First report of Elaphostrongylus cervi in Spanish red deer Cervus elaphus hispanicus

2002 ◽  
Vol 76 (1) ◽  
pp. 91-93 ◽  
Author(s):  
F. F. Valcárcel ◽  
C. García Romero

AbstractElaphostrongylus cervi Cameron, 1931 was identified in six Cervus elaphus hispanicus sampled in Cuenca, central Spain. A total of 23 adult worms were found in the central nervous system with a mean of 3.8. Although E. cervi is reported to be widespread in cervids, this is the first time it has been recorded in Spanish red deer.

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
İsmail Gülşen ◽  
Hakan Ak ◽  
Tevfik Yilmaz ◽  
Mehmet Deniz Bulut ◽  
İsmet Alkış ◽  
...  

Gliosarcoma is a rare tumor of the central nervous system and it constitutes about 1 to 8% of all malignant gliomas. In this report we are presenting a recurrent gliosarcoma case during a pregnancy in a 30-year-old woman. This is the first report presenting gliosarcoma in the pregnancy.


1966 ◽  
Vol 44 (5) ◽  
pp. 815-820 ◽  
Author(s):  
R. V. Anderson

Fifteen ganglia, associated with the nerve ring are reported. With the exception of the paired lateral cephalic papillary, postlateral papillary, and the amphidial ganglia, nine ganglia are linked by laterolateral commissures which are described for the first time. The laterolateral commissures appear to originate from paired internolateral ganglia located above and below the nerve ring. The longitudinal dorsal and paired ventral, amphidial, and lateral cephalic papillary nerves are traced from origin at their respective ganglia of the central nervous system to their termination. The paired ventral nerves pass to the right and left of the vagina, remaining double throughout most of their length. Portions of the rectosympathetic nervous systems are described in males and females. In the description of the new species based on males and females, the structure of the amphid is clarified, and the position of the plicated guiding ring and the dorsoventral width of the plicated guiding ring, expressed as percentage of spear length, are used as diagnostic characters. Illustrations and photomicrographs are provided.


2020 ◽  
Vol 18 (4) ◽  
pp. 256-265
Author(s):  
L. N. Prakhova ◽  
A. S. Parfyonova ◽  
Zh. I. Savintseva ◽  
A. G. Ilves ◽  
E. V. Bubnova ◽  
...  

CLIPPERS (Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is a rare inflammatory disease of the central nervous system, during which the pons of the brain is damaged. This disease was described for the first time in 2010 by S.J. Pittock et.al. At present, there have been around 50 described cases of the disease. Up to the present moment, there are difficulties diagnosing this disease. In the article, a literature review and three clinical cases are presented. Furthermore, the necessity of further research is shown for improving the accuracy and specificity of the diagnostic criteria, as well as for defining biomarkers and developing algorithms of effective therapy.


2021 ◽  
Vol 12 (1) ◽  
pp. 24-29
Author(s):  
Zh. I. Savintseva ◽  
A. G. Ilves ◽  
V. M. Lebedev ◽  
O. M. Novoselova ◽  
L. N. Prakhova

Retino-cochleo-cerebral angiopathy or Susac syndrome is a rare autoimmune disease that selectively affects the vessels of the retina, the inner ear and the central nervous system. Differentiation of Susac syndrome and multiple sclerosis presents difficulties due to the similarity of MRI semiotics of these two diseases. This article presents two clinical cases of patients with Susac syndrome who were diagnosed with multiple sclerosis at the onset of the disease. Based on the analysis of our own clinical observations and literature data, the issues of differential diagnosis of Susac syndrome and multiple sclerosis are highlighted. For the first time a variant of the MRI picture transformation in Susac syndrome is presented.


2019 ◽  
Vol 1 (Supplement_2) ◽  
pp. ii2-ii2
Author(s):  
Webster K Cavenee

Abstract The most recent version of the WHO Classification of Tumours of the Central Nervous System includes, for the first time, the joint consideration of tumor pathology with tumor genetics as measured in various ways. This has come decades after the first recognition of genetic lesions in tumor genomes as discerned by cytogenetics and more than 30 years after the first reports of specific and recurrent genetic abnormalities in human tumors, particularly gliomas. This information is vitally important because it is now being used not just for tumor diagnosis but also to indicate specific therapies. In this lecture, I will review the increasingly precise methodologies being employed, the resultant genetic lesions being uncovered and the increasing import of such information for therapeutic selection.


2020 ◽  
Vol 21 (15) ◽  
pp. 1095-1100
Author(s):  
Alessandro Serretti ◽  
Chiara Fabbri

Over 20 years after the initial report of gene variants within the central nervous system modulating antidepressant response, we are now facing for the first time routine clinical pharmacogenetic applications. The scientific community is divided between enthusiasm and skepticism. It seems clear that the benefit of existing tools is not huge, at least for the central nervous system gene variants, while it is generally accepted for the metabolic gene variants. Findings from large international consortia suggest for the first time in psychiatric genetic research history that cumulative scores comprising many variants across the whole genome may reliably constitute liability factors for psychiatric disorders, this approach will most likely improve also present pharmacogenetic tools. A composite genetic score complemented with clinical risk factors for each patient is the most promising approach for a more effective method of targeted treatment for patients with depression.


2016 ◽  
Vol 14 (3) ◽  
Author(s):  
Thiago N. A. Pereira ◽  
Ricardo M. C. Castro

ABSTRACT The brain of Brycon orbignyanus is described as a model for future studies of the gross morphology of the central nervous system in Characiformes. The study of brain gross morphology of 48 distinct taxa of Characiformes, one of Cypriniformes, two of Siluriformes and two of Gymnotiformes, allowed us to propose, for the first time, six putative brain synapomorphies for the Characiformes and also two possibly unique gross brain morphology characters for the Siluriformes. A detailed protocol for the extraction of the brain in Characiformes is also provided.


1938 ◽  
Vol 68 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Albert B. Sabin ◽  
Peter K. Olitsky

With a method of intranasal instillation of poliomyelitis virus that brings about infection of all M. rhesus monkeys subjected to it, a study was undertaken of the fate of nasally instilled virus in normal and convalescent, immune animals. Control experiments revealed that nasal mucosa of normal monkeys contained no observable antiviral factors and that when five or ten minimal cerebral infective doses were added to the mucosa, virus could be detected by the employed procedure. In the olfactory bulbs even a single infective dose could be recovered, since suspensions of both bulbs could be transferred to the brain of a monkey without any loss of material. After nasal instillation of virus in normal monkeys, it disappeared quickly (4 hours or less) and could be recovered neither from the excised nasal mucosa nor from the olfactory bulbs during the first 48 hours. At 72 hours, just before or coincident with the first rise of temperature, virus was found in very small amounts in the nasal mucosa and for the first time also in the olfactory bulbs. At 96 hours, at least 3 days before the appearance of nervous signs, and later, while virus continued to be present in considerable amounts in the olfactory bulbs (and presumably elsewhere in the central nervous system), none was detected in the nasal mucosa. In convalescent, immune animals receiving the same strain of virus intranasally which caused the original infection, none could be recovered from the nasal mucosa or central nervous system at 4 hours, 1, 2, 3, 4, 5, and 7 days. The bearing of these observations on the problem of host to host transmission of poliomyelitis virus is discussed.


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