scholarly journals Chondroitinase-mediated Degradation of Rare 3-O-Sulfated Glucuronic Acid in Functional Oversulfated Chondroitin Sulfate K and E

2007 ◽  
Vol 282 (51) ◽  
pp. 36895-36904 ◽  
Author(s):  
Duriya Fongmoon ◽  
Ajaya Kumar Shetty ◽  
Basappa ◽  
Shuhei Yamada ◽  
Makiko Sugiura ◽  
...  
Keyword(s):  
Chondroitin Sulfate ◽  
Glucuronic Acid ◽  
Oversulfated Chondroitin Sulfate ◽  
Sulfated Glucuronic Acid

scholarly journals Novel Sulfated Oligosaccharides Containing 3-O-Sulfated Glucuronic Acid from King Crab Cartilage Chondroitin Sulfate K

1996 ◽  
Vol 271 (43) ◽  
pp. 26745-26754 ◽  
Author(s):  
Kazuyuki Sugahara ◽  
Yukako Tanaka ◽  
Shuhei Yamada ◽  
Nobuko Seno ◽  
Hiroshi Kitagawa ◽  
...  
Keyword(s):  
Chondroitin Sulfate ◽  
Glucuronic Acid ◽  
King Crab ◽  
Sulfated Oligosaccharides ◽  
Sulfated Glucuronic Acid

Antibodies to Sulfated Glucuronic Acid Containing Glycosphingolipids in Neuropathy Associated with Anti-Mag Antibodies and in Normal Individuals

1988 ◽  
Vol 540 (1 Advances in N) ◽  
pp. 442-444
Author(s):  
SCOTT McGINNIS ◽  
TATSUO KOHRIYAMA ◽  
ROBERT K. YU ◽  
MICHAEL A. PESCE ◽  
NORMAN LATOV
Keyword(s):  
Glucuronic Acid ◽  
Normal Individuals ◽  
Sulfated Glucuronic Acid

Oversulfated chondroitin sulfate-E binds to BMP-4 and enhances osteoblast differentiation

2008 ◽  
Vol 217 (3) ◽  
pp. 769-777 ◽  
Author(s):  
Tatsuya Miyazaki ◽  
Satoshi Miyauchi ◽  
Akira Tawada ◽  
Takahisa Anada ◽  
Satoshi Matsuzaka ◽  
...  
Keyword(s):  
Chondroitin Sulfate ◽  
Osteoblast Differentiation ◽  
Chondroitin Sulfate E ◽  
Oversulfated Chondroitin Sulfate

Biosynthesis of chondroitin sulfate. Microsomal acceptors of sulfate, glucuronic acid, and N-acetylgalactosamine

Biochemistry ◽  
1973 ◽  
Vol 12 (20) ◽  
pp. 3898-3903 ◽  
Author(s):  
Martha E. Richmond ◽  
Silvana DeLuca ◽  
Jeremiah E. Silbert
Keyword(s):  
Chondroitin Sulfate ◽  
Glucuronic Acid

scholarly journals Unexpected loss of stereoselectivity in glycosylation reactions during the synthesis of chondroitin sulfate oligosaccharides

2019 ◽  
Vol 15 ◽  
pp. 137-144 ◽  
Author(s):  
Teresa Mena-Barragán ◽  
José L de Paz ◽  
Pedro M Nieto
Keyword(s):  
Chondroitin Sulfate ◽  
Exploratory Study ◽  
Glucuronic Acid ◽  
Building Blocks ◽  
Significant Loss ◽  
Efficient Synthesis ◽  
Substitution Pattern ◽  
The Impact

Here, we present an exploratory study on the fluorous-assisted synthesis of chondroitin sulfate (CS) oligosaccharides. Following this approach, a CS tetrasaccharide was prepared. However, in contrast to our previous results, a significant loss of β-selectivity was observed in [2 + 2] glycosylations involving N-trifluoroacetyl-protected D-galactosamine donors and D-glucuronic acid (GlcA) acceptors. These results, together with those obtained from experiments employing model monosaccharide building blocks, highlight the impact of the glycosyl acceptor structure on the stereoselectivity of glycosylation reactions. Our study provides useful data about the substitution pattern of GlcA units for the efficient synthesis of CS oligomers.

Sign in / Sign up

Export Citation Format

Share Document