scholarly journals Improvement of High‐Density Lipoprotein Function in Patients With Early Rheumatoid Arthritis Treated With Methotrexate Monotherapy or Combination Therapies in a Randomized Controlled Trial

2016 ◽  
Vol 69 (1) ◽  
pp. 46-57 ◽  
Author(s):  
Christina Charles‐Schoeman ◽  
Yuen Yin Lee ◽  
Ani Shahbazian ◽  
Xiaoyan Wang ◽  
David Elashoff ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Randomized Controlled Trial ◽  
High Density Lipoprotein ◽  
Early Rheumatoid Arthritis ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
High Density ◽  
Combination Therapies ◽  
Randomized Controlled

scholarly journals Alcohol and high-density-lipoprotein cholesterol:a randomized controlled trial

1986 ◽  
Vol 56 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Michael L. Burr ◽  
Ann M. Fehily ◽  
Barbara K. Butland ◽  
Colin H. Bolton ◽  
Robert D. Eastham
Keyword(s):  
Randomized Controlled Trial ◽  
Heart Disease ◽  
High Density Lipoprotein ◽  
Blood Lipids ◽  
Controlled Trial ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Density ◽  
Randomized Controlled ◽  
Set Up

1. A randomized controlled trial of cross-over design was set up to examine the effect of alcohol on blood lipids and certain haematological variates relevant to ischaemic heart disease.2. One hundred subjects drank some alcohol for 4 weeks (mean intake 18.4 g/d) and abstained totally for 4 weeks, the order of these periods being randomized.3. Alcohol appeared to produce a rise of 7% in serum high-density-lipoprotein(HDL) cholesterol, probably due to a rise in the HDL2subfraction.4. No significant change was detected in plasma fibrinogen or the other haematoiogical indices.5. These results are consistent with the hypothesis that a moderate intake of alcohol confers some protection against heart disease.

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