scholarly journals Alcohol and high-density-lipoprotein cholesterol:a randomized controlled trial

1986 ◽  
Vol 56 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Michael L. Burr ◽  
Ann M. Fehily ◽  
Barbara K. Butland ◽  
Colin H. Bolton ◽  
Robert D. Eastham
Keyword(s):  
Randomized Controlled Trial ◽  
Heart Disease ◽  
High Density Lipoprotein ◽  
Blood Lipids ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Randomized Controlled ◽  
Set Up

1. A randomized controlled trial of cross-over design was set up to examine the effect of alcohol on blood lipids and certain haematological variates relevant to ischaemic heart disease.2. One hundred subjects drank some alcohol for 4 weeks (mean intake 18.4 g/d) and abstained totally for 4 weeks, the order of these periods being randomized.3. Alcohol appeared to produce a rise of 7% in serum high-density-lipoprotein(HDL) cholesterol, probably due to a rise in the HDL2subfraction.4. No significant change was detected in plasma fibrinogen or the other haematoiogical indices.5. These results are consistent with the hypothesis that a moderate intake of alcohol confers some protection against heart disease.

scholarly journals The Effect of Olive Oil (Extra Virgine Olive Oil) and Moderate-Intensity Exercise On The Level of High Density Lipoprotein (HDL) in Male Wistar Strain Rat (Rattus novergicus L) Which Was Given High Fatty Diet

2020 ◽  
Vol 1 (2) ◽  
pp. 27
Author(s):  
Ikhsan Syakban Anwari ◽  
Hendra Sutysna
Keyword(s):  
Heart Disease ◽  
High Density Lipoprotein ◽  
Olive Oil ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Moderate Intensity ◽  
Control Group ◽  
Moderate Intensity Exercise ◽  
Wistar Strain

Background: Dyslipidemia is a condition where there is an abnormal lipid profile in the blood. Modern patterns and lifestyles such as consuming fast food cause excessive fat consumption which can increase the possibility of contracting blood vessel and heart disease. High levels of High Density Lipoprotein (HDL) cholesterol can protect the body against heart disease and stroke, but not many drugs can increase HDL cholesterol levels. Olive oil is an oil that contains 77% Mono Unsaturated Fatty Acid (MUFA) which can reduce LDL cholesterol and increase HDL cholesterol. Objective: To determine the effect of olive oil (Extra Virgine Olive Oil-EVOO) and moderate intensity exercise on high density lipoprotein (HDL) levels in male Wistar strain (Rattus novergicus L) rats fed a high-fat diet. Method: a true experimental research design with a pretest and posttest design with a control group (Pretest and Posttest with Control Group) with simple randomization. Results: There was an increase in HDL levels in the control group (42.50 to 44.50 mg / dl), the olive oil treatment group was (50.83 to 53.33) mg / dL, the moderate intensity exercise treatment group (46.67 to 52 , 00 mg / dl), and the moderate-intensity exercise and olive oil treatment groups (47.50 to 58.67 mg / dl). Conclusion: Extra Virgine Olive Oil, moderate intensity exercise, and Extra Virgine Olive Oil with moderate intensity exercise influence the increase of HDL levels in the blood of male Wistar strain rats fed a high-fatty diet.

Sign in / Sign up

Export Citation Format

Share Document