Additive and heterotic breed effects in the genetic evaluation of pig sire breeds

2006 ◽  
Vol 82 (4) ◽  
pp. 455-462 ◽  
Author(s):  
J. Wolf ◽  
D. Peškovičová ◽  
E. Žáková ◽  
E. Groeneveld

AbstractThe data sets consisted of field performance data from 54 848 purebred and 16 175 crossbred animals (Czech data set, CZ) and 16 610 purebred and 9 228 crossbred animals (Slovak data set, SK). Animals from the following breeds were included: Duroc, Hampshire, Piétrain, sire line of Large White (CZ) or Yorkshire (SK), Czech Meat pig (CZ) or Slovak Meat pig (SK), Belgian Landrace (SK). Two-trait animal models were calculated for average daily gain from birth to the end of the field test (ADG) and lean meat content (LM, only in CZ) or backfat thickness (BF, only in SK). The models included additive breed and breed heterotic effects. Piétrain was the breed with the highest LM and the lowest BF. The additive genetic breed effect was about 1·5% LM (CZ) in comparison with Large White or −0·4 mm BF (SK) in comparison to Yorkshire. The sire line of Large White (CZ) or the Yorkshire breed (SK) clearly exceeded all the remaining sire breeds in ADG (on average by 30 to 50 g/day). There was a clear tendency to negative heterosis in LM in all crossbred combinations (CZ). In BF, heterotic effects between −0·2 mm and +0·3 mm were estimated, mostly not being significant (SK). The estimates of the heterotic effects for ADG were positive throughout. Higher values up to 40 g/day (7%) were observed in the Czech data set. Though heterotic breed effects are of some importance especially for ADG, their inclusion in the equations for breeding value estimation will have only a minor impact on the predicted breeding values.

Author(s):  
Pavla Chalupová ◽  
T. Urban ◽  
A. Knoll

This research focused on recently described MspI and VspI SNPs in interleukin-18 gene and their association with selected performance traits (backfat thickness; lean meat content, average daily gain from birth, average daily gain in test, breeding value for average daily gain, for lean meat content, for reproduction and total breeding value) in a population of 344 Czech Large White sows. Both SNPs were genotyped by PCR-RFLP. In this work, these polymorphisms were associated with backfat thickness and lean meat content. Animals with genotype AA (MspI SNP) had significantly (P < 0.05) lower backfat thickness and higher lean meat content (0.77 ± 0.02 and 62.16 ± 0.23, resp.) compared to GA (0.83 ± 0.02 and 61.40 ± 0.18, resp.). Animals with genotype AA (VspI SNP) had significantly (P < 0.05) lower lean meat content and higher backfat thickness (61.10 ± 0.36 and 0.85 ± 0.03, resp.) compared to GA (62.02 ± 0.16 and 0.77 ± 0.02, resp.). No association between IL-18 polymorphisms and other performance traits was found. Our study revealed that IL-18 could be candidate gene for backfat thickness and lean meat content in pigs.


2009 ◽  
Vol 54 (No. 10) ◽  
pp. 443-447 ◽  
Author(s):  
J. Zrůstová ◽  
A. Knoll ◽  
T. Urban ◽  
S. Čepica

