scholarly journals Intracellular Positioning of Isoforms Explains an Unusually Large Adenylate Kinase Gene Family in the Parasite Trypanosoma brucei

2005 ◽  
Vol 280 (12) ◽  
pp. 11781-11789 ◽  
Author(s):  
Michael L. Ginger ◽  
E. Solange Ngazoa ◽  
Claudio A. Pereira ◽  
Timothy J. Pullen ◽  
Mostafa Kabiri ◽  
...  
Keyword(s):  
Gene Family ◽  
Trypanosoma Brucei ◽  
Adenylate Kinase ◽  
Kinase Gene

An expanded adenylate kinase gene family in the protozoan parasite Trypanosoma cruzi

2006 ◽  
Vol 1760 (6) ◽  
pp. 913-921 ◽  
Author(s):  
Leon A. Bouvier ◽  
Mariana R. Miranda ◽  
Gaspar E. Canepa ◽  
Maria Júlia M. Alves ◽  
Claudio A. Pereira
Keyword(s):  
Trypanosoma Cruzi ◽  
Gene Family ◽  
Adenylate Kinase ◽  
Protozoan Parasite ◽  
Kinase Gene

scholarly journals The Evolutionary History and Diverse Physiological Roles of the Grapevine Calcium-Dependent Protein Kinase Gene Family

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e80818 ◽  
Author(s):  
Fei Chen ◽  
Marianna Fasoli ◽  
Giovanni Battista Tornielli ◽  
Silvia Dal Santo ◽  
Mario Pezzotti ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Gene Family ◽  
Evolutionary History ◽  
Dependent Protein Kinase ◽  
Kinase Gene ◽  
Calcium Dependent ◽  
Dependent Protein ◽  
Protein Kinase Gene ◽  
Calcium Dependent Protein Kinase

Mapping of tyrosine kinase gene family members in aXiphophorus melanoma model

1998 ◽  
Vol 22 (3) ◽  
pp. 150-157 ◽  
Author(s):  
Donald C. Morizot ◽  
Brenda B. McEntire ◽  
Luis Della Coletta ◽  
Steven Kazianis ◽  
Manfred Schartl ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Gene Family ◽  
Family Members ◽  
Kinase Gene ◽  
Melanoma Model ◽  
Tyrosine Kinase Gene

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

1993 ◽  
Vol 13 (4) ◽  
pp. 2031-2040 ◽  
Author(s):  
M K Webster ◽  
L Goya ◽  
Y Ge ◽  
A C Maiyar ◽  
G L Firestone
Keyword(s):  
Protein Kinase ◽  
Gene Family ◽  
Consensus Sequence ◽  
Transcriptional Level ◽  
Rat Tissues ◽  
Dependent Manner ◽  
Kinase Gene ◽  
Mammary Tumor Cell ◽  
Mammary Tumor Cell Line ◽  
Protein Kinase Gene

A novel member of the serine/threonine protein kinase gene family, designated sgk, for serum and glucocorticoid-regulated kinase, was identified in a differential screen for glucocorticoid-inducible transcripts expressed in the Con8.hd6 rat mammary tumor cell line. sgk encodes a protein of 49 kDa which has significant sequence homology (45 to 55% identity) throughout its catalytic domain with rac protein kinase, the protein kinase C family, ribosomal protein S6 kinase, and cyclic AMP-dependent protein kinase. sgk mRNA is expressed in most adult rat tissues, with the highest levels in the thymus, ovary, and lung, as well as in several rodent and human cell lines. sgk mRNA was stimulated by glucocorticoids and by serum within 30 min, and both inductions were independent of de novo protein synthesis. The transcriptional regulation by glucocorticoids is a primary response, since the promoter of sgk contains a glucocorticoid response element consensus sequence 1.0 kb upstream of the start of transcription which is able to stimulate chloramphenicol acetyltransferase reporter gene activity in a dexamethasone-dependent manner. Antibodies that specifically recognize sgk-encoded protein on an immunoblot were generated. This protein was shown to increase in abundance with glucocorticoid treatment in a manner which paralleled the mRNA accumulation. This is the first report of a presumed serine/threonine protein kinase that is highly regulated at the transcriptional level by glucocorticoid hormones and suggests a novel interplay between glucocorticoid receptor signalling and a protein kinase of the second messenger family.

scholarly journals Genome-Wide Mining and Identification of Protein Kinase Gene Family Impacts Salinity Stress Tolerance in Highly Dense Genetic Map Developed from Interspecific Cross between G. hirsutum L. and G. darwinii G. Watt

Agronomy ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 560 ◽  
Author(s):  
Muhammad Shehzad ◽  
Zhongli Zhou ◽  
Allah Ditta ◽  
Xiaoyan Cai ◽  
Majid Khan ◽  
...  
Keyword(s):  
Salt Stress ◽  
Gene Family ◽  
Stress Tolerance ◽  
Genetic Map ◽  
Interspecific Cross ◽  
Genetic Erosion ◽  
Growth And Yield ◽  
Limiting Factor ◽  
Kinase Gene ◽  
Cotton Species

Abiotic stress is an important limiting factor in crop growth and yield around the world. Owing to the continued genetic erosion of the upland cotton germplasm due to intense selection and inbreeding, attention has shifted towards wild cotton progenitors which offer unique traits that can be introgressed into the cultivated cotton to improve their genetic performance. The purpose of this study was to characterize the Pkinase gene family in a previously developed genetic map of the F2 population derived from a cross between two cotton species: Gossypium hirsutum (CCRI 12-4) and Gossypium darwinii (5-7). Based on phylogenetic analysis, Pkinase (PF00069) was found to be the dominant domain with 151 genes in three cotton species, categorized into 13 subfamilies. Structure analysis of G. hirsutum genes showed that a greater percentage of genes and their exons were highly conserved within the group. Syntenic analysis of gene blocks revealed 99 duplicated genes among G. hirsutum, Gossypium arboreum and Gossypium raimondii. Most of the genes were duplicated in segmental pattern. Expression pattern analysis showed that the Pkinase gene family possessed species-level variation in induction to salinity and G. darwinii had higher expression levels as compared to G. hirsutum. Based on RNA sequence analysis and preliminary RT-qPCR verification, we hypothesized that the Pkinase gene family, regulated by transcription factors (TFs) and miRNAs, might play key roles in salt stress tolerance. These findings inferred comprehensive information on possible structure and function of Pkinase gene family in cotton under salt stress.

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