Holo-analysis of the efficacy of Bio-Mos® in pig nutrition

2006 ◽  
Vol 82 (5) ◽  
pp. 683-689 ◽  
Author(s):  
G. D. Rosen

AbstractThis exploratory holo-analysis of the efficacy of Bio-Mos®, (BM), an outer cell wall derivative of a strain of Saccharomyces cerevisiae, is part of an empirical modelling research programme comparing the efficacies of potential replacements for veterinary prescription-free pronutrient antibiotics in pig production. The data resource was mined from 128 saccharide publications of which 31/97 on BM (1997 to 2003) provided 69 negatively controlled start-to-finish tests from 10 countries (USA 71%) using 3778 pigs(30·5 per treatment). Respective food intake, live-weight gain and food conversion responses of 0·0075 kg/day (0·99%), 0·0145 kg/day (3·58%) and −0·0526 (3·07%) have coefficients of variation of 511, 163 and 229% and beneficial gain and conversion frequencies of 73 and 68%, 54% jointly. Holo-analytical multiple regression models of BM food intake, live-weight gain and food conversion effects using conventional and less stringent probabilities contain significant independent variables for negative control performances, dosage, discontinuous dosage, test duration, year of test, non-USA test, male, grower-finisher, slatted floor, processed food, antibacterial foods, animal protein food, main vegetable protein not soya bean, added oil/fat food and factorial data, which account for 11 to 68% of variations in response. The models quantify differences in research and praxis and indicate areas for future modelling research on BM dose-response relations, effects of ration ingredient and nutrient contents, other saccharide efficacy comparisons, including lactose, and BM comparisons and interactions with other proposed antibiotic replacements.

1973 ◽  
Vol 16 (2) ◽  
pp. 173-177 ◽  
Author(s):  
A. R. Renton ◽  
T. J. Forbes

SUMMARYAn experiment was carried out in which a cereal supplement was given to beef cattle, either in suspension in water or as a dry supplement. There were no significant differences between treatments in live-weight gain, food intake or food conversion ratios. Although there was a tendency for the digestibility coefficients of all constituents to be lower on the diet containing the liquid supplement, the differences were not statistically significant. It is concluded that giving a supplement in suspension has no adverse effect on the utilization of the overall diet and could facilitate mechanization of the feeding operation.


1983 ◽  
Vol 37 (1) ◽  
pp. 137-140 ◽  
Author(s):  
J. A. Woolliams ◽  
G. Wiener

ABSTRACTLambs, 8 weeks of age, the offspring of sires of the Scottish Blackface, East Friesland, Finnish Landrace, Suffolk and Texel breeds mated to Scottish Blackface females as a common maternal breed were fed ad libitum on a concentrate containing barley and fish meal for 14 weeks. Live weight and food intake were measured at intervals of 2 weeks.Live-weight gain varied between sire breeds, Suffolk crosses having the greatest growth rate and the Blackface lambs the least, but there were no significant differences in their food conversion ratios. Food intakes were compared with those predicted by two methods. When the only criteria for prediction were live weight and the metabolizability of the diet the prediction was poor, whereas very accurate agreement was found when the criteria for prediction included consideration of the changes in energy efficiency with food intake and with maturity.


2006 ◽  
Vol 82 (1) ◽  
pp. 117-124 ◽  
Author(s):  
J. J. Hyslop ◽  
R. Keatinge ◽  
D. G. Chapple