Visfatin encoded by the <I>NAMPT</I> gene <I>(nicotinamide phosphoribosyltransferase,</I> formerly also known as <I>PBEF – pre-B cell colony-enhancing factor</I>) is suggested to play a role in lipid metabolism and pathophysiology of diabetes mellitus type 2. A new microsatellite <I>SCZ004</I> was detected within intron 9 of the <I>NAMPT</I> gene. In Czech Large White (<I>n</I> = 95) frequencies of alleles <I>282, 286, 287, 299</I>, and <I>304</I> were 0.02, 0.39, 0.07, 0.04, and 0.48, respectively. Allele <I>286</I> was predominant also in Landrace (<I>n</I> = 11) and Black Pied Prestice (<I>n</I> = 11) breeds. Association analysis was carried out between previously reported SNP AM999341:g.669T>C in intron 9 of the <I>NAMPT</I> gene and backfat thickness, average daily gain and lean meat content in Czech Large White (<I>n</I> = 215), Black Pied Prestice (<I>n</I> = 96) and Landrace (<I>n</I> = 105). The <I>CC</I> genotype was associated with higher backfat thickness (<I ≤ 0.01) in Black Pied Prestice, however in Czech Large White <I>CC</I> was associated with lower backfat thickness when compared to <I>TT</I> and <I>CT</I> genotypes (<I ≤ 0.05). In Czech Large White, <I>CC</I> genotype was associated with higher lean meat content when compared to <I>CT</I> (not significant) and <I>TT</I> genotype (<I ≤ 0.05) while in Landrace <I>CC</I> had the lowest lean meat content when compared to <I>CT</I> and <I>TT</I> genotypes but only the difference between <I>CC</I> and <I>CT</I>T was statistically significant (<I ≤ 0.05). In Black Pied Prestice no association with lean meat content was found. Average daily gain was not associated with the SNP in any breed.


2009 ◽  
Vol 54 (No. 8) ◽  
pp. 359-364 ◽  
Author(s):  
Z. Vykoukalová ◽  
A. Knoll ◽  
S. Čepica

Perilipin, encoded by the <I>PLIN</I> gene, is a lipid droplet-associated phosphoprotein that functions as a key regulator of triacylglycerol storage and hydrolysis in adipocytes. In this study, structure and variability of the porcine <I>PLIN</I> gene were characterised. PCR fragments encompassing exons 1 to 9 and interspersed introns were sequenced and the obtained sequence was deposited in EMBL/GenBank/DDBJ databases (AM931171). Seven silent polymorphisms and one nonsynonymous polymorphism were detected in the coding sequence. The nonsynonymous polymorphism g.627G>A causing an amino acid substitution p.Val3Ile was found only in Meishan and Meishan × Piétrain cross. Associations were studied between loci g.4119A>G and g.7966T>C, and average daily gain (ADG), backfat thickness (BFT) or lean meat content (LMC) in 166 gilts from two herds. Due to supposed complete linkage disequilibrium between loci g.4119A>G and g.7966T>C only genotype combinations <I>AA-TT, AG-TC</I> and <I>GG-CC</I> were detected. A significant difference (<I>P</I> = 0.0290) between <I>GG-CC</I> and <I>AG-TC</I> genotype combinations for BFT in herd 2 and a suggestive difference (<I>P</I> = 0.0516) between <I>GG-CC</I> and <I>AA-TT</I> genotypes for ADG in herd 1 were detected.


