scholarly journals Comparison of self-reported alcohol intake with the urinary excretion of 5-hydroxytryptophol:5-hydroxyindole-3-acetic acid, a biomarker of recent alcohol intake

2001 ◽  
Vol 85 (5) ◽  
pp. 621-627 ◽  
Author(s):  
Anja Kroke ◽  
Kerstin Klipstein-Grobusch ◽  
Kurt Hoffmann ◽  
Ines Terbeck ◽  
Heiner Boeing ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Urinary Excretion ◽  
Validation Study ◽  
Alcohol Intake ◽  
Dietary Assessment ◽  
Reference Method ◽  
Alcoholic Beverages ◽  
Nutritional Epidemiology ◽  
Assessment Instruments ◽  
Objective Reference

Under-reporting of alcohol intake has been frequently reported. However, due to the lack of an objective reference method, e.g. a biomarker, information about the extent of under-reporting of alcohol intake obtained with dietary assessment instruments is not available. The objective of this study was to compare reported alcohol intake data derived from a 24 h recall with a biomarker of recent alcohol intake, the urinary excretion of 5-hydroxytryptophol (5-HTOL):5-hydroxyindole-3-acetic acid (5-HIAA). Embedded into the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study, Germany, a validation study that collected 24 h recall data and 24 h urine samples was conducted. Cohort study participants (n107) volunteered to participate in this validation study. Among them were five subjects who reported no consumption of alcoholic beverages but had a 5-HTOL:5-HIAA ratio that indicated recent alcohol intake when the clinical cut-off point was taken as a judging criterion. After exclusion of these under-reporters, the Pearson's correlation coefficient between reported alcohol intake and the 5-HTOL:5-HIAA ratio was 0.92 (P<0.0001). Except for low alcohol intake of <0.1 g/kg body mass, a significant increase in 5-HTOL:5-HIAA excretion was observed with increasing amounts of alcohol intake. In conclusion, the 5-HTOL:5-HIAA excretion ratio appears to be a valuable quantitative biomarker of recent alcohol consumption. Denial of alcohol intake can be detected, but for the quantification of under-reporting of alcohol intake 24 h reference data are not yet available. With these data at hand, however, 5-HTOL:5-HIAA could become a biomarker for validation purposes in nutritional epidemiology.

scholarly journals Taking Advantage of the Strengths of 2 Different Dietary Assessment Instruments to Improve Intake Estimates for Nutritional Epidemiology

2012 ◽  
Vol 175 (4) ◽  
pp. 340-347 ◽  
Author(s):  
R. J. Carroll ◽  
D. Midthune ◽  
A. F. Subar ◽  
M. Shumakovich ◽  
L. S. Freedman ◽  
...  
Keyword(s):  
Dietary Assessment ◽  
Nutritional Epidemiology ◽  
Assessment Instruments

scholarly journals Development and use of FFQ among adults in diverse settings across the globe

2011 ◽  
Vol 70 (2) ◽  
pp. 232-251 ◽  
Author(s):  
Sangita Sharma
Keyword(s):  
Dietary Intake ◽  
Sodium Intake ◽  
Dietary Assessment ◽  
Heterocyclic Aromatic Amines ◽  
Nutritional Epidemiology ◽  
High Risk Population ◽  
Assessment Instruments ◽  
Intervention Programme ◽  
Dietary Changes ◽  
Cross Country

In nutritional epidemiology, development of valid dietary assessment instruments specific to populations in diverse settings is of paramount importance. Such instruments are essential when trying to characterise dietary patterns and intake, investigate diet–disease associations, inform and evaluate nutrition interventions, assess nutrient–gene interactions, conduct cross-country comparison studies and monitor nutrition transitions. The FFQ is a relatively inexpensive tool for measuring long-term dietary intake for large populations and for allowing researchers to track dietary changes over time. However, FFQ must be population specific to capture the local diet and available foods. Collecting 24-h dietary recalls and utilising community feedback to build the FFQ ensures that a culturally appropriate instrument is developed. This article presents several examples describing FFQ development and utilisation in different settings globally. In the Canadian Arctic, FFQ were developed and utilised to inform and evaluate a community-based intervention programme, characterise the diet and track dietary changes occurring among Inuit and Inuvialuit, populations experiencing rising rates of chronic disease and likely to be extremely vulnerable to the potential effects of climate change. Another example is an FFQ developed to assess sodium intake and evaluate a sodium reduction trial in a high-risk population in Barbados. An example is provided from Brazil, where an FFQ was developed to assess associations between diet, heterocyclic aromatic amines and colorectal adenoma among Japanese Brazilians and to conduct cross-country comparisons. These and other case studies highlight the diversity in dietary intake between populations and the need for FFQ to be developed to capture this diversity.

scholarly journals Bias in dietary-report instruments and its implications for nutritional epidemiology

