scholarly journals Cell Type-specific Post-transcriptional Regulation of Production of the Potent Antiangiogenic and Proatherogenic Protein Thrombospondin-1 by High Glucose

2007 ◽  
Vol 283 (9) ◽  
pp. 5699-5707 ◽  
Author(s):  
Sanghamitra Bhattacharyya ◽  
Tina E. Marinic ◽  
Irene Krukovets ◽  
George Hoppe ◽  
Olga I. Stenina
Keyword(s):  
Transcriptional Regulation ◽  
High Glucose ◽  
Cell Type ◽  
Thrombospondin 1 ◽  
Cell Type Specific ◽  
Post Transcriptional Regulation

Cell type-specific transcriptional regulation of the drosophila FMRFamide neuropeptide gene

Neuron ◽  
1993 ◽  
Vol 10 (2) ◽  
pp. 279-291 ◽  
Author(s):  
Lynne E. Schneider ◽  
Marie S. Roberts ◽  
Paul H. Taghert
Keyword(s):  
Transcriptional Regulation ◽  
Cell Type ◽  
Cell Type Specific

scholarly journals Post-transcriptional control of cellular differentiation by the RNA exosome complex

2020 ◽  
Vol 48 (21) ◽  
pp. 11913-11928
Author(s):  
Isabela Fraga de Andrade ◽  
Charu Mehta ◽  
Emery H Bresnick
Keyword(s):  
Cellular Differentiation ◽  
Transcriptional Control ◽  
Cell Type ◽  
Protein Coding ◽  
Regulatory Machinery ◽  
Regulatory Complex ◽  
Cell Type Specific ◽  
Rna Exosome ◽  
Post Transcriptional Regulation ◽  
Exosome Complex

Abstract Given the complexity of intracellular RNA ensembles and vast phenotypic remodeling intrinsic to cellular differentiation, it is instructive to consider the role of RNA regulatory machinery in controlling differentiation. Dynamic post-transcriptional regulation of protein-coding and non-coding transcripts is vital for establishing and maintaining proteomes that enable or oppose differentiation. By contrast to extensively studied transcriptional mechanisms governing differentiation, many questions remain unanswered regarding the involvement of post-transcriptional mechanisms. Through its catalytic activity to selectively process or degrade RNAs, the RNA exosome complex dictates the levels of RNAs comprising multiple RNA classes, thereby regulating chromatin structure, gene expression and differentiation. Although the RNA exosome would be expected to control diverse biological processes, studies to elucidate its biological functions and how it integrates into, or functions in parallel with, cell type-specific transcriptional mechanisms are in their infancy. Mechanistic analyses have demonstrated that the RNA exosome confers expression of a differentiation regulatory receptor tyrosine kinase, downregulates the telomerase RNA component TERC, confers genomic stability and promotes DNA repair, which have considerable physiological and pathological implications. In this review, we address how a broadly operational RNA regulatory complex interfaces with cell type-specific machinery to control cellular differentiation.

scholarly journals CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the β-globin locus

2012 ◽  
Vol 40 (16) ◽  
pp. 7718-7727 ◽  
Author(s):  
Ivan Junier ◽  
Ryan K. Dale ◽  
Chunhui Hou ◽  
François Képès ◽  
Ann Dean
Keyword(s):  
Transcriptional Regulation ◽  
Chromosome Organization ◽  
Cell Type ◽  
Specific Chromosome ◽  
Cell Type Specific

scholarly journals Cell-type specific regulation of thrombospondin-1 expression and its promoter activity by regulatory agents

2001 ◽  
Vol 33 (3) ◽  
pp. 117-123 ◽  
Author(s):  
Soo-A Kim ◽  
Jong-Hoon Kang ◽  
Inho Cho ◽  
Sung-Won Bae ◽  
Kyong-Ja Hong
Keyword(s):  
Promoter Activity ◽  
Cell Type ◽  
Thrombospondin 1 ◽  
Cell Type Specific ◽  
Specific Regulation

scholarly journals Cell type-specific transcriptional regulation of the human adenosine deaminase gene

1989 ◽  
Vol 17 (3) ◽  
pp. 1061-1076 ◽  
Author(s):  
David L. Lattier ◽  
J.Christopher States ◽  
John J. Hutton ◽  
Dan A. Wiginton
Keyword(s):  
Transcriptional Regulation ◽  
Adenosine Deaminase ◽  
Cell Type ◽  
Cell Type Specific

scholarly journals Nr2e3-directed transcriptional regulation of genes involved in photoreceptor development and cell-type specific phototransduction

2009 ◽  
Vol 89 (3) ◽  
pp. 365-372 ◽  
Author(s):  
Neena B. Haider ◽  
Nissa Mollema ◽  
Meghan Gaule ◽  
Yang Yuan ◽  
Andrew J. Sachs ◽  
...  
Keyword(s):  
Transcriptional Regulation ◽  
Cell Type ◽  
Cell Type Specific ◽  
Photoreceptor Development
Sign in / Sign up

Export Citation Format

Share Document