scholarly journals HEPATIC VITAMIN A IN THE RAT AS AFFECTED BY THE ADMINISTRATION OF DIBENZANTHRACENE

1942 ◽  
Vol 76 (2) ◽  
pp. 143-161 ◽  
Author(s):  
Jules C. Abels ◽  
Alice T. Gorham ◽  
Shirley L. Eberlin ◽  
Robert Halter ◽  
C. P. Rhoads
Keyword(s):  
Vitamin A ◽  
Serum Albumin ◽  
Hepatic Dysfunction ◽  
Glucuronic Acid ◽  
Total Fat ◽  
Hepatic Synthesis ◽  
Esterify Cholesterol

1. The decreased concentrations of vitamin A in the livers of rats given dibenzanthracene probably are due to a particular effect of the carcinogen on the ability of the liver to store the vitamin and not to the production of general hepatic dysfunction. 2. The administration of dibenzanthracene to normal rats does not (a) increase significantly their hepatic content of total fat nor decrease that of phospholipid; (b) impair the ability of their livers to fabricate serum albumin; (c) impair the capacity of their livers to esterify cholesterol or phenol; (d) interfere with the hepatic synthesis and conjugation of glucuronic acid; or (e) interfere with the hepatic storage of riboflavin. 3. The simultaneous ingestion of yeast by the dibenzanthracene-treated rats further depletes their hepatic stores of vitamin A. This depletion conceivably is due to the fact that yeast alone also might deplete the liver of its vitamin A and thus a summation of two similar effects is attained. 4. The results suggest a competition between vitamin A and dibenzanthracene for some substance, possibly a protein, to which vitamin A may be bound in the liver.

scholarly journals Vegetables, Potatoes and Their Products as Sources of Energy and Nutrients to the Average Diet in Poland

2021 ◽  
Vol 18 (6) ◽  
pp. 3217
Author(s):  
Hanna Górska-Warsewicz ◽  
Krystyna Rejman ◽  
Joanna Kaczorowska ◽  
Wacław Laskowski
Keyword(s):  
Cluster Analysis ◽  
Vitamin A ◽  
Vitamin C ◽  
Vitamin B6 ◽  
Dietary Energy ◽  
Sodium Potassium ◽  
Vegetable Products ◽  
Kohonen Neural Networks ◽  
Calcium Phosphorus ◽  
Total Fat

The aim of our study was to analyse vegetables, potatoes and their products as sources of energy and nutrients in the average diet in Poland. Representative data of the 2016 Household Budget Survey from 36,886 households were used. This is the largest study sample in Poland, so we generalized the conclusions to the whole population using the statement ‘average diet’. We analysed three main product groups: vegetables, vegetable products, and potatoes and potatoes products, dividing them into 14 subgroups (e.g., tomatoes, cabbage, carrots, other vegetables, and mushrooms). The percentages of energy, protein, carbohydrates, total fat, nine vitamins (thiamine, riboflavin, niacin, vitamin B6, folate, vitamin C, vitamin A, vitamin D, and vitamin E), seven minerals (calcium, phosphorus, sodium, potassium, iron, magnesium and zinc), and fibre from the analysed food subgroups are presented. Additionally, the influence of household characteristics on the supply of energy and nutrients from each subgroup of vegetables, potatoes, and their products was evaluated using cluster analysis. In the analysis, R programme and Kohonen neural networks were applied. Our study showed that vegetables, potatoes, and their products provide 7.3% of daily dietary energy supply. Vegetables contribute more than 20% of the supply of six nutrients: vitamin C (51.8%), potassium (32.5%), folate (31.0%), vitamin A (30.6%), vitamin B6 (27.8%), and magnesium (20.2%), as well as fibre (31.8%). Cluster analysis distinguished three clusters that differed in nutritional supply from vegetables, potatoes, and their products. Educational level, income measured by quintile groups, village size, socio-economic characteristics, urbanization degree, and land use were the most important factors determining differences between clusters.

Fat-Soluble Vitamins in Human Lactation

2007 ◽  
Vol 77 (5) ◽  
pp. 303-310 ◽  
Author(s):  
Campos ◽  
Paixão ◽  
Ferraz
Keyword(s):  
Vitamin E ◽  
Vitamin A ◽  
Beta Carotene ◽  
Group Differences ◽  
Early Lactation ◽  
Sharp Decline ◽  
Mature Milk ◽  
Human Lactation ◽  
Total Fat ◽  
Fat Soluble Vitamins

Lactation has three distinct phases: colostrum, transition, and mature, with the quantity of fat-soluble vitamins and carotenoids tending to decline while the total fat content increases. The number of deliveries seems to be directly related to higher concentrations of beta-carotene and vitamin E in colostrum. Little is known about vitamin quantities during the other phases. In the present study, vitamin A and E concentrations during different phases of lactation were measured in primiparous and multiparous mothers to analyze the variation and suitability for the diet of a breastfed child. Phase of lactation and number of deliveries were highly significant for log mean vitamin A while only one phase showed significance for log mean vitamin E. There was a sharp decline in the levels of vitamin A and E in the course of the initial phase of lactation. The variability between measurements declined as colostrum transitioned to mature milk. There were significant measurable inter-group differences in retinol levels in milk obtained during early lactation. Vitamin A and E content can reach 2.5 and 1.4 times of levels recommended intake, respectively.

