An Exploratory Study of Resistance Training and Functional Ability in Older Adults

2009 ◽  
Vol 33 (3) ◽  
pp. 179-190 ◽  
Author(s):  
Gayle Appel Doll
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Functional Ability ◽  
Exploratory Study

Effect of Progressive Resistance Training on Circulating Adipogenesis-, Myogenesis-, and Inflammation-Related microRNAs in Healthy Older Adults: An Exploratory Study

Gerontology ◽  
2020 ◽  
Vol 66 (6) ◽  
pp. 562-570
Author(s):  
Hung-Wen Liu ◽  
Hao-Chien Cheng ◽  
Shun-Hsi Tsai ◽  
Wen-Hsien Sun
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Exploratory Study ◽  
Fold Change ◽  
Protective Effects ◽  
Circulating Mirnas ◽  
Necrosis Factor Alpha ◽  
Healthy Older Adults ◽  
Walking Capacity ◽  
Physiological Adaptations

<b><i>Background:</i></b> Functional and physiological adaptations induced by resistance training have been extensively studied in older adults. However, microRNA (miRNA) as the novel regulator in protective effects remains poorly understood. <b><i>Objective:</i></b> The purpose of an exploratory study was to analyze the response of a panel of circulating miRNAs to adaptations mediated by resistance training. <b><i>Methods:</i></b> Ten healthy older adults (age: 67.6 ± 2.2 years, 7 women and 3 men) without previous experience in resistance training were recruited. Blood samples were collected at baseline and after a 12-week resistance training. Next-generation sequencing was used to determine circulating miRNA responses to chronic resistance training. <b><i>Results:</i></b> After the 12-week training, physical functions including grip strength, lower body strength and endurance, and walking capacity were improved in the older adults, while the serum levels of leptin (from 18.1 ± 20.0 to 14.9 ± 17.6 ng/mL, <i>p</i> = 0.029) and tumor necrosis factor alpha (TNFα; from 4.4 ± 0.6 to 4.0 ± 0.6 pg/mL, <i>p</i> &#x3c; 0.001) were significantly decreased. In addition, adipogenesis-related miRNAs (miR-103a-3p, -103b, -143-5p, -146b-3p, -146b-5p, -17-5p, -181a-2-3p, -181b-5p, -199a-5p, -204-3p, and -378c), anti-adipogenesis-related miRNAs (miR-155-3p, -448, and -363-3p), myogenesis-related miRNAs (miR-125b-1-3p, -128-3p, -133a-3p, 155-3p, -181a-2-3p, -181b-5p, -199a-5p, -223-3p, and -499a-5p), and inflammation-related miRNAs (miR-146b-3p, -146b-5p, -155-3p, -181a-2-3p, and -181b-5p) were changed significantly in the older adults after training (fold change &#x3e;2, <i>p</i> &#x3c; 0.05). The log<sub>2</sub> fold change of miRNA-125-1-3p was inversely correlated with delta walking time (<i>R</i> = –0.685, <i>p</i> = 0.029) and change in insulin-like growth factor 1 (<i>R</i> = –0.644, <i>p</i> = 0.044). <b><i>Conclusions:</i></b> Our results can help explain the link between specific circulating miRNAs and beneficial effects of resistance training on functional and physiological adaptations in older adults.

Staying Strong Together: Older People Engaging in Resistance Training With a Peer

2020 ◽  
pp. 1-7
Author(s):  
Paige Watkins ◽  
Anne-Marie Hill ◽  
Ian K. Thaver ◽  
Elissa Burton
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Older People ◽  
Training Program ◽  
Peer Support ◽  
Exploratory Study ◽  
Resistance Training Program ◽  
Retirement Village ◽  
Semistructured Interviews

The aim of this qualitative exploratory study was to investigate older adults’ perceptions of having a peer to encourage their participation in resistance training. The participants were recruited from a retirement village to undergo a 6-week resistance training program. Some participants attended a center; others participated in their home. Data were collected via semistructured interviews and analyzed thematically using a six-phase framework to obtain the participants’ perspectives about the peer support they received. The participants (n = 21) had divergent views about peer support, with some finding it enabling, while others did not find it helpful. Overall, the participants suggested that peer support could be beneficial if offered as a choice. Further research is needed to determine whether peer support assists in sustaining resistance training engagement among older adults when the aspect of choice is included.

Effects of a resistance training community programme in older adults

2021 ◽  
pp. 1-16
Author(s):  
Majid Mufaqam Syed-Abdul ◽  
Chrissa L. McClellan ◽  
Elizabeth J. Parks ◽  
Stephen D. Ball
Keyword(s):  
Older Adults ◽  
Body Mass Index ◽  
Resistance Training ◽  
Muscle Mass ◽  
Body Mass ◽  
Fat Mass ◽  
Training Programme ◽  
Haemoglobin A1c ◽  
Community Based ◽  
Resistance Training Programme