2002 ◽  
Vol 5 (6a) ◽  
pp. 915-923 ◽  
Author(s):  
Victor Kipnis ◽  
Douglas Midthune ◽  
Laurence Freedman ◽  
Sheila Bingham ◽  
Nicholas E Day ◽  
...  
Keyword(s):  
Measurement Error ◽  
Validation Studies ◽  
Protein Intake ◽  
Dietary Assessment ◽  
Nitrogen Excretion ◽  
Nutritional Epidemiology ◽  
Assessment Instruments ◽  
Systematic Bias ◽  
Nutritional Studies ◽  
The Impact

AbstractObjective:To evaluate measurement error structure in dietary assessment instruments and to investigate its implications for nutritional studies, using urinary nitrogen excretion as a reference biomarker for protein intake.Design:The dietary assessment methods included different food-frequency questionnaires (FFQs) and such conventional dietary-report reference instruments as a series of 24-hour recalls, 4-day weighed food records or 7-day diaries.Setting:Six original pilot validation studies within the European Prospective Investigation of Cancer (EPIC), and two validation studies conducted by the British Medical Research Council (MRC) within the Norfolk cohort that later joined as a collaborative component cohort of EPIC.Subjects:A sample of approximately 100 to 200 women and men, aged 35–74 years, from each of eight validation studies.Results:In assessing protein intake, all conventional dietary-report reference methods violated the critical requirements for a valid reference instrument for evaluating, and adjusting for, dietary measurement error in an FFQ. They displayed systematic bias that depended partly on true intake and partly was person-specific, correlated with person-specific bias in the FFQ. Using the dietary-report methods as reference instruments produced substantial overestimation (up to 230%) of the FFQ correlation with true usual intake and serious underestimation (up to 240%) of the degree of attenuation of FFQ-based log relative risks.Conclusion:The impact of measurement error in dietary assessment instruments on the design, analysis and interpretation of nutritional studies may be much greater than has been previously estimated, at least regarding protein intake.

scholarly journals Validity of a food frequency questionnaire for the estimation of total polyphenol intake estimates and its major food sources in the Japanese population: the JPHC FFQ Validation Study

2021 ◽  
Vol 10 ◽  
Author(s):  
Nagisa Mori ◽  
Norie Sawada ◽  
Junko Ishihara ◽  
Ayaka Kotemori ◽  
Ribeka Takachi ◽  
...  
Keyword(s):  
Validation Study ◽  
Food Frequency Questionnaire ◽  
Japanese Population ◽  
Alcoholic Beverages ◽  
Food Sources ◽  
Total Polyphenol ◽  
Food Frequency ◽  
Dietary Polyphenols ◽  
Dietary Record ◽  
Polyphenol Intake

Abstract We examine the validity and reproducibility of a food frequency questionnaire (FFQ) in a subsample of participants in the Japan Public Health Center-based Prospective Cohort Study using a database of polyphenol-containing foods commonly consumed in the Japanese population. Participants of the validation study were recruited from two different cohorts. In Cohort I, 215 participants completed a 28-d dietary record (DR) and the FFQ, and in Cohort II, 350 participants completed DRs and the FFQ. The total polyphenol intake estimated from the 28-d DR and FFQ were log-transformed and adjusted for energy intake by the residual method. Spearman correlation coefficients (CCs) between estimates from the FFQ and 28-d DR as well as two FFQs administered at a 1-year interval were computed. Median intakes of dietary polyphenols calculated from the DRs were 1172 mg/d for men and 1024 mg/d for women in Cohort I, and 1061 mg/d for men and 942 mg/d for women in Cohort II. The de-attenuated CCs for polyphenol intake between the DR and FFQ were 0⋅47 for men and 0⋅37 for women in Cohort I and 0⋅44 for men and 0⋅50 for women in Cohort II. Non-alcoholic beverages were the main contributor to total polyphenol intake in both men and women, accounting for 50 % of total polyphenol intake regardless of cohort and gender, followed by alcoholic beverages and seasoning and spices in men, and seasoning and spices, fruits and other vegetables in women. The present study showed that this FFQ had moderate validity and reproducibility and is suitable for use in future epidemiological studies.