scholarly journals All-trans-retinoyl β-glucuronide: new procedure for chemical synthesis and its metabolism in vitamin A-deficient rats

1996 ◽  
Vol 314 (1) ◽  
pp. 249-252 ◽  
Author(s):  
Bruno BECKER ◽  
Arun B. BARUA ◽  
James A. OLSON
Keyword(s):  
Retinoic Acid ◽  
Vitamin A ◽  
Chemical Synthesis ◽  
Glucuronic Acid ◽  
Major Metabolite ◽  
Triazole Derivative ◽  
Tetrabutylammonium Salt ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
High Yields

All-trans-retinoyl β-glucuronide (RAG) was chemically synthesized in high yields (up to 79%) by a new procedure involving the reaction of the tetrabutylammonium salt of glucuronic acid with all-trans-retinoic acid (RA) via the imidazole or triazole derivative. When RAG was fed orally to vitamin A-deficient rats, RA was identified as the major metabolite in the serum within hours of administration of RAG. Very little or no RAG was detected in the serum. Thus RAG, which was not appreciably hydrolysed to RA in vitamin A-sufficient rats [Barua and Olson (1987) Biochem J. 263, 403–409], was rapidly converted into RA in vitamin A-deficient rats.

Retinoyl Beta-Glucuronic Acid: A Major Metabolite of Vitamin A in Rat Bile

Science ◽  
1965 ◽  
Vol 148 (3666) ◽  
pp. 86-87 ◽  
Author(s):  
P. E. Dunagin ◽  
E. H. Meadows ◽  
J. A. Olson
Keyword(s):  
Vitamin A ◽  
Glucuronic Acid ◽  
Major Metabolite ◽  
Rat Bile

scholarly journals Diet and mortality from common cancers in Brazil: an ecological study

1996 ◽  
Vol 12 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Rosely Sichieri ◽  
James E. Everhart ◽  
Gulnar A. S. Mendonça
Keyword(s):  
Esophageal Cancer ◽  
Vitamin A ◽  
Cancer Mortality ◽  
Mortality Rates ◽  
Ecological Evaluation ◽  
Negatively Associated ◽  
High Fiber ◽  
Total Fat ◽  
Colon Cancer Mortality ◽  
Mate Tea

A prospective ecological evaluation of mortality from common malignancies with dietary risk factors and alcohol consumption was carried out among 10 state capitals of Brazil. Regression analysis was used to examine the association of dietary intake with mortality rates of the most common cancers among adults age 30 years and older. Age-adjusted cancer mortality rates varied 2.4 to 3.3 fold across the state capitals. A positive relationship was observed between energy intake and colon, lung, and esophageal cancer (p<=0.02 for each). Colon cancer mortality was positively associated with consumption of total fat, eggs, alcohol, mate tea, cereals, and vegetables (p<=0.01). Lung cancer was positively associated with mate and cereal intake (p<0.05). Stomach cancer was associated with consumption of eggs (p=0.04); and negatively associated with consumption of high fiber foods, fruits, and vitamin A and C (p<=0.05). Esophageal cancer was positively associated with fat intake, mate and cereals (p<=0.05) and negatively associated with vitamin A (p=0.02); prostate cancer was negatively associated with vitamin C (p=0.007). Breast cancer was not associated with any of the factors studied. The marked variation in cancer mortality rates in Brazil may be partially related to the high variation in dietary components or other diet associated factors.

Vitamin A and Carotenoids in Certain Invertebrates VII. Crustacea: Copepoda

1964 ◽  
Vol 44 (3) ◽  
pp. 685-692 ◽  
Author(s):  
L. R. Fisher ◽  
S. K. Kon ◽  
S. Y. Thompson
Keyword(s):  
Vitamin A ◽  
Lipid Extract ◽  
Calanus Finmarchicus ◽  
High Vitamin ◽  
Generic Groups ◽  
Total Fat ◽  
Pelagic Copepods ◽  
Marine Copepods

SUMMARYTotal fat, carotenoids, and vitamin A were determined physicochemically in sixty-nine species and fifteen generic groups of pelagic marine copepods.Vitamin A was definitely present in Euchirella curticauda and Gaetanus kruppi and possibly so in Gaetanus pileatus and in a sample of Gaetanus spp. No vitamin A activity for vitamin A-depleted rats was found in fractions from a lipid extract of 1854 g of Calanus finmarchicus.The significance of these findings is considered in relation to the high vitamin A reserves in many fish preying upon pelagic copepods.

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