scholarly journals Repression of the Human Sex Hormone-binding Globulin Gene in Sertoli Cells by Upstream Stimulatory Transcription Factors

2004 ◽  
Vol 280 (6) ◽  
pp. 4462-4468 ◽  
Author(s):  
David M. Selva ◽  
Kevin N. Hogeveen ◽  
Geoffrey L. Hammond
Keyword(s):  
Transcription Factors ◽  
Sertoli Cells ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Globulin Gene

SEX HORMONE BINDING GLOBULIN GENE POLYMORPHISM AND RISK OF TYPE2 DIABETES MELLITUS IN EGYPTIAN MEN

2014 ◽  
Vol 20 (2) ◽  
pp. 1-7
Author(s):  
Shereen El Tarhouny ◽  
Soha Zakaria ◽  
Khaled d Hadhoud ◽  
Manal Hanafi ◽  
Azza Kamel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Type2 Diabetes ◽  
Type2 Diabetes Mellitus ◽  
Globulin Gene

Sex hormone binding globulin in arterial, and in peripheral, hepatic, renal and spermatic venous blood of children and adults

1983 ◽  
Vol 103 (3) ◽  
pp. 428-432 ◽  
Author(s):  
A. Belgorosky ◽  
C. Scorticati ◽  
M. A. Rivarola
Keyword(s):  
Sertoli Cells ◽  
Venous Blood ◽  
Hepatic Clearance ◽  
Sex Hormone ◽  
Splanchnic Circulation ◽  
Sex Hormone Binding Globulin ◽  
Seminiferous Tubules ◽  
Hormone Binding ◽  
Peripheral Tissues ◽  
Arterial Blood

Abstract. Human sex hormone binding globulin (SHBG) was measured in arterial serum and in serum obtained from different venous territories. In 6 children, SHBG ranged from 44.4 ± 4.8 (mean ± sd) in arterial blood to 55.3 ± 5.3 in the hepatic vein (P < 0.01), while it did not change significantly in renal or peripheral tissue venous blood. In 6 male adults, no significant arteriovenous differences were found either in the peripheral tissues or in the splanchnic circulation. In the spermatic vein of 8 subjects, SHGB was significantly lower (17.1 ± 5.7) than in the arterial blood (22.8 ± 7.5), P < 0.025. The arterio-venous difference found in the splanchnic circulation of children supports the hepatic origin of SHBG, and also suggests extra-hepatic clearance of the binding globulin. Testicular uptake of SHBG might be necessary to regulate delivery of androgens to Sertoli cells in the seminiferous tubules.

The (TAAAA)npolymorphism of sex hormone-binding globulin gene is not associated with testicular maldescent

Andrologia ◽  
2012 ◽  
Vol 45 (1) ◽  
pp. 40-45 ◽  
Author(s):  
C. Mamoulakis ◽  
N. Sofikitis ◽  
P. Tsounapi ◽  
E. Vlachopoulou ◽  
A. Chatzikyriakidou ◽  
...  
Keyword(s):  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Globulin Gene

Evidence that human placenta is a site of sex hormone-binding globulin gene expression

1993 ◽  
Vol 46 (4) ◽  
pp. 497-505 ◽  
Author(s):  
Fernando Larrea ◽  
Lorenza Díaz ◽  
Cecilia Cariño ◽  
Jorge Larriva-Sahdd ◽  
Laura Carrillo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Human Placenta ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
A Site ◽  
Globulin Gene
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