scholarly journals DETERMINATION OF THE QUANTITY OF SECRETING TISSUE IN THE LIVING KIDNEY

1918 ◽  
Vol 28 (3) ◽  
pp. 359-376 ◽  
Author(s):  
C. K. Watanabe ◽  
Jean Oliver ◽  
Thomas Addis
Keyword(s):  
Structure And Function ◽  
Urea Content ◽  
And Function

1. Under the strain induced by the administration of urea, it is possible to demonstrate the relation between the degree of anatomical damage in the kidney and the degree of defect in the urea-excreting capacity induced by uranium. 2. The closest correlation between structure and function was obtained when the ratio between the urea content of the urine and of the blood was used as the measure of function.

Assessment of the impact of nanoparticles on the activity of biomimetic membrane

2021 ◽  
Vol XXXVII (1) ◽  
pp. 89-100
Author(s):  
Dorota Kondej
Keyword(s):  
Occupational Safety ◽  
Biological Membranes ◽  
Structure And Function ◽  
Lipid Monolayer ◽  
Biomimetic Membranes ◽  
Safety And Health ◽  
Biomimetic Membrane ◽  
And Function ◽  
The Impact

This paper presents basic information on a structure and function of biological membranes. Types of biomimetic membranes modelling properties of biological membranes were introduced. The method of testing surface properties of a lipid monolayer, which is the basic type of biomimetic membranes, was described. The presented method makes it possible to evaluate the effect of nanoparticles on the surface activity of biomimetic membranes based on the determination of the surface index MA. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.

scholarly journals 60 YEARS OF POMC: Lipotropin and beta-endorphin: a perspective

2016 ◽  
Vol 56 (4) ◽  
pp. T13-T25 ◽  
Author(s):  
D G Smyth
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Analysis ◽  
Structure And Function ◽  
Biologically Active ◽  
Molecular Endocrinology ◽  
And Function ◽  
The Brain ◽  
Quantitative Amino Acid Analysis

Many important fields of research had a humble origin. In the distant past, A J P Martin’s discovery that amino acids could be separated by paper chromatography and Moore and Stein’s use of columns for quantitative amino acid analysis provided the first steps towards the determination of structure in complex biologically active molecules. They opened the door to reveal the essential relationship that exists between structure and function. In molecular endocrinology, for example, striking advances have been made by chemists with their expertise in the identification of structure working with biologists who contributed valuable knowledge and experience. Advantage was gained from the convergence of different background, and it is notable that the whole is greater than the sum. In the determination of structure, it may be recalled that four of the world’s great pioneers (Archibald Martin, Rodney Porter, Fred Sanger and Vincent du Vigneaud) were acknowledged for their fundamental contributions when individually they were awarded the Nobel Prize. They foresaw that the identification of structure would prove of outstanding importance in the future. Indeed, study of the structures of β-endorphin and enkephalin and the different forms of opiate activity they engender has led to a transformation in our understanding of chemical transmission in the brain.

scholarly journals Structural insights into the architecture and assembly of eukaryotic flagella

2020 ◽  
Vol 7 (11) ◽  
pp. 289-299
Author(s):  
Narcis-Adrian Petriman ◽  
Esben Lorentzen
Keyword(s):  
Structure And Function ◽  
Eukaryotic Cells ◽  
Repetitive Nature ◽  
Unicellular Organisms ◽  
Cilia And Flagella ◽  
And Function ◽  
Signaling Components ◽  
Structural Insights ◽  
Insight Into

Cilia and flagella are slender projections found on most eukaryotic cells including unicellular organisms such as Chlamydomonas, Trypanosoma and Tetrahymena, where they serve motility and signaling functions. The cilium is a large molecular machine consisting of hundreds of different proteins that are trafficked into the organelle to organize a repetitive microtubule-based axoneme. Several recent studies took advantage of improved cryo-EM methodology to unravel the high-resolution structures of ciliary complexes. These include the recently reported purification and structure determination of axonemal doublet microtubules from the green algae Chlamydomonas reinhardtii, which allows for the modeling of more than 30 associated protein factors to provide deep molecular insight into the architecture and repetitive nature of doublet microtubules. In addition, we will review several recent contributions that dissect the structure and function of ciliary trafficking complexes that ferry structural and signaling components between the cell body and the cilium organelle.

Structure and function encoding of a bidirectional activatable synergetic DNA machine for speeded and ultrasensitive determination of microRNAs

Talanta ◽  
2021 ◽  
pp. 123037
Author(s):  
Lan Lin ◽  
Yingying Zhang ◽  
Qiongying Wei ◽  
Hongguang Lin ◽  
Xiaoping Li ◽  
...  
Keyword(s):  
Structure And Function ◽  
Dna Machine ◽  
And Function

Sex Differences in Cognition: The New Rise of Biologism

1993 ◽  
Vol 10 (1) ◽  
pp. 2-5
Author(s):  
Lesley J. Rogers
Keyword(s):  
Sex Differences ◽  
Brain Structure ◽  
Structure And Function ◽  
Representation Of Women ◽  
Brain Structure And Function ◽  
Environmental Stimulation ◽  
And Function ◽  
The Brain

AbstractCurrently there is an increase in the number of articles published in scientific journals and in the popular scientific media that claim a biological basis for sex differences in cognition and in certain structures in the brain. It can be argued that there is over-emphasis on the differences rather than similarities between the sexes, but it is even more important to question the assumed causation of the differences. This paper discusses recent evidence for an interactive role of early experience and hormonal condition in determining sex differences in brain structure and function. Although early studies using rats were thought to show that the male sex hormone, testosterone, acts on the brain in early life to direct its differentiation into either the male or female form, it is know known that this result comes about indirectly by changing the mother’s behaviour towards the pups. The hormone does not act on the brain directly but rather it alters the environment in which the young animals are rasied and this, in turn, influences the development of the brain. Indeed, the brain is in dynamic register with its environment both during development and in adulthood. Other examples also show that old ideas of rigid biological determination of brain structure and function need to be laid aside.The hypotheses for hormonal causation of sex differences humans rely heavily, if not exclusively, on the earlier interpretation of the experiments with rats, and there seems to be resistance to changing these notions based on the new discoveries. Apparently, there is strong pressure to cling on to biological determinist theories for sex differences in behaviour, and this has profound effects on social and educational policy. For example, biological determinism has been used to justify under representation of women in certain professions. Realisation of the dramatic effects that environmental stimulation and learning can have on the development of brain and behaviour leads us to an optimistic position for social change towards equality for women.

scholarly journals Determination of Right Ventricular Structure and Function in Normoxic and Hypoxic Mice

Circulation ◽  
1998 ◽  
Vol 98 (10) ◽  
pp. 1015-1021 ◽  
Author(s):  
Marielle Scherrer-Crosbie ◽  
Wolfgang Steudel ◽  
Patrick R. Hunziker ◽  
Gary P. Foster ◽  
Leoncio Garrido ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Structure And Function ◽  
Ventricular Structure ◽  
And Function
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