scholarly journals Postprandial lipid metabolism: effects of dietary fatty acids

1997 ◽  
Vol 56 (2) ◽  
pp. 679-692 ◽  
Author(s):  
Christine M. Williams
Keyword(s):  
Fatty Acids ◽  
Lipid Metabolism ◽  
Dietary Fatty Acids ◽  
Postprandial Lipid Metabolism ◽  
Postprandial Lipid

scholarly journals The effect of test meal monounsaturated fatty acid: saturated fatty acid ratio on postprandial lipid metabolism

1998 ◽  
Vol 79 (5) ◽  
pp. 419-424 ◽  
Author(s):  
Helen M. Roche ◽  
Antonis Zampelas ◽  
Kim G. Jackson ◽  
Christine M. Williams ◽  
Michael J. Gibney
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Lipid Metabolism ◽  
Test Meal ◽  
Saturated Fatty Acids ◽  
Hdl Cholesterol ◽  
Minor Effect ◽  
Postprandial Lipid Metabolism ◽  
Significant Difference ◽  
Postprandial Lipid

Epidemiological evidence shows that a diet high in monounsaturated fatty acids (MUFA) but low in saturated fatty acids (SFA) is associated with reduced risk of CHD. The hypocholesterolaemic effect of MUFA is known but there has been little research on the effect of test meal MUFA and SFA composition on postprandial lipid metabolism. The present study investigated the effect of meals containing different proportions of MUFA and SFA on postprandial triacylglycerol and non-esterified fatty acid (NEFA) metabolism. Thirty healthy male volunteers consumed three meals containing equal amounts of fat (40g), but different proportions of MUFA (12, 17 and 24% energy) in random order. Postprandial plasma triacylglycerol, apolipoprotein B-48, cholesterol, HDL-cholesterol, glucose and insulin concentrations and lipoprotein lipase (EC 3.1.1.34) activity were not significantly different following the three meals which varied in their levels of SFA and MUFA. There was a significant difference in the postprandial NEFA response between meals. The incremental area under the curve of postprandial plasma NEFA concentrations was significantly (P = 0·03) lower following the high-MUFA meal. Regression analysis showed that the non-significant difference in fasting NEFA concentrations was the most important factor determining difference between meals, and that the test meal MUFA content had only a minor effect. In conclusion, varying the levels of MUFA and SFA in test meals has little or no effect on postprandial lipid metabolism.

Impact of Rapeseed and Soy Lecithin on Postprandial Lipid Metabolism, Bile Acid Profile and Gut Bacteria in Mice

2021 ◽  
pp. 2001068
Author(s):  
Chloé Robert ◽  
Charline Buisson ◽  
Fabienne Laugerette ◽  
Hélène Abrous ◽  
Dominique Rainteau ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Bile Acid ◽  
Gut Bacteria ◽  
Soy Lecithin ◽  
Postprandial Lipid Metabolism ◽  
Postprandial Lipid

Dietary fatty acids early in life affect lipid metabolism and adiposity in young rats

Lipids ◽  
2006 ◽  
Vol 41 (6) ◽  
pp. 535-541 ◽  
Author(s):  
Ana Paula S. Silva ◽  
Daniella E. D. Guimarães ◽  
Daniella M. Mizurini ◽  
Ingrid C. Maia ◽  
Susana Ortiz-Costa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lipid Metabolism ◽  
Dietary Fatty Acids ◽  
Young Rats

Abstract: 549 NEW ASPECTS OF POSTPRANDIAL LIPID METABOLISM

2009 ◽  
Vol 10 (2) ◽  
pp. e1618
Author(s):  
U Beisiegel ◽  
J Heeren ◽  
A Laatsch
Keyword(s):  
Lipid Metabolism ◽  
Postprandial Lipid Metabolism ◽  
Postprandial Lipid

scholarly journals Rapeseed Lecithin Increases Lymphatic Lipid Output and α-Linolenic Acid Bioavailability in Rats

2020 ◽  
Vol 150 (11) ◽  
pp. 2900-2911
Author(s):  
Chloé Robert ◽  
Leslie Couëdelo ◽  
Carole Knibbe ◽  
Laurence Fonseca ◽  
Charline Buisson ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Linolenic Acid ◽  
Soybean Lecithin ◽  
Microsomal Triglyceride Transfer Protein ◽  
Metabolic Effects ◽  
Control Group ◽  
Postprandial Lipid Metabolism ◽  
Postprandial Lipid ◽  
The Impact ◽  
Rapeseed Lecithin

ABSTRACT Background Soybean lecithin, a plant-based emulsifier widely used in food, is capable of modulating postprandial lipid metabolism. With arising concerns of sustainability, alternative sources of vegetal lecithin are urgently needed, and their metabolic effects must be characterized. Objectives We evaluated the impact of increasing doses of rapeseed lecithin (RL), rich in essential α-linolenic acid (ALA), on postprandial lipid metabolism and ALA bioavailability in lymph-cannulated rats. Methods Male Wistar rats (8 weeks old) undergoing a mesenteric lymph duct cannulation were intragastrically administered 1 g of an oil mixture containing 4% ALA and 0, 1, 3, 10, or 30% RL (5 groups). Lymph fractions were collected for 6 h. Lymph lipids and chylomicrons (CMs) were characterized. The expression of genes implicated in intestinal lipid metabolism was determined in the duodenum at 6 h. Data was analyzed using either sigmoidal or linear mixed-effects models, or one-way ANOVA, where appropriate. Results RL dose-dependently increased the lymphatic recovery (AUC) of total lipids (1100 μg/mL·h per additional RL%; P = 0.010) and ALA (50 μg/mL·h per additional RL%; P = 0.0076). RL induced a faster appearance of ALA in lymph, as evidenced by the exponential decrease of the rate of appearance of ALA with RL (R2 = 0.26; P = 0.0064). Although the number of CMs was unaffected by RL, CM diameter was increased in the 30%-RL group, compared to the control group (0% RL), by 86% at 3–4 h (P = 0.065) and by 81% at 4–6 h (P = 0.0002) following administration. This increase was positively correlated with the duodenal mRNA expression of microsomal triglyceride transfer protein (Mttp; ρ= 0.63; P = 0.0052). The expression of Mttp and secretion-associated, ras-related GTPase 1 gene homolog B (Sar1b, CM secretion), carnitine palmitoyltransferase IA (Cpt1a) and acyl-coenzyme A oxidase 1 (Acox1, beta-oxidation), and fatty acid desaturase 2 (Fads2, bioconversion of ALA into long-chain n–3 PUFAs) were, respectively, 49%, 29%, 74%, 48%, and 55% higher in the 30%-RL group vs. the control group (P < 0.05). Conclusions In rats, RL enhanced lymphatic lipid output, as well as the rate of appearance of ALA, which may promote its subsequent bioavailability and metabolic fate.

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