scholarly journals Increased Human Herpesvirus 8 Seroprevalence in Young Homosexual Men Who Have Multiple Sex Contacts with Different Partners

1999 ◽  
Vol 179 (1) ◽  
pp. 237-239 ◽  
Author(s):  
David J. Blackbourn ◽  
Dennis Osmond ◽  
Jay A. Levy ◽  
Evelyne T. Lennette
1999 ◽  
Vol 180 (5) ◽  
pp. 1682-1685 ◽  
Author(s):  
Howard D. Strickler ◽  
James J. Goedert ◽  
F. R. Bethke ◽  
C. M. Trubey ◽  
Thomas R. O'Brien ◽  
...  

Sexual Health ◽  
2005 ◽  
Vol 2 (1) ◽  
pp. 13 ◽  
Author(s):  
Andrew E. Grulich ◽  
Philip Cunningham ◽  
Mee-Ling Munier ◽  
Garrett Prestage ◽  
Janaki Amin ◽  
...  

Background: Human herpesvirus 8 (HHV-8) is a common sexually transmitted agent among homosexual men, but there are few Australian data. We aimed to describe the prevalence and risk factors for seropositivity to HHV-8 in Australian homosexual men. Methods: We conducted a prospective cohort study of 179 homosexual men in Sydney Australia in 1992–1998. Detailed data on sexual behaviour was collected annually, and HHV-8 status was determined at the end of the study by an algorithm based on results of an immunofluorescence assay and an enzyme-linked immunoassay to the K8.1 protein of HHV-8. HHV-8 DNA was detected in buffy coats using a nested qualitative PCR. Results: Data on sexual behaviour in at least three interviews and HHV-8 status were available in 174 (97%) of 179 men who agreed to participate. Of these, 31 (18%) were HHV-8 seropositive, and HHV-8 DNA was detected in 5 (16%) of these. The prevalence of HHV-8 infection was much higher in HIV positive (52%) than HIV negative (11%) men (OR 8.60, 95% CI 3.55–20.86). HHV-8 infection was related to more frequent reporting of unprotected receptive anal sex (OR for most frequent versus least frequent category 3.03, 95% CI 1.01–9.03, P trend 0.02), insertive oro–anal sex (OR for most frequent v. least frequent category 3.02, 95% CI 1.15–7.93, P trend 0.02) and receptive oro–anal sex (OR for most frequent v. least frequent category 3.09, 95% CI 1.11–8.60, P trend 0.05) with casual partners. Conclusions: These data are consistent with sexual transmission of HHV-8, but the precise mode of HHV-8 transmission remains unclear. Studies to elucidate the precise mode of sexual transmission of HHV-8 need to focus on potential salivary transmission, and should collect data on the HHV-8 infection and excretion status of the sexual partner.


AIDS ◽  
2001 ◽  
Vol 15 (16) ◽  
pp. 2165-2169 ◽  
Author(s):  
Neil Renwick ◽  
Gerrit Jan Weverling ◽  
Teysir Halaby ◽  
Peter Portegies ◽  
Margreet Bakker ◽  
...  

2017 ◽  
Vol 15 (4) ◽  
Author(s):  
Jiayan Li ◽  
Jinyun Song ◽  
Guolei Tan ◽  
Jianfang Wang ◽  
Zhenxian Zhou ◽  
...  

2003 ◽  
Vol 187 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Robert J. Biggar ◽  
Eric A. Engels ◽  
Denise Whitby ◽  
Dean H. Kedes ◽  
James J. Goedert

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