Evaluation of dietary assessment instruments in adolescents

2003 ◽  
Vol 6 (5) ◽  
pp. 557-562 ◽  
Author(s):  
Helaine R.H. Rockett ◽  
Catherine S. Berkey ◽  
Graham A. Colditz
Keyword(s):  
Dietary Assessment ◽  
Assessment Instruments

REPRODUCIBILITY AND VALIDITY OF DIETARY ASSESSMENT INSTRUMENTS

1988 ◽  
Vol 128 (3) ◽  
pp. 667-676 ◽  
Author(s):  
PIRJO PIETINEN ◽  
ANNE M. HARTMAN ◽  
ELIINA HAAPA ◽  
LEENA RÄSÄNEN ◽  
JAASON HAAPAKOSKI ◽  
...  
Keyword(s):  
Dietary Assessment ◽  
Assessment Instruments

scholarly journals Studies Regarding the Main Compositional Parameters and Some Volatile Compounds in Spirits from Iaşi Vineyard

2017 ◽  
Vol 74 (2) ◽  
pp. 137
Author(s):  
Lucia Cintia COLIBABA ◽  
Stefan TUDOSE-SANDU-VILLE ◽  
Camelia LUCHIAN ◽  
Andreea POPIRDA ◽  
Marius NICULAUA ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Volatile Compounds ◽  
Octanoic Acid ◽  
Short Chain Fatty Acids ◽  
Raw Material ◽  
Alcoholic Beverages ◽  
Experimental Protocol ◽  
Republic Of Moldova ◽  
The Republic ◽  
Alcoholic Strength

The distillates obtained from wine, both raw and aged, are highly appreciated alcoholic beverages due to the refinement and fineness that characterizes them. Romania’s viticultural conditions are very favourable for these products - which in the last centuries have made regions such as Cognac and Armagnac in France famous. In Romania the aged distillate of wine is called “vinars” and in the Republic of Moldova it is named “divin”. This study analyses how the main compositional parameters and volatile compounds are influenced by the raw material wine, distillation technology, distillation steps, removal of the lower-quality fractions (heads and tails). The raw material used to make the distillates was a mixture of two wines of Fetească albă and Fetească regală, harvest of 2015, from Iasi vineyard. The proposed experimental protocol consisted of the double distillation of a volume of 1000 L of raw material. For the distillation, a simple copper distillery with a deflector was used. From each 10 L of distillate obtained, samples were taken and analysed via gas-chromatography.In the first and second distillation, the largest amounts of acetic acid are found in the head. The highest concentrations of octanoic acid are recorded in tails, as does hexanoic acid. The product obtained after the first distillation recorded an average alcoholic strength of 33.5% vol, which increased after the second distillation, so that the final distillate has an alcoholic strength of 58.5% vol. Concerning the acid profile, the following can be concluded: Acetic acid can be considerably diminished with the removal of the head fractions; Octanoic, hexanoic and decanoic acids fall into the class of short chain fatty acids, can affect the organoleptic qualities but are easily esterify the resulting compounds giving pleasing odour; aging in oak or mulberry wood barrels of crude distillates to achieve the maximum potential is recommended.

Study of pH Effect on the Anaerobic-Aerobic Fermentation of Siwalan (Borassus flabellifer L.) Sap to Produce Acetic Acid

2019 ◽  
Vol 964 ◽  
pp. 209-214
Author(s):  
Elly Agustiani ◽  
Atiqa Rahmawati ◽  
Fibrillian Zata Lini ◽  
Dimas Luthfi Ramadhani
Keyword(s):  
Acetic Acid ◽  
Acid Concentration ◽  
Ethanol Fermentation ◽  
Anaerobic Fermentation ◽  
Sugar Content ◽  
Alcoholic Beverages ◽  
Acetic Acid Concentration ◽  
Acetobacter Aceti ◽  
Aerobic Fermentation ◽  
Acid Product

Siwalan (Borassus flabellifer L.) is a palm family that is widely planted in the Tuban area of ​​East Java. Siwalan sap has a relatively high sugar content of about 10-15 g / 100 ml. The sap is obtained by tapping the inflorescences. In general, siwalan sap is used for fresh drinks or alcoholic beverages with maximum storage in 3 days. Based on the sugar content in the sap of siwalan, acetic acid products can be made through fermentation of glucose to ethanol, then the ethanol is fermented into acetic acid. Acetic acid is widely used as a preservative of food and health drinks. The purpose of this research is to study the effect of ethanol fermentation aerobic pH on acetic acid product. Anaerobic fermentation uses saccharomyces cereviceae to produce ethanol, and aerobic fermentation uses acetobacter aceti for acetic acid production. In aerobic ethanol fermentation using pH 3; 3.5; 4 and 5. The concentration of ethanol was analyzed using GC ULTRA Scientific Gas Chromatography, DSQ II detector, and MS 220 column. Acetic acid produced from the aerobic fermentation process was analyzed using an alkalimetric method. Anaerobic fermentation uses Saccharomyces cereviceae with 1-day log phase, while aerobic fermentation uses acetobacter aceti with a 5 day log phase. Aerobic fermentation to produce acetic acid was observed in 5 days to obtained maximum acetic acid concentration, the highest acetic acid concetration is about 2.595 g/l and yield of acetic acid is obtained 0.519% (b/v) at pH 5. Low acetic acid concentration due to low intitial sugar content in siwalan sap.

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