scholarly journals Recurrent Gliosarcoma in Pregnancy

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
İsmail Gülşen ◽  
Hakan Ak ◽  
Tevfik Yilmaz ◽  
Mehmet Deniz Bulut ◽  
İsmet Alkış ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Malignant Gliomas ◽  
Rare Tumor ◽  
First Report ◽  
The Central Nervous System ◽  
In Pregnancy

Gliosarcoma is a rare tumor of the central nervous system and it constitutes about 1 to 8% of all malignant gliomas. In this report we are presenting a recurrent gliosarcoma case during a pregnancy in a 30-year-old woman. This is the first report presenting gliosarcoma in the pregnancy.

Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review

Neurosurgery ◽  
2015 ◽  
Vol 78 (3) ◽  
pp. 343-352 ◽  
Author(s):  
Arnault Tauziede-Espariat ◽  
Andre Maues de Paula ◽  
Melanie Pages ◽  
Annie Laquerriere ◽  
Emilie Caietta ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Overall Survival ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Clinical Symptoms ◽  
Malignant Gliomas ◽  
Leptomeningeal Gliomatosis ◽  
Molecular Features ◽  
The Central Nervous System ◽  
The Mean

Abstract BACKGROUND: Primary leptomeningeal gliomatosis (PLG) is a poorly recognized tumor of the central nervous system. OBJECTIVE: To describe the histopathological, immunohistochemical, and molecular features of PLG. METHODS: Results of our multicentric retrospective study of 6 PLG cases (3 pediatric and 3 adult) were compared with literature data. RESULTS: The mean age was 54.7 years for adults and 8.7 years for children, with 3 males and 3 females. Clinical symptoms were nonspecific. Cerebrospinal fluid analyses showed a high protein level often associated with pleocytosis but without neoplastic cells. On neuroimaging, diffuse leptomeningeal enhancement and hydrocephalus were observed, except in 1 case. PLG was mostly misinterpreted as infectious or tumoral meningitis. The first biopsy was negative in 50% of cases. Histopathologically, PLG cases corresponded to 1 oligodendroglioma without 1p19q codeletion and 5 astrocytomas without expression of p53. No immunostaining for IDH1R132H and no mutations of IDH1/2 and H3F3A genes were found. Overall survival was highly variable (2-82 months) but seems to be increased in children treated with chemotherapy. CONCLUSION: This study shows the difficulties of PLG diagnosis. The challenge is to achieve an early biopsy to establish a diagnosis and to begin a treatment, but the prognosis remains poor. PLG seems to have a different molecular and immunohistochemical pattern compared with intraparenchymal malignant gliomas.

Idiopathic Granulomatous Angiitis of the Central Nervous System in Pregnancy

1997 ◽  
Vol 6 (1) ◽  
pp. 58-60
Author(s):  
Marcelo J. Barrionuevo ◽  
Richard A. Bronsteen ◽  
Lawrence M. Eilender ◽  
Debra J. Wright ◽  
Gregory L. Goyert
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Granulomatous Angiitis ◽  
The Central Nervous System ◽  
In Pregnancy

The distribution of bromine content of dibromodulcitol in the central nervous system of patients with malignant gliomas

1990 ◽  
Vol 26 (2) ◽  
pp. 79-82 ◽  
Author(s):  
Ibolya L. Sziklai ◽  
Dénes Áfra ◽  
Maria Ordogh ◽  
László Institoris ◽  
Sandor Kerpel-Fronius ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Malignant Gliomas ◽  
Bromine Content ◽  
The Central Nervous System

Congenital Glioblastoma Multiforme: An Unusual and Challenging Tumor

2017 ◽  
Vol 48 (06) ◽  
pp. 403-412 ◽  
Author(s):  
Dimitrios Anestis ◽  
Christina Ble ◽  
Vassilios Tsitouras ◽  
Christos Tsonidis ◽  
Parmenion Tsitsopoulos
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Glioblastoma Multiforme ◽  
Natural History ◽  
Surgical Resection ◽  
Treatment Strategies ◽  
Molecular Profile ◽  
Rare Tumor ◽  
Mortality And Morbidity ◽  
The Central Nervous System

AbstractCongenital glioblastoma multiforme is a rare tumor of the central nervous system with unique features. The existing evidence on its pathogenesis, genetic and molecular profile, special characteristics, treatment, and prognosis is reviewed. An increased number of antenatal diagnoses and prolonged survival for those individuals who can tolerate combined surgical resection and chemotherapy has been noted. The overall prognosis, however, remains poor. A better understanding of this unusual entity is important. Further research is needed to discern tumor's pathogenesis and natural history. This will likely lead to the development and implementation of treatment strategies that may decrease mortality and morbidity in these patients.