2020 ◽  
Vol 60 ◽  
pp. 5-11
Author(s):  
I. V. Verbuch ◽  
H. V. Bratkovska

Goal. To accelerate the selection process and create populations of pigs with high level of productivity to assess the most effective modern methods breeding value of large white pigs in the SE "DG" Pasichna "Institute of Feed and Agriculture Podillya NAAS" Starosinyavsky district of Khmelnytsky region on the basis of a combined assessment of repair young for their own productivity and assessment meat qualities by MD Berezovsky and B. Tyler and the most promising method BLUP. Methods. Comparison, zootechnical and biometric analyzes. Results. The breeding value of pigs of large white breed of the breeding farm of SE "Pasichna" ICSGP NAAS "Starosinyavsky district of Khmelnytsky region by modern effective methods, namely: BLUP. According to the average indicators of the combined assessment of own productivity of animals at control fattening, taking into account their live weight on the date of birth and weaning, average daily gain, live weight and age of 100 kg, body length and fat thickness, boars significantly outweighed pigs. Compared with pigs, their live weight at the date of birth and weaning (at the age of 30 days) was higher by 0.1 and 0.81 kg. The age of reaching a live weight of 100 kg exceeded by 5.43 days, the average daily gain of 0.016 kg. Live weight and body length of pigs on the date of fat thickness measurement was greater by 4.04 kg and 1.03 cm. Lifetime fat thickness at three measurement points at the level of 6–7 thoracic vertebrae, on the buttocks and in the midpoint of the back between withers and buttocks was thinner by 0.92; 0.94 and 1.06 mm. Evaluation indices of fattening and meat qualities by growth energy and fat thickness (Ia) and average daily gain and fat thickness (Iv) in boars indicate their higher level by 2.07 and 7.67 points compared to pigs and are equal to, respectively, 95.12 ± 1.95 and 152.96 ± 2.38 points. The coefficient of variability (Cv, %) of indicators of own productivity and estimated indices of fattening and meat qualities of repair boars ranged from 1.92% (body length on the date of fat thickness measurement, cm) to 15.12% (age of live weight 100 kg, days), repair pigs – from 4.63% (body length on the date of fat thickness measurement, cm) to 28.19% (index of assessment for growth energy and fat thickness, (Ia), points). The best average values of indicators of breeding value of animals are found on the basis of modern, most promising method BLUP, because it is considered in terms of mathematics, statistics and selection is the most accurate, well-founded, has the best theoretical basis and the lowest error variance. The average value of the BLUP index (parent lines) for boars of large white breed is 101.71 ± 1.681, pigs – 96.94 ± 0.724 points. At the same time, boars outweighed pigs by 4.77 points. The most positive correlation between live weight of piglets at weaning with their body length (r = 0.16), average daily gain (r = 0.19) and fat thickness (r = 0.24), the average correlation between the indices of fattening and meat qualities according to MD Berezovsky and B. Tyler (r = 0.56) P > 0.99 and the weak correlation between live weight of piglets at weaning and the BLUR index (r = 0,21) P > 0.99. It should be noted that there are almost no correlations between the fattening and meat quality indices of pigs and the BLUP index. Conclusions. In the conditions of breeding and specialized farms for the production of commercial pork in the region, to determine the breeding value of animals for further reproduction of their own herd and sale to other breeding farms of Ukraine, to systematically assess repair young animals for their own productivity and clear qualities of pigs and the most perfect BLUP index.


2011 ◽  
Vol 56 (No. 8) ◽  
pp. 337-344 ◽  
Author(s):  
F. Weisz ◽  
T. Urban ◽  
P. Chalupová ◽  
A. Knoll

&nbsp;In this study association analyses were performed between genes tagged SNP (IGF2, NAMPT, DGAT1, MYF4, MC3R, MC4R and MYOD1), performance traits (backfat thickness, lean meat content, average daily gain from birth to the end of the test, average daily gain in test) and estimated breeding values (EBVs) in a population of Czech Large White sows (n = 101). Genotyping of all SNPs was performed by SNapShot with the exception of SNP within NAMPT gene for which HpaII PCR-RFLP assay was used. The following significant associations between genes tagged SNPs and traits or EBVs were found out: DGAT1 &ndash; lean meat content (AG &gt; AA, P &le; 0.05), MC4R &ndash; EBV for lean meat content (GG &gt; AA, P &le; 0.05; GG &gt; AG, P &le; 0.05), IGF2 &ndash; EBV for reproduction (piglets born alive in the second and subsequent parity) (AG &gt; AA, P &le; 0.05) and total EBV (AG &gt; AA, P &le; 0.01) and MC3R &ndash; EBV for average daily gain (CT &gt; TT, P &le; 0.05).


