scholarly journals Essential Role of GATA3 for the Maintenance of Type 2 Helper T (Th2) Cytokine Production and Chromatin Remodeling at the Th2 Cytokine Gene Loci

2004 ◽  
Vol 279 (26) ◽  
pp. 26983-26990 ◽  
Author(s):  
Masakatsu Yamashita ◽  
Maki Ukai-Tadenuma ◽  
Takeshi Miyamoto ◽  
Kaoru Sugaya ◽  
Hiroyuki Hosokawa ◽  
...  
Keyword(s):  
Chromatin Remodeling ◽  
Essential Role ◽  
Cytokine Production ◽  
Cytokine Gene ◽  
Th2 Cytokine

Chromatin remodeling at the Th2 cytokine gene loci in human type 2 helper T cells

2007 ◽  
Vol 44 (9) ◽  
pp. 2249-2256 ◽  
Author(s):  
Takaaki Kaneko ◽  
Hiroyuki Hosokawa ◽  
Masakatsu Yamashita ◽  
Chrong-Reen Wang ◽  
Akihiro Hasegawa ◽  
...  
Keyword(s):  
T Cells ◽  
Chromatin Remodeling ◽  
Helper T Cells ◽  
Cytokine Gene ◽  
Human Type ◽  
Th2 Cytokine

scholarly journals The essential role of exercise in the management of type 2 diabetes

2017 ◽  
Vol 84 (7 suppl 1) ◽  
pp. S15-S21 ◽  
Author(s):  
John P. Kirwan ◽  
Jessica Sacks ◽  
Stephan Nieuwoudt
Keyword(s):  
Type 2 Diabetes ◽  
Essential Role

Chromatin remodeling of the Th2 cytokine gene loci

2005 ◽  
Vol 1285 ◽  
pp. 137-144
Author(s):  
T. Nakayama ◽  
M. Yamashita ◽  
M. Kimura ◽  
A. Hasegawa ◽  
M. Omori ◽  
...  
Keyword(s):  
Chromatin Remodeling ◽  
Cytokine Gene ◽  
Th2 Cytokine

scholarly journals Essential Role of p400/mDomino Chromatin-remodeling ATPase in Bone Marrow Hematopoiesis and Cell-cycle Progression

2010 ◽  
Vol 285 (39) ◽  
pp. 30214-30223 ◽  
Author(s):  
Toshihiro Fujii ◽  
Takeshi Ueda ◽  
Shigekazu Nagata ◽  
Rikiro Fukunaga
Keyword(s):  
Cell Cycle ◽  
Bone Marrow ◽  
Chromatin Remodeling ◽  
Cell Cycle Progression ◽  
Essential Role ◽  
Cycle Progression

scholarly journals Role of the Mac-1 and VLA-4 integrins, and concomitant Th2-cytokine production, in nitric oxide modulated eosinophil migration from bone marrow to lungs in allergic mice

2011 ◽  
Vol 11 (2) ◽  
pp. 204-211 ◽  
Author(s):  
Edmar Henrique Pelaquini ◽  
Lucila de Assis Figueiredo Guimarães ◽  
Letícia Regina Benetti ◽  
Luiz Gustavo Romani Fernandes ◽  
Wirla Maria da Silva Cunha Tamashiro ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bone Marrow ◽  
Cytokine Production ◽  
Eosinophil Migration ◽  
Th2 Cytokine

Effect of prolonged exercise and carbohydrate ingestion on type 1 and type 2 T lymphocyte distribution and intracellular cytokine production in humans

2005 ◽  
Vol 98 (2) ◽  
pp. 565-571 ◽  
Author(s):  
G. I. Lancaster ◽  
Q. Khan ◽  
P. T. Drysdale ◽  
F. Wallace ◽  
A. E. Jeukendrup ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
T Lymphocyte ◽  
Cytokine Production ◽  
Stress Hormone ◽  
Induced Stress ◽  
Ifn Γ ◽  
Exercise Induced

The present study was undertaken to examine the role of the exercise-induced stress hormone response on the regulation of type 1 and type 2 T lymphocyte intracellular cytokine production. Subjects performed 2.5 h of cycling exercise at 65% maximal O2 uptake while ingesting a 6.4% carbohydrate (CHO) solution, 12.8% CHO solution, or a placebo. Peripheral whole blood samples were stimulated and stained for T lymphocyte surface antigens (CD4 and CD8). Cells were then permeabilized, stained for intracellular cytokines, and analyzed using flow cytometry. Exercise resulted in a decrease ( P < 0.05) in the number and percentage of IFN-γ positive CD4+ and CD8+ T lymphocytes. These stimulated cells produced less IFN-γ immediately postexercise ( P < 0.05) and 2-h postexercise ( P < 0.05) compared with preexercise. However, CHO ingestion, which attenuated the exercise-induced stress hormone response compared with placebo ( P < 0.05), prevented both the decrease in the number and percentage of IFN-γ-positive CD4+ and CD8+ T lymphocytes and the suppression of IFN-γ production from stimulated CD4+ and CD8+ T lymphocytes. There was no effect of exercise on the number of, or cytokine production from, IL-4-positive CD4+ or CD8+ T lymphocytes. These data provide support for the role of exercise-induced elevations in stress hormones in the regulation of type 1 T lymphocyte cytokine production and distribution.

scholarly journals Essential Role of IL-12 in Angiogenesis in Type 2 Diabetes

2017 ◽  
Vol 187 (11) ◽  
pp. 2590-2601 ◽  
Author(s):  
Maha Ali ◽  
Vishal Mali ◽  
Samuel Haddox ◽  
Soad M. AbdelGhany ◽  
Sahar E.M. El-deek ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Essential Role
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