Dissemination of malignant gliomas beyond the central nervous system

2006 ◽  
Vol 11 (2) ◽  
pp. 101-104
Author(s):  
Maria L. Pamucka ◽  
Lidia Czopkiewicz ◽  
Ewa Skrzypczyńska ◽  
Piotr Tokar
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Malignant Gliomas ◽  
The Central Nervous System

scholarly journals Current and Future Gene Therapy for Malignant Gliomas

2003 ◽  
Vol 2003 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Takao Kanzawa ◽  
Hideaki Ito ◽  
Yasuko Kondo ◽  
Seiji Kondo
Keyword(s):  
Gene Therapy ◽  
Central Nervous System ◽  
Clinical Trials ◽  
Nervous System ◽  
Malignant Gliomas ◽  
Therapeutic Approaches ◽  
Average Life ◽  
Average Life Expectancy ◽  
Experimental Animal Models ◽  
The Central Nervous System

Malignant gliomas are the most common neoplasm in the central nervous system. When treated with conventional treatments including surgery, irradiation, and chemotherapy, the average life expectancy of the most malignant type, glioblastoma multiforme is usually less than 1 year. Therefore, gene therapy is expected to be an effective and possibly curative treatment. Many gene therapeutic approaches have demonstrated efficacy in experimental animal models. However, the current clinical trials are disappointing. This review focuses on current therapeutic genes/vectors/delivery systems/targeting strategies in order to introduce updated trends and hopefully indicate prospective gene therapy for malignant gliomas.

Idiopathic granulomatous angiitis of the central nervous system in pregnancy: The first case report

1997 ◽  
Vol 6 (1) ◽  
pp. 58-60 ◽  
Author(s):  
Marcelo J. Barrionuevo ◽  
Richard A. Bronsteen ◽  
Lawrence M. Eilender ◽  
Debra J. Wright ◽  
Gregory L. Goyert
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Granulomatous Angiitis ◽  
First Case ◽  
The Central Nervous System ◽  
In Pregnancy

scholarly journals FEATURES OF MEMORY IN CHILDREN OF PRESCHOOL AGE WITH CONSEQUENCES OF PERINATAL LESIONS OF THE CENTRAL NERVOUS SYSTEM

2014 ◽  
Vol 13 (1) ◽  
pp. 161-165
Author(s):  
T. S. Krivonogova ◽  
Ye. V. Mikhalev ◽  
Yu. A. Babikova ◽  
N. A. Ryzhakova
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Fetal Development ◽  
Negative Influence ◽  
Preschool Age ◽  
Stage Ii ◽  
Shaping Process ◽  
The Central Nervous System ◽  
Impaired Speech ◽  
In Pregnancy

The ability of memory was investigated in 524 children, aged 4 to 7; with remote consequences of perinatal damage of the central nervous system (CNS). A weak memory ability was detected in 42% of children with dysfunctions of the general and fine motility and in 59% of children with impaired speech. Severe gestosis, anemia in pregnancy (stage II) and a delayed intrauterine fetal development were found to have a negative influence on memory shaping process.

scholarly journals Oxytocin and Pregnancy

2021 ◽  
Author(s):  
Haiwen Yu ◽  
Yuting Cheng ◽  
Yiwen Lu ◽  
Wei Wu ◽  
Qiuqin Tang
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gestational Hypertension ◽  
Smooth Muscles ◽  
Clinical Applications ◽  
Peripheral Tissues ◽  
Oxytocin Receptors ◽  
The Central Nervous System ◽  
Oxytocin Level ◽  
In Pregnancy

Oxytocin, an important neuropeptide, exerts a wide influence on the central nervous system and the peripheral tissues. In the central nervous system, the oxytocin gene expression is mainly shown to be present in neurons in the hypothalamic paraventricular and supraoptic nuclei. Oxytocin gene also transcribes in the peripheral tissues such as uterus, placenta, and amnion. Oxytocin receptors can be founded in many tissues in humans, like the uterine, ovary, testis, kidney, and so on. And just in the same tissue, due to the variation of physiology factors, the amount of oxytocin changes a lot. Oxytocin secretion is closely linked with pregnancy advancing. During labor, the contractions of uterine smooth muscles and oxytocin secretion are inseparable. Moreover, oxytocin is also responsible for stimulating milk ejection after parturition. Oxytocin is associated with many diseases. Poor regulation of oxytocin may cause postpartum depression and infantile autism. In terms of physiology, fatal heart failure and gestational hypertension are concerned with oxytocin level. In this chapter, we will discuss the oxytocin in pregnancy as well as its clinical applications.

Sign in / Sign up

Export Citation Format

Share Document