1996 ◽  
Vol 62 (3) ◽  
pp. 479-487 ◽  
Author(s):  
M. H. Fahmy

AbstractRecords ivere collected on Romanov (R), Finnsheep (F), and Booroola Merino (B); first cross; and backcrosses of these breeds with a new synthetic breed of Dorset, Leicester and Suffolk (DLS). The data covered the period from the birth of ewes to weaning of their progeny. The heaviest lambs at birth were the B backcross and R first and backcrosses (4·1 to 4·0 kg) and the lightest were pure R (3·0 kg). The fastest pre-weaning average daily gain was that ofR crosses. R purebreds were more fertile (109%, P < 0·01) than F (81%) and B (62%). They were also more prolific at birth and at weaning (2·44, 2·13) than F (2·04, 1·71, P < 0·01) and B (2·36, 2·09, P > 0·05) purebreds, respectively. Similarly, first-cross R ewes were more prolific than first-crosses of F and B (1·99 v. 2·86 and 1·70), also backcross R ewes were more prolific than backcrosses ofF and B (1·63 v. 1·45 and 1·42, P > 0·05), respectively. R first-cross ewes had heavier litters (6·31 and 26·1 kg) than B (5·17 and 20·3 kg, P>0·01) and F (5·52 and 24·4 kg) at birth and at day 50. The lambs born to DLS ewes were the heaviest at birth and at day 50 compared with those from prolific ewes. Fleece weight in B and its crosses was significantly higher than in R. Crosses showed generally positive heterotic effect in weights, prolificacy and wool production compared with pure breeds. In two data sets, additive direct effect ofR was higher than that ofF at birth (by 0·11 and 0·10 kg) and at day 50 (by 0·57 and 0 kg) but was similar at day 100 and day 365. The additive direct effect of both R and F was non-significantly different to that of B at birth in both data sets, but in only one data set was it higher (P < 0·001) at day 50 (by 2·29 and 1·72 kg), at day 100 (by 5·24 and 5·30 kg) and at day 365 (by 8·7 and 8·4 kg, respectively). Maternal direct effects ofR was higher (P < 0·05) than F in lamb weights at day 1 and 50, and higher than B in lamb weight at day 50. Individual heterosis between both R and F and DLS were -3·7 and -3·6% in weight at birth, 1·46 and 2·09% in weight at day 50 respectively. The corresponding maternal heterosis were, -2·9, -5·2, 1·46 and -0·02%.


2004 ◽  
Vol 78 (1) ◽  
pp. 61-66 ◽  
Author(s):  
A. T. Kanengoni ◽  
K. Dzama ◽  
M. Chimonyo ◽  
J. Kusina ◽  
S. M. Maswaure

AbstractA study was conducted to compare the performance of Mukota, Large White (LW) and LW ✕ Mukota F1pigs given increasing levels of maize cob meal. Sixteen female weaners of each genotype were given, ad libitum, diets containing 0, 100, 200 and 300 g maize cob meal per kg of diet for 14 weeks. The diets were designed to contain similar levels of protein (ca. 160 g crude protein per kg) and energy (ca. 9 MJ metabolizable energy per kg). Average daily food intake per unit metabolic body weight (ADFI per kg M0·75), average daily gain (ADG) and food conversion ratio (FCR) were determined. The pigs were slaughtered and cold dressed mass (CDM) and backfat thickness were determined for each pig. The ADFI per kg M0·75was similar among the four diets for the three genotypes. The rate of decline in ADG was higher (P < 0·05) in the LW than in the other two genotypes. The FCR in the Mukota was poorer (P < 0·05) than that in the LW and the F1crosses. The Mukota had the highest (P < 0·05) backfat thickness (K5 and K7·5) values of the three genotypes across the four diets, followed by the F1crosses. The CDM values for the LW and the F1crosses were similar and were higher (P < 0·05) than those for the Mukota. The findings indicate that F1crosses and the Mukota were better able to utilize diets containing high levels of maize cob meal than LW pigs.