AbstractA bull beef finishing experiment was conducted with the objective of comparing physical performance of constrasting genotypes of suckler-bred bull beef animals finished intensively on a cereal-based diet at approximately 12 to 13 months of age. Nine bulls per genotype were drawn from weaned, bull calves born to one of two dam types (Belgian Blue×Holstein/Friesian (BB) or Simmental×Holstein/Friesian (SIM)) and which had been sired by one of two contrasting sire types (Aberdeen Angus (AA) or Charolais (CH)). Bull calves were weaned at approximately 8 months of age and the finishing experiment ran from approximately 9 months of age until slaughter at 12 to 13 months of age. Cereal-based concentrate diets were offered to all bulls on an ad libitum basis throughout the experimental finishing period. Dry matter intake (DMI), live-weight gain (LWG), food conversion ratio (FCR), and carcass slaughter characteristics were quantified.Average daily LWG was 2·07, 2·11, 2·34 and 2·65 kg/day, average FCR was 5·14, 5·06, 4·70 and 4·12 kg DMI per kg LWG and average age at slaughter was 387, 381, 374 and 366 days for the AA/BB, AA/SIM, CH/BB and CH/SIM bulls respectively. These figures showed that CH sired bulls grew faster ( P<0·001), finished at an earlier age ( P<0·01) and had better food conversion ratios ( P<0·01) than AA sired bulls. CH sired bulls also produced heavier carcasses (P<0·001) with better conformation ( P<0·001) than AA sired bulls. Average cold carcass weights (CCW) at slaughter were 309, 318, 348 and 365 kg and average conformation scores (15-point scale) at slaughter were 9·28, 10·28, 12·39 and 12·75 for the AA/BB, AA/SIM, CH/BB and CH/SIM bulls respectively. Finished bulls from SIM dams had higher LWGs (P<0·01) and produced heavier carcasses (P<0·05) than bulls from BB dams. No statistically significant differences in fat score (15-point scale) were seen between any of the breed combinations with fat scores of 7·50, 7·25, 6·75 and 6·75 for the AA/BB, AA/SIM, CH/BB and CH/SIM bulls respectively. No significant differences in average daily food intake were observed between breed combinations in the experiment with average daily DMI being 10·6, 10·6, 11·0 and 10·9 kg/day for AA/BB, AA/SIM, CH/BB and CH/SIM bulls respectively.Overall, there was little evidence to suggest that the rate of bull LWG declined to bring about any meaningful reduction in productivity as average bull live weight increased from approximately 9 months of age until slaughter at 12 to 13 months of age. When finished on a nutrient-rich, cereal-based concentrate diet, excellent animal performance and commercially acceptable carcasses can be produced from the UK suckler herd using genetically superior sires of either traditional UK or continental beef cattle breeds. Results from this study indicate that CH sired bulls out-performed AA sired bulls, especially when produced from SIM cows.


2001 ◽  
Vol 72 (2) ◽  
pp. 351-360 ◽  
Author(s):  
E. C. Whittemore ◽  
I. Kyriazakis ◽  
G.C. Emmans ◽  
B.J. Tolkamp

AbstractAn experiment was carried out on pigs to provide a test of two current conceptual frameworks available for the understanding and prediction of food intake. Framework 1 assumes that food intake will be that which allows potential (genetic) performance to be achieved. If this is not achieved then it is because intake is being constrained. Framework 2 sees food intake as being a consequence of a process of optimization such that biological efficiency (the ratio of net energy ingested to oxygen consumed) is maximized. Both frameworks predict that a reduction in temperature will increase the intake of a high quality food. For a food of low quality framework 2 predicts that intake will also be increased when temperature is decreased while framework 1 predicts that it will not. This difference between the predictions of the two frameworks allows them to be tested by means of an experiment in which foods of different quality were given to animals at different environmental temperatures.Forty pigs were randomly allocated to a control (C) food based on micronized wheat with 13·1 MJ digestible energy (DE) and 232 g crude protein (CP) per kg fresh food, or one of two high bulk foods. The high bulk foods contained either 650 g/kg of unmolassed sugar-beet pulp (SBP) or 650 g/kg of wheat bran (WB). Half the pigs were maintained at a thermoneutral temperature of 22ºC for 14 days followed by a cold temperature of 12ºC for 14 days. The other half were maintained at 12ºC for a period of 14 days followed by a temperature of 22ºC for 14 days. Food intake was recorded daily and live weight twice weekly.There was a highly significant food ✕ temperature interaction ( P < 0·001) for food intake. A reduction in temperature resulted in an increase in food intake on C and WB but had no effect on the intake of SBP. There was a highly significant effect of both temperature and food on intake ( P < 0·001). A reduction in temperature resulted in a significant increase in food intake, intake on WB was higher than that of either C or SBP. There was no overall effect of temperature on live-weight gain although a reduction in temperature resulted in a non-significant increase in the gain of C and reduction in the gain of WB and SBP. There was a highly significant effect of food ( P < 0·001) on live-weight gain, as gain on C was higher than that on either WB or SBP.The results of the experiment were in agreement with the predictions set forward by the first framework that growing pigs are eating to achieve maximum performance subject to constraints.


