scholarly journals Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects

2004 ◽  
Vol 92 (2) ◽  
pp. 335-340 ◽  
Author(s):  
Renuka Visvanathan ◽  
Richard Chen ◽  
Michael Horowitz ◽  
Ian Chapman
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Response ◽  
Blood Pressure Response ◽  
Surrogate Marker ◽  
Elderly Subjects ◽  
Glucose Levels ◽  
Healthy Elderly ◽  
Cherry Juice ◽  
Blood Pressure Responses ◽  
Healthy Elderly Subjects

The aim of the present study was to determine the effects on blood pressure response of 50 g carbohydrate drinks with differing glycaemic effects in ten healthy elderly subjects (age >65 years; randomized crossover design). Systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure, heart rate and plasma glucose levels were determined following ingestion of equal volumes (379 ml) of water and 50 g carbohydrate drinks with differing reported glycaemic indices (GI) (surrogate marker for glycaemic effect): (1) low-GI: Apple & Cherry Juice; (2) intermediate-GI: Fanta Orange; (3) high-glucose. Glucose (SBP and DBP P<0·001; MAP P=0·005) and Fanta Orange (SBP P=0·005; DBP and MAP P<0·001) ingestion caused a significant decrease in BP whilst blood pressure increased (SBP P=0·008; MAP P=0·005) from baseline following Apple & Cherry Juice ingestion. Water had no significant effect on postprandial blood pressure. Fanta Orange and Apple & Cherry Juice caused similar (P=0·679) glycaemic effects, which were significantly greater than water, but lower than glucose (P<0·001). There was no significant correlation between the glycaemic effect of the carbohydrate drinks and there was no change in blood pressure from baseline (SBP r −0·123, P=0·509; DBP r −0·051, P=0·784; MAP r −0·069, P=0·712). Apple & Cherry Juice and Fanta Orange had similar glycaemic effects, but differing effects on blood pressure. Therefore, it is unlikely that the glycaemic effect of a drink can be used to predict the subsequent cardiovascular response.

Campodimele Study: Blood Pressure and Heart Rate Pattern in Clinically Healthy Elderly Subjects

1994 ◽  
Vol 11 (6) ◽  
pp. 381-392 ◽  
Author(s):  
P. Cugini ◽  
G. Leone ◽  
P. Lucia ◽  
F. A. Sepe ◽  
A. Pelosio ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Elderly Subjects ◽  
Healthy Elderly ◽  
Heart Rate Pattern ◽  
Healthy Elderly Subjects

scholarly journals Chronotopic and blood pressure response to oral glucose load in chagas' disease

1994 ◽  
Vol 112 (3) ◽  
pp. 602-606 ◽  
Author(s):  
Maria Elena Guariento ◽  
Elza Olga ◽  
Ana Muscelli ◽  
José Antonio Rocha Gontijo
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Response ◽  
Blood Pressure Response ◽  
Serum Insulin ◽  
Oral Glucose ◽  
Oral Glucose Load ◽  
Autonomic Nervous System Dysfunction ◽  
Glucose Levels ◽  
Pressor Responses ◽  
Insulin Activity

Cardiac chronotropic and pressor responses after an oral load of glucose were assessed in sixteen Chagasic subjects and 28 controls by means of blood pressure and pulse rate measurements. Cardiovascular response was correlated with serum insulin and glucose levels. The experiment identified a subgroup of Chagasic subjects (n=8) with a hypoinsulinemic behavior presenting less chronotropic and pressor responses than controls. This may indicate a lower insulin activity and/or an early Autonomic Nervous System dysfunction in this subgroup.

scholarly journals The hypotensive response to oral fat is comparable but slower compared with carbohydrate in healthy elderly subjects

2006 ◽  
Vol 95 (2) ◽  
pp. 340-345 ◽  
Author(s):  
Renuka Visvanathan ◽  
Michael Horowitz ◽  
Ian Chapman
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Area Under The Curve ◽  
Elderly Subjects ◽  
High Fat ◽  
Postprandial Hypotension ◽  
Healthy Elderly ◽  
Hypotensive Response ◽  
Healthy Elderly Subjects

The objective of the present study was to determine the comparative hypotensive responses to drinks containing predominantly fat and carbohydrate (CHO) in healthy elderly subjects. Using a randomised, cross-over study, the participants, twelve elderly subjects, six of them female (72·2 (sd 5·7) years), were investigated. On three separate days, blood pressure (BP) and heart rate were measured following ingestion of 300ml drinks containing: (1) CHO (75g glucose and 93g Polyjoule (CHO polymer) providing 2732kJ (653kcal)); (2) 88% fat (cream blended with milk providing 2732kJ (653kcal)); (3) water. Systolic BP decreased following the CHO drink (P<0·001) and the high-fat drink (P<0·001) but not water; there was no difference in the magnitude of the decrease between the CHO drink and the drink containing fat (13·4v. 15·6mmHg). However, the onset of the fall was slower after the fat-containing drink (13·0v. 26·5min (P=0·01); area under the curve for 0–30min for CHO drink −6·5v. fat-containing drink 125·4 mmHg×min (P=0·043)). We conclude that ingestion of a high-fat drink results in a comparable fall in BP to a CHO drink although the onset is relatively slower. These observations may have implications for the management of postprandial hypotension.

Quantitative aspects of glucose production and metabolism in healthy elderly subjects

Diabetes ◽  
1982 ◽  
Vol 31 (3) ◽  
pp. 203-211 ◽  
Author(s):  
J. J. Robert ◽  
J. C. Cummins ◽  
R. R. Wolfe ◽  
M. Durkot ◽  
D. E. Matthews ◽  
...  
Keyword(s):  
Glucose Production ◽  
Elderly Subjects ◽  
Healthy Elderly ◽  
Healthy Elderly Subjects
Sign in / Sign up

Export Citation Format

Share Document