scholarly journals Induction of Potent Th1‐Type Immune Responses from a Novel DNA Vaccine for West Nile Virus New York Isolate (WNV‐NY1999)

2001 ◽  
Vol 184 (7) ◽  
pp. 809-816 ◽  
Author(s):  
Joo‐Sung Yang ◽  
J. Joseph Kim ◽  
Daniel Hwang ◽  
Andrew Y. Choo ◽  
Kesen Dang ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Immune Responses ◽  
Dna Vaccine ◽  
West Nile

scholarly journals DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus

2003 ◽  
Vol 100 (18) ◽  
pp. 10460-10464 ◽  
Author(s):  
R. A. Hall ◽  
D. J. Nisbet ◽  
K. B. Pham ◽  
A. T. Pyke ◽  
G. A. Smith ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Dna Vaccine ◽  
Full Length ◽  
West Nile ◽  
Virus Rna

scholarly journals Current Understanding of West Nile Virus Clinical Manifestations, Immune Responses, Neuroinvasion, and Immunotherapeutic Implications

Pathogens ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 193 ◽  
Author(s):  
Fengwei Bai ◽  
E. Ashley Thompson ◽  
Parminder J. S. Vig ◽  
A. Arturo Leis
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Immune Responses ◽  
Clinical Manifestations ◽  
The United States ◽  
Current Understanding ◽  
Therapeutic Interventions ◽  
Clinical Practices ◽  
West Nile ◽  
Neuroinvasive Disease

West Nile virus (WNV) is the most common mosquito-borne virus in North America. WNV-associated neuroinvasive disease affects all ages, although elderly and immunocompromised individuals are particularly at risk. WNV neuroinvasive disease has killed over 2300 Americans since WNV entered into the United States in the New York City outbreak of 1999. Despite 20 years of intensive laboratory and clinical research, there are still no approved vaccines or antivirals available for human use. However, rapid progress has been made in both understanding the pathogenesis of WNV and treatment in clinical practices. This review summarizes our current understanding of WNV infection in terms of human clinical manifestations, host immune responses, neuroinvasion, and therapeutic interventions.

scholarly journals Pesticide Spraying for West Nile Virus Control and Emergency Department Asthma Visits in New York City, 2000

2004 ◽  
Vol 112 (11) ◽  
pp. 1183-1187 ◽  
Author(s):  
Adam M. Karpati ◽  
Mary C. Perrin ◽  
Tom Matte ◽  
Jessica Leighton ◽  
Joel Schwartz ◽  
...  
Keyword(s):  
Emergency Department ◽  
New York ◽  
New York City ◽  
West Nile Virus ◽  
York City ◽  
West Nile ◽  
Virus Control

scholarly journals DNA Vaccine for West Nile Virus Infection in Fish Crows (Corvus ossifragus)

2003 ◽  
Vol 9 (9) ◽  
pp. 1077-1081 ◽  
Author(s):  
Michael J. Turell ◽  
Michel Bunning ◽  
George V. Ludwig ◽  
Brian Ortman ◽  
Jeff Chang ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Virus Infection ◽  
Dna Vaccine ◽  
West Nile Virus Infection ◽  
West Nile

scholarly journals West Nile Virus Population Structure, Injury, and Interferon-Stimulated Gene Expression in the Brain From a Fatal Case of Encephalitis

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Nathan D. Grubaugh ◽  
Aaron Massey ◽  
Katherine D. Shives ◽  
Mark D. Stenglein ◽  
Gregory D. Ebel ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Immune Responses ◽  
Selection Pressure ◽  
Fatal Case ◽  
Brain Regions ◽  
Human Case ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
West Nile ◽  
Acute Encephalitis

Abstract Background.  West Nile virus (WNV) infection in humans can result in severe, acute encephalitis typically involving subcortical gray matter brain regions. West Nile virus replication within specific human brain regions from a human case of acute encephalitis has not been studied. Methods.  We describe a fatal case of WNV encephalitis in which we obtained tissue from specific brain regions at autopsy to evaluate viral-host interactions using next-generation sequencing and immunohistochemistry analysis. Results.  We found that WNV populations in the injured subcortical brain regions exhibited increased amino acid variation and increased expression of specific interferon genes compared with cortical tissues despite similar viral burden. Conclusions.  These observational, patient-based data suggest that neuronal injury and the strength of viral selection pressure may be associated with the level of the innate immune responses. Further studies in human and animal models evaluating the role of innate immune responses on injury patterns and viral selection pressure are needed.

scholarly journals Immune responses to an attenuated West Nile virus NS4B-P38G mutant strain

Vaccine ◽  
2011 ◽  
Vol 29 (29-30) ◽  
pp. 4853-4861 ◽  
Author(s):  
Thomas Welte ◽  
Guorui Xie ◽  
Jason A. Wicker ◽  
Melissa C. Whiteman ◽  
Li Li ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Immune Responses ◽  
Mutant Strain ◽  
West Nile

scholarly journals Mosquito Surveillance and Polymerase Chain Reaction Detection of West Nile Virus, New York State

2001 ◽  
Vol 7 (4) ◽  
pp. 643-649 ◽  
Author(s):  
Dennis J. White ◽  
Laura D. Kramer ◽  
P. Bryon Backenson ◽  
Gary Lukacik ◽  
Geraldine Johnson ◽  
...  
Keyword(s):  
New York ◽  
Polymerase Chain Reaction ◽  
West Nile Virus ◽  
New York State ◽  
Polymerase Chain Reaction Detection ◽  
Chain Reaction ◽  
West Nile ◽  
Mosquito Surveillance ◽  
York State ◽  
Polymerase Chain

New York man infected with West Nile virus

The Lancet ◽  
2000 ◽  
Vol 356 (9229) ◽  
pp. 571
Author(s):  
Zoë Mullan
Keyword(s):  
New York ◽  
West Nile Virus ◽  
West Nile
Sign in / Sign up

Export Citation Format

Share Document