Abstract Ageing is associated with reduced muscle mass, strength, flexibility and balance, resulting in a poor quality of life (QOL). Past studies have occurred in highly controlled laboratory settings which provide strong support to determine whether similar gains can be made in community programmes. Twenty participants were enrolled in an eight-week community-based resistance training programme (mean age = 61.3 (standard error (SE) = 0.9) years); Body Mass Index = 32.0 (SE = 1.3) kg/m2). All participants completed surveys to assess outcomes associated with QOL. Given the relationship between muscle function and nerve health, nerve conduction studies (NCS) were also conducted in a separate group of participants (mean age = 64.9 (SE = 2.0) years; Body Mass Index = 32.6 (SE = 1.9) kg/m2). This community-based training programme significantly improved QOL measures in older adults (p < 0.001). Although weight loss was not the primary outcome of the study, participants reduced their body weights (p < 0.001), by primarily reducing fat mass (p = 0.007) while maintaining muscle mass. Significant improvements were observed in muscle strength (2.2%), flexibility and balance (3.2–464.2%, p ⩽ 0.05 for all). Improvements were also observed in plasma glucose (p = 0.05), haemoglobin A1C (p = 0.06) and aldolase enzyme levels (p < 0.001). Scores for surveys on memory and sleep improved (p < 0.05). Improved QOL was associated with increased lean mass (r = −0.714, p = 0.002), decreased fat mass (r = −0.702, p = 0.003) and improved flexibility and balance (r = −0.627, p = 0.008). An eight-week, community-based resistance training programme significantly improved QOL in older adults. Influence on the lipid profile and NCS still needs further investigation.

scholarly journals Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin

GeroScience ◽  
2021 ◽  
Author(s):  
Douglas E. Long ◽  
Bailey D. Peck ◽  
Steven C. Tuggle ◽  
Alejandro G. Villasante Tezanos ◽  
Samuel T. Windham ◽  
...  
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Physical Function ◽  
Lipid Content ◽  
Muscle Lipid ◽  
Training Outcomes

scholarly journals Prevalence and risk factors of delirium and subsyndromal delirium in older adults

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Maha Hosam El-Din Ibrahim ◽  
Manal Elmasry ◽  
Fady Nagy ◽  
Ahmed Abdelghani
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Functional Ability ◽  
Cognitive Assessment ◽  
Length Of Hospital Stay ◽  
Assessment Method ◽  
Assessment Tools ◽  
Subsyndromal Delirium ◽  
Confusion Assessment ◽  
Definition Of

Abstract Background Delirium is a common geriatric problem associated with poor outcomes. Subsyndromal delirium (SSD) is characterized by the presence of certain symptoms of delirium yet, not satisfying the definition of full-blown delirium, defined by categorical elements, and is usually referred to as the presence of one or more symptoms in the confusion assessment method (CAM). This study aimed to investigate the prevalence and risk factors of delirium and SSD in older adults admitted to the hospital. Five hundred eighty-eight elderly (above 65 years) Egyptian patients were recruited from January 2019 to February 2020. After explaining the purpose of the study and assuring the confidentiality of all participants, an informed consent was obtained from the participant or a responsible care giver for those who were not able to give consent. All patients were subjected ‘on admission’ to thorough history taking, clinical examination, and comprehensive geriatric assessment including confusion assessment tools, mini-mental state examination, and functional assessment using Barthel index score. Results The current study showed that 19.6% of patients had delirium and 14.1% of patients had SSD with combined prevalence of 33.7%. Most common causes included metabolic, infection, organic brain syndrome, and dehydration. The current study reported significant proportionate relation between cognitive assessment and functional ability, so patients with a score of 23 MMSE had good functional ability, while cognitive assessment using mini-mental score shows inversed relation to delirium and SSD using CAM score. Conclusion Delirium is independently associated with adverse short-term and long-term outcomes, including an increase in mortality, length of hospital stay, discharge to an institution, and functional decline on discharge. Subsyndromal delirium (SSD) is characterized by the presence of certain symptoms of delirium, not yet satisfying the definition of full-blown delirium but it can identify patients with early cognitive and functional disabilities, and because of high prevalence of delirium and SSD. Efforts to prevent or early detection may identify patients who warrant clinical attention.

Fall-related cognition, motor function, functional ability, and depression measures in older adults with dementia

2020 ◽  
Vol 47 (4) ◽  
pp. 487-494
Author(s):  
Hyun-Ju Park ◽  
Nam-Gi Lee ◽  
Tae-Woo Kang
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Motor Function ◽  
Functional Ability ◽  
Fall Risk ◽  
Geriatric Depression Scale ◽  
Depression Scale ◽  
Korean Version ◽  
Risk Of Fall ◽  
Clinical Measurements

BACKGROUND: As the severity of dementia progresses over time, cognition and motor functions such as muscle strength, balance, and gait are disturbed, and they eventually increase the risk of fall in patients with dementia. OBJECTIVE: To determine the relationship between the fall risk and cognition, motor function, functional ability, and depression in older adults with dementia. METHODS: Seventy-four older adults diagnosed with dementia were recruited. Clinical measurements included the Fall Risk Scale by Huh (FSH), Korean version of the Mini-Mental State Examination (MMSE-K), hand grip strength (HGS), Tinetti Performance Oriented Mobility Assessment (POMA), 10-m walk test (10-MWT), Korean version of the Modified Barthel Index (MBI-K), and the Geriatric Depression Scale (GDS). RESUTLS: The MMSE-K was significantly correlated with the FSH, HGS, and the MBI-K, and FSH was significantly correlated with all of the other outcome measures. In particular, the MMSE-K, HGS, POMA, and the MBI-K were negatively correlated with fall history among the FHS sub-items. Additionally, the MMSE sub-item, attention/concentration was associated with the FSH, HGS, POMA, and the MBI-K. CONCLUSIONS: These findings suggest that falling is significantly related to impaired cognition, reduced muscle strength, impaired balance, gait, and activities of daily living abilities, and depression in older adults with dementia.

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