1985 ◽  
Vol 41 (2) ◽  
pp. 207-217 ◽  
Author(s):  
I. D. Johnsson ◽  
I. C. Hart ◽  
B. W. Butler-Hogg

ABSTRACTIn crossbred female lambs given a concentrate diet ad libitum between 8 and 20 weeks of age, daily subcutaneous injections of 0·1 mg bovine pituitary growth hormone (GH) per kg live weight increased daily live-weight gain (347 v. 284 g/day; P < 0·01; no. = 8), food conversion efficiency (3·94 v. 4·49 kg dry matter per kg gain; P < 0·01) and greasy fleece weight (1·49 v. 0·99 kg; P < 0·001). The increase (4·8 kg) in final live weight was due primarily to an increase in the non-carcass components of the body (3·5 kg), with little effect on carcass weight (1·3 kg). However, bovine GH treatment markedly increased the weights of lean tissue (11·4 v. 9·2 kg; P < 0·001) and bone (2·8 v. 2·4 kg; P < 0·001) and moderately reduced the weight of fat (7·0 v. 8·0 kg; P < 0·10) in the carcass. The bovine GH treatment raised plasma concentrations of immunoreactive GH within the physiological range for about 16 h each day and significantly increased mean plasma concentrations of insulin and prolactin. Daily injection of 1 mg bromocriptine had no effect on daily live-weight gain, food conversion efficiency or carcass composition. This treatment markedly reduced plasma concentrations of prolactin but also significantly reduced insulin concentrations. When given in combination with bovine GH, bromocriptine reduced the GH-induced stimulation of insulin concentration and tended to decrease the effects of GH on food conversion efficiency and growth. This interaction was significant only for the effects on greasy fleece and skin weights (P < 0·01).


1970 ◽  
Vol 12 (4) ◽  
pp. 543-549 ◽  
Author(s):  
W. Rutter

SUMMARY1. Seventy-two Blackface ewes with 96 Greyface (Border Leicester ♂ × Blackface ♀) lambs were allocated to three groups. Twenty-four ewes with 32 suckling lambs were set-stocked on 2·4 hectares (ha) of grass (A); 32 lambs were weaned and set-stocked on 2·4 ha of grass (B) and 32 lambs were weaned, housed and given concentrates (C). Beef cows with calves were used to control the grass in the two grazing groups.2. The average initial live weight of the lambs was 18 kg. Treatments had a significant effect on performance, the live-weight gains per lamb over the initial 35 days being 11·2, 9·1 and 5·9 kg for groups A, B and C respectively. The total gains over 70 days, when the suckled lambs (A) were weaned, were 17·6, 15·5 and 14·3 kg.3. The total live-weight gain per ha from lambs and calves over 88 days was higher on treatment B than on treatment A. The lambs weaned on to grass took 9 days longer than the suckled lambs to reach a slaughter weight of 42 kg and had significantly poorer killing-out percentages.4.The lambs given concentrates had an overall food conversion efficiency of 4·89 kg concentrates per kg live-weight gain.


1997 ◽  
Vol 64 (3) ◽  
pp. 541-546 ◽  
Author(s):  
A. J. Hanlon ◽  
S. M. Rhind ◽  
H. W. Reid ◽  
C. Burrells ◽  
A. B. Lawrence

AbstractAt weaning at 3 months of age (week 1), 30 red deer hind calves were housed in six groups of five animals at a stocking density of 1·5 m2 per head and maintained in these groups for 4 weeks. At the start of week 5, all calves were immunized with ovalbumin (OVA). Fifteen calves, from three groups, selected at random, were transferred to individual pens which restricted visual and tactile contact with others (ISO) while the remaining animals were kept in their groups (GP). The behaviour, food intake, live-weight gain, antibody and lymphocyte responses in vitro to OVA and lymphocyte responses in vitro to the non-specific mitogen, concanavalin A (ConA), of all calves were assessed in each of weeks 5 to 9. Isolated calves had a lower mean live-weight gain than GP calves (P < 0·001), although there were no differences in food intake. Significantly more time was spent lying (P < 0·001) but less time feeding (P < 0·05) and self-grooming (P < 0·001) by ISO than by GP calves. There was no significant difference between ISO and GP calves in the cortisol response to an ACTH challenge test (10 i.u.) at week 11. Lymphocyte responses and antibody titres to OVA were lower in GP than in ISO calves at weeks 7 (P < 0·05) and 8 (P < 0·05), respectively. In contrast, GP calves had greater lymphocyte responses to the non-specific mitogen, ConA, in weeks 7 (P < 0·05) and 10 (P < 0·001) but not in week 9 compared with ISO calves. Differences in lymphocyte stimulation were attributed to the non-specific mitogenic nature of ConA. Factors such as agonistic interactions evident in group housing may have compromised the antibody and lymphocyte responses to OVA by GP calves but conversely the lack of social contact may have also suppressed behavioural activity in ISO calves.