2003 ◽  
Vol 77 (1) ◽  
pp. 67-72 ◽  
Author(s):  
D. N. D’Souza ◽  
B. P. Mullan

AbstractSixty crossbred (Large White × Landrace × Duroc) pigs were used to compare the growth performance, carcass and pork quality characteristics of entire, surgically castrated and immunologically castrated male pigs from two Western Australian commercial genotypes (genotype A : ‘lean’ genotype and genotype B : propensity for increased subcutaneous fat deposition). Pigs from genotype B had a higher average daily gain and a superior food conversion ratio compared with pigs from genotype A. Entire males had lower backfat compared with surgically and immunologically castrated male pigs. Pork from entire males was drier, tougher and had lower overall acceptability scores compared with surgically or immunologically castrated male pigs. Pork from genotype A pigs had a lower m. longissimus thoracis (LT) ultimate pH and higher drip loss compared with pork from genotype B pigs. However, consumer taste panel assessment indicated that pork from genotype A pigs was more tender, had higher juiciness and overall acceptability scores compared with pork from genotype B pigs. Within genotype A, the consumer taste panel preferred pork from surgically castrated pigs compared with either entire or immunologically castrated pigs. Within genotype B, the consumer taste panel preferred pork from immunologically castrated pigs compared with either entire or surgically castrated male pigs. These results indicate that interactions between genotype and castration method can significantly influence eating quality of pork.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 42-42
Author(s):  
Breno Fragomeni ◽  
Zulma Vitezica ◽  
Justine Liu ◽  
Yijian Huang ◽  
Kent Gray ◽  
...  

Abstract The objective of this study was to implement a multi-trait genomic evaluation for maternal and growth traits in a swine population. Phenotypes for preweaning mortality, litter size, weaning weight, and average daily gain were available for 282K Large White pigs. The pedigree included 314k individuals, of which 35,731 were genotyped for 45K SNPs. Variance components were estimated in a multi-trait animal model without genomic information by AIREMLF90. Genomic breeding values were estimated using the genomic information by single-step GBLUP. The algorithm for proven and young (APY) was used to reduce computing time. Genetic correlation between proportion and the total number of preweaning deaths was 0.95. A strong, positive genetic correlation was also observed between weaning weight and average daily gain (r = 0.94). Conversely, the genetic correlations between mortality and growth traits were negative, with an average of -0.7. To avoid computations by expensive threshold models, preweaning mortality was transformed from a binary trait to two linear dam traits: proportion and a total number of piglets dead before weaning. Because of the high genetic correlations within groups of traits, inclusion of only one growth and one mortality trait in the model decreases computing time and allows for the inclusion of other traits. Reduction in computing time for the evaluation using APY was up to 20x, and no differences in EPD ranking were observed. The algorithm for proven and young improves the efficiency of genomic evaluation in swine without harming the quality of predictions. For this population, a binary trait of mortality can be replaced by a linear trait of the dam, resulting in a similar ranking for the selection candidates.


2006 ◽  
Vol 38 ◽  
pp. 77-86 ◽  
Author(s):  
B. Peinado ◽  
J.L. Vega-Pla ◽  
M.A. Martínez ◽  
M. Galián ◽  
C. Barba ◽  
...  

SummaryThe Chato Murciano is the only surviving breed of pig of those historically farmed in the region of Murcia for their quality meat. At present, it is on the verge of extinction, having a population of only 260 reproductive animals. This paper describes the genetic studies made in the conservation and recovery programme of this breed of pig. A study of the morphological characterization of these animals was carried out first, measuring thirteen quantitative and six qualitative variables in a sample of 24 adult animals, 8 males and 16 females.Subsequently, investigation was made of the consanguinity of the individuals and of the population as well as the future influence of inbreeding in each generation. Finally, the accuracy and precision of the heterozygote-excess method was evaluated using two data sets from the Chato Murciano pig. One data set is an original population and the other is a F3+F4+F5 generation of a line created from mating a Chato Murciano female with a Large White boar as part of an absorption programme based on backcrosses with Chato Murciano boars.


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