scholarly journals Isolation and Characterization of Adenovirus 5 from the Brain of an Infant with Fatal Cerebral Edema

2000 ◽  
Vol 31 (3) ◽  
pp. 830-833 ◽  
Author(s):  
Nando K. Chatterjee ◽  
William A. Samsonoff ◽  
N. Balasubramaniam ◽  
Kimberly Rush- Wilson ◽  
William Spargo ◽  
...  
1998 ◽  
Vol 242 (2) ◽  
pp. 436-440 ◽  
Author(s):  
Masaaki Fujimoto ◽  
Ken-ichi Takeshita ◽  
Xiaoyan Wang ◽  
Ikuo Takabatake ◽  
Yuko Fujisawa ◽  
...  

1997 ◽  
Vol 18 (1) ◽  
pp. 87-93
Author(s):  
TAKAHIDE OHISHI ◽  
KAZUAKI IGUCHI ◽  
TOHRU MOCHIZUKI ◽  
MINORU HOSHINO ◽  
YONG-HUA JI ◽  
...  

1994 ◽  
Vol 304 (2) ◽  
pp. 525-530 ◽  
Author(s):  
W J Mawby ◽  
C H Holmes ◽  
D J Anstee ◽  
F A Spring ◽  
M J A Tanner

The CD47 glycoprotein was isolated from human erythrocytes by immunoprecipitation using monoclonal antibody (mAb) BRIC-125. Enzymic deglycosylation of the protein showed it contained N-linked oligosaccharides, and trypsin proteolysis of the protein in situ in the erythrocyte membrane cleaved it into two portions, one of which was glycosylated. Both the intact protein and the glycosylated fragment had blocked N-termini. Amino acid sequence was obtained from several proteolytic fragments of CD47. Comparison with the sequence database showed the protein to be very similar to or identical with OA3, a multispanning membrane protein. The protein also appears to be the same as the integrin-associated protein, which has a role in cell adhesion in non-erythroid cells. CD47 has six potential N-glycosylation sites, five of which are in an Ig superfamily domain. We show that three of these sites carry N-glycans in erythrocytes. Immunocytochemical staining of human tissues showed that CD47 was broadly distributed on mesenchyme and epithelia at multiple sites. Reactivity was particularly prominent in surface and ductular epithelia, and in the brain. The possible roles of the CD47 glycoprotein are discussed.


Peptides ◽  
2011 ◽  
Vol 32 (3) ◽  
pp. 447-453 ◽  
Author(s):  
Hye-Jin Go ◽  
Eun Hee Jo ◽  
Jung-Kil Seo ◽  
Yong-Ki Hong ◽  
Hyung Ho Lee ◽  
...  

2009 ◽  
Vol 364 (1521) ◽  
pp. 1263-1271 ◽  
Author(s):  
Demis Hassabis ◽  
Eleanor A. Maguire

The ability to construct a hypothetical situation in one's imagination prior to it actually occurring may afford greater accuracy in predicting its eventual outcome. The recollection of past experiences is also considered to be a reconstructive process with memories recreated from their component parts. Construction, therefore, plays a critical role in allowing us to plan for the future and remember the past. Conceptually, construction can be broken down into a number of constituent processes although little is known about their neural correlates. Moreover, it has been suggested that some of these processes may be shared by a number of other cognitive functions including spatial navigation and imagination. Recently, novel paradigms have been developed that allow for the isolation and characterization of these underlying processes and their associated neuroanatomy. Here, we selectively review this fast-growing literature and consider some implications for remembering the past and predicting the future.


1997 ◽  
Vol 200 (10) ◽  
pp. 1483-1489 ◽  
Author(s):  
P K Loi ◽  
N Tublitz

The display of complex color patterns of the cuttlefish Sepia officinalis is under the regulation of the FMRFamide-related peptide (FaRP) family, but their exact identities are unknown. We report the isolation and characterization of a full-length FaRP cDNA from the brain of S. officinalis. This cDNA is 1850 base pairs long, including an open reading frame of 996 base pairs. The cDNA encodes a precursor protein containing four FaRPs: ALSGDAFLRF, FIRF, FLRF and FMRF. Each propeptide has a C-terminal glycine residue that is presumably converted post-translationally to an amide. Every FaRP propeptide is also flanked by basic amino acid residues at the amino and carboxy termini, indicative of putative cleavage sites during post-translational processing. Each of the four FaRPs encoded by this cDNA causes chromatophore expansion when assayed in an in vitro chromatophore bioassay. Thus, it is likely that one or more of the FaRPs identified in this study are involved in controlling chromatophore activity in cuttlefish.


2000 ◽  
Vol 31 (2) ◽  
pp. 149-149 ◽  
Author(s):  
T Tozaki ◽  
H Kakoi ◽  
S Mashima ◽  
K Hirota ◽  
T Hasegawa ◽  
...  

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