1967 ◽  
Vol 9 (4) ◽  
pp. 501-508 ◽  
Author(s):  
D. A. R. Davies ◽  
J. B. Owen

1. Investigations into possible ways of rearing artificially the lambs surplus to the ewe's capacity are described and the results discussed.2. A ewe-milk replacer with a high fat content was used from 2 days of age until weaning at 11.4 kg live weight. Two levels of milk feeding, restricted and ad libitum, were given in the second year. Significant differences were observed in live weight gain per day, milk consumption per kg live weight gain and solid food intake prior to weaning. Live weight gain and solid food intake in the period immediately after weaning also differed markedly. Sex and birth weight had little effect on performance.3. Food costs were lower on the restricted level of milk feeding than on the ad libitum level.


1993 ◽  
Vol 56 (3) ◽  
pp. 341-349 ◽  
Author(s):  
M. F. J. van Houtert ◽  
R. A. Leng

AbstractEighty castrated male lambs were allocated to either an initial slaughter group (no. = 16) or one of eight treatment groups (no. = 8). Ammoniated barley straw was offered ad libitum. This was supplemented with sodium (Na) propionate (0 or 20 g/day), formaldehyde-treated casein, (protected casein, 0 or 50 g/day) and/or calcium (Ca) salts of long-chain fatty acids (Ca soap, 0 or 30 g/day), as a factorial design. Measurements were made of food intake, live-weight gain and wool growth, rumen fluid parameters and changes in body composition over a period of 155 days.Food intake (g dry matter per kg live weight) was lower in the groups supplemented with Ca soap and Na propionate. Fleece-free live-weight gain was increased by supplementation with protected casein and Ca soap, but was not affected by Na propionate. Supplementation with protected casein increased wool yield. Adjusted means for water, protein and ash content of the body (adjusted to mean fleece/digesta-free body weight at slaughter of 27·1 kg) were affected significantly by the second-order interaction between the supplements. Adjusted body water and protein mass were lower when Na propionate was given alone or with Ca soap and protected casein. Fat mass tended to be higher under those conditions. Supplementation with Ca soap increased adjusted fat and gross energy contents and decreased adjusted protein and water mass. Supplementation with protected casein decreased total body fat and increased adjusted protein mass in the body. The partitioning of water, protein, fat, ash and energy between the carcass and non-carcass residues was affected to a small extent also. These results demonstrate interactive effects of the supplements used, on nutrient partitioning in lambs offered straw-based diets.


1965 ◽  
Vol 7 (2) ◽  
pp. 253-261 ◽  
Author(s):  
D. Horrocks ◽  
A. W. A. Burt ◽  
D. C. Thomas ◽  
M. C. Lancaster

SUMMARY1. The effects of including small quantities of groundnut meal heavily contaminated with aflatoxin in the diets of calves and fattening cattle were studied.2. Inclusion of 4% or 8% of the toxic meal in concentrate diets for early weaned calves significantly depressed live-weight gain and food intake prior to 3 months. The depression in live-weight gain was due to lowered food intake and to impaired food utilisation.3. Inclusion of 4% to 12% toxic meal in meal mixtures consumed at 12–13 lb. daily for 20 weeks had no effect on the performance of fattening cattle.4. Enlarged hepatic cell nuclei were found at slaughter in livers from calves which had received toxic meal and the incidence of these slight lesions varied with toxic meal intake. A very small incidence of similar lesions occurred in fat cattle fed on the highest level of toxic meal.5. Complete exclusion of groundnut meals containing appreciable amounts of aflatoxin from the diets of calves and dairy cows, and its very limited use in diets for store and fattening cattle is recommended.


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