scholarly journals Evaluation of Serum Levels of Interleukin (IL)–6, IL‐10, and Tumor Necrosis Factor–α in Patients with Crimean‐Congo Hemorrhagic Fever

2006 ◽  
Vol 193 (7) ◽  
pp. 941-944 ◽  
Author(s):  
Onder Ergonul ◽  
Semra Tuncbilek ◽  
Nurcan Baykam ◽  
Aysel Celikbas ◽  
Basak Dokuzoguz
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Hemorrhagic Fever ◽  
Serum Levels ◽  
Crimean Congo Hemorrhagic Fever ◽  
Factor Α ◽  
Necrosis Factor

Tumor necrosis factor α and interferon γ genes polymorphisms and serum levels in pancreatic adenocarcinoma

Neoplasma ◽  
2009 ◽  
Vol 56 (1) ◽  
pp. 56-62 ◽  
Author(s):  
R. Talar-Wojnarowska ◽  
A. Gasiorowska ◽  
B. Smolarz ◽  
H. Romanowicz-Makowska ◽  
A. Kulig ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Pancreatic Adenocarcinoma ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Interferon Γ ◽  
Factor Α ◽  
Necrosis Factor

Serum levels of interleukin 6 and tumor necrosis factor-α in hyperthyroid patients before and after propylthiouracil treatment

1995 ◽  
Vol 132 (6) ◽  
pp. 668-672 ◽  
Author(s):  
Ismail Çelik ◽  
Sema Akalin ◽  
Tomris Erbaş
Keyword(s):  
Tumor Necrosis Factor ◽  
Interleukin 6 ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Graves Disease ◽  
Tnf Α ◽  
Factor Α ◽  
Hyperthyroid Patients ◽  
Necrosis Factor

Çelik I, Akalin S, Erbaş T. Serum levels of interleukin 6 and tumor necrosis factor-α in hyperthyroid patients before and after propylthiouracil treatment. Eur J Endocrinol 1995;132:668–72. ISSN 0804–4643 Contrary to the usual inhibitory role of tumor necrosis factor-α (TNF-α) thyroid metabolism, it also has specific stimulatory effects in autoimmune thyroid disorders, including induction of HLA class II antigen-presenting cell—T cell interaction. Despite high intrathyroidal concentrations, various studies were not able to demonstrate high serum levels of TNF-α in patients with Graves' disease. To investigate this discrepancy we determined TNF-α and interleukin 6 (IL-6) levels in 25 hyperthyroid patients who responded to propylthiouracil treatment (16 with Graves' disease and nine with toxic multinodular goiter) and compared them with the levels found in euthyroid patients with simple diffuse goiter (n = 15) and normal healthy controls (n = 15). Median IL-6 levels were high in both Graves' disease and toxic multinodular goiter patients before propylthiouracil treatment (23 and 26.5 pg/ml, respectively). After restoring euthyroidism there was a statistically significant decline to near-normal levels (3 and 10 pg/ml, respectively). On the other hand, median serum TNF-α levels were high only in Graves' disease patients (20 pg/ml) and could not be normalized with antithyroid medication (20 pg/ml) compared to that of controls (5 pg/ml). Tumor necrosis factor-α, but not IL-6, was found to be high in the sera of Graves' disease patients when euthyroid, which may be due to an ongoing antigen–antibody interaction, a feature of autoimmune attack. It remains to be determined whether the degree of TNF-α and/or IL-6 elevation will be a predictor of disease recurrence. Ismail Çelik, Section of Oncology, Dept. of Medicine, Hacettepe University Institute of Oncology, Ankara 06100, Turkey

scholarly journals Serum Levels of Tumor Necrosis Factor-α Are Increased in Obese Patients with Noninsulin-Dependent Diabetes Mellitus1

1998 ◽  
Vol 83 (3) ◽  
pp. 859-862 ◽  
Author(s):  
Akira Katsuki ◽  
Yasuhiro Sumida ◽  
Shuichi Murashima ◽  
Kazuya Murata ◽  
Yoshihiro Takarada ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Serum Levels ◽  
Obese Patients ◽  
Factor Α ◽  
Necrosis Factor
Sign in / Sign up

Export Citation Format

Share Document