset anterior uveitis should be asked whether they have recently started any new medications. These patients need to undergo the same diagnostic protocol followed for any uveitis case. Drug-induced uveitis is almost always reversible within weeks of cessation of the medication and the institution of topical treatment of the inflammation. The clinical findings, diagnosis, and treatment of IRU and drug-induced uveitis are presented in this current study


Uveitis is the inflammation of the anterior, intermediate, or posterior uvea, the pigmented part of the eye.  Uveitis can be infectious or non-infectious presented as autoimmune and immune-mediated. Non-infectious uveitis is the most common type of uveitis. It can be idiopathic or secondary to systemic diseases. Differential diagnosis is important, if early diagnosis and treatment are not applied, permanent eye damage can occur. In this review, an overview of non-infectious uveitis is examined with the mechanism, immunopathology, and classification.


ESC CardioMed ◽  
2018 ◽  
pp. 1715-1720
Author(s):  
Isidre Vilacosta ◽  
Carmen Olmos

Nowadays, despite improvements in diagnosis and treatment, infective endocarditis remains associated with high mortality and severe complications. When assessing the prognosis of patients with endocarditis, three different clinical periods are distinguished: prognostic assessment at admission, early risk reassessment during the first week after the beginning of antibiotics, and short- and long-term prognosis after discharge. The three cornerstones for assessing patients’ prognosis can be obtained from clinical findings, echocardiography, and blood cultures. Analytic parameters such as thrombocytopenia may also help to stratify risk.


2016 ◽  
Vol 06 (02) ◽  
pp. 085-087
Author(s):  
Ahmed S. Elagwany ◽  
Nehal Anas

AbstractEndometritis and toxic shock syndrome associated with Clostridium sordellii havepreviously been reported after childbirth and, in one case, after medical abortion. Clinical findings included tachycardia, hypotension, edema, hemoconcentration, profound leukocytosis, and absence of fever. We describe a young woman who developed Clostridium sordellii toxicshock syndrome after having had an abortion surgically evacuated five days before admission to our hospital. Although the patient was aggressively treated, death occurred <3 days after admission. It is hoped that very early recognition of this disease will decrease the mortality associated with this rarely reported ailment.


Candidiasis is a major cause of morbidity and mortality. Earlier identification and treatment of candidemia has led to a decline in the incidence of ocular candidiasis in recent years. Ocular candidiasis shows a progression from chorioretinitis to endophthalmitis and may cause significant vision loss. Therefore emphasis should be given to early detection and treatment of candidemia patients and appropriate screening programs for ocular